HistorySummary
Our research focus is cell kinetics of mRNA, DNA, protein and transcriptional factors, at the cellular and tissue levels by using molecular histochemical and molecular biological methods.
Research projects
- Advances in in situ hybridization techniques
- Estrogen regulation on mitochondrial dynamics
- Estrogen effect in cellular kinetics during the liver regeneration
- Epigenetic regulation in of inflammatory bowel disease
Laboratory Techniques
- Molecular histochemical methods (In situ hybridization, Immunohistochemistry, Southwestern histochemistry)
- Gene transfection by electroporation method (in vivo & in vitro)
International Collaboration
- Department of Medical Research, Lower and Upper Myanmar, Myanmar
- Mongolian National University of Medical Sciences, Mongolia
- National Cheng Kun University (Taiwan)
- Nong Lam University of Ho Chi Minh City, Vietnam
Publications
- Takagi H, Arimura K, Uto T, Fukaya T, Nakamura T, Choijookhuu N, Hishikawa Y, Sato K.: Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation. Sci Rep. 2016 Apr. doi: 10.1038/srep24477 (In Press)
- Yamaguchi Y, Madhyastha H, Madhyastha R, Choijookhuu N, Hishikawa Y, Pengjam Y, Nakajima Y, Maruyama M.: Arsenic acid inhibits proliferation of skin fibroblasts, and increases cellular senescence through ROS mediated MST1-FOXO signaling pathway. J Toxicol Sci. 41:105-113, 2016
- Choijookhuu N, Hino SI, Oo PS, Batmunkh B, Hishikawa Y.: The role of estrogen receptors in intestinal homeostasis and disease. Receptors Clin Investig. 2016 Vol 3, No 1; doi: 10.14800/rci.1109
- Muraoka I, Takatsuki M, Sakai Y, Tomonaga T, Soyama A, Hidaka M, Koji T, Utoh R, Ohashi K, Okano T, Kanematsu T, Eguchi S.: Transplanted fibroblast cell sheets promote migration of hepatic progenitor cells in the incised host liver in allogenic rat model. J Tissue Eng Regen Med. 11:E108-115, 2015.
- Choijookhuu N, Hino SI, Oo PS, Batmunkh B, Ali MN, Kyaw MTH, Hishikawa Y.: Ontogenetic changes in the expression of estrogen receptor β in mouse duodenal epithelium. Clin Res Hepatol Gastroenterol. 39, 499-507, 2015
(For more information: http://www.med.miyazaki-u.ac.jp/home/anatomy1eng)