宮崎大学医学部附属病院 検査部

ISO15189認定施設
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検査部案内

原著英文（1976～2005年）

  1. Hamaguchi Y, Yoshitake S, Ishikawa E, Endo Y, Ohtaki S : Improved procedure for the conjugation of rabbit IgG and Fab’ antibodies with -D-galactosidase from Escherichia coli using N,N’-o-phenylenedimaleimide. J Biochem 85 : 1289-1300 , 1979
  2. Endo Y, Nakano J, Ohtaki S, Izumi M, Hamaguchi Y, Yoshitake S, Ishikawa E : An enzyme immunoassay for the measurement of thyroglobulin in human serum. Clin Chim Acta 95 : 325-336 , 1979
  3. Ohtaki S, Nakagawa H, Yamazaki I : Reaction of detergentsolubilized thyroid peroxidase with hydrogen peroxide. FEBS Lett 109 : 71-74 , 1980
  4. Endo Y, Nakano J, Horiuchi K, Ohtaki S, Izumi M, Ishikawa E : An enzyme immunoassay for the measurement of anti-thyroglobulin autoantibody in human serum. Clin Chim Acta 103 : 67-77 , 1980
  5. Ishikawa E, Yoshitake S, Endo Y, Ohtaki S : Highly sensitive enzyme immunoassay of rabbit (anti-human IgG) IgG using human IgG- -galactosidase conjugate. FEBS Lett 111 : 353-355 , 1980
  6. Ohtaki S, Nakagawa H, Kimura S, Yamazaki I : Analyses of catalytic intermediates of hog thyroid peroxidase during its iodinating reaction. J Biol Chem 256 :805-810 , 1981
  7. Ohtaki S, Endo Y, Horinouchi K, Yoshitake S, Ishikawa E : Circulating thyroglobulin antithyroglobulin immune complex in thyroid disease using enzyme linked immunoassays. J Clin Endcrinol Metabol 52 : 239-246 , 1981
  8. Nakagawa H, Endo Y, Ohtaki S : Stimulation of protein-bound iodine formation by lipid extracts from hog thyroid microsomes. Endocrinol Japon 28 : 409-417 , 1981
  9. Endo Y, Nakagawa H, Aikawa E, Ohtaki S : Iodide transport of thyroid plasma membranes. Acta Endocrinol 98 : 227-233 , 1981
  10. Nakagawa H, Endo Y, Ohtaki S : A new protease in hog thyroid lysosomes. I. The presence of a leupeptin sensitive protease in the soluble fraction of thyroid lysosomes. Acta Endocrinol 98 : 383-389 , 1981
  11. Nakagawa H, Endo Y, Ohtaki S : A new protease in hog thyroid lysosomes.II.A partial purification and characterization of a leupeptin sensitive protease. Acta Endcrinol 98 : 390-395 , 1981
  12. Imagawa M, Yoshitake S, Ishikawa E, Endo Y, Ohtaki S, Kano E, Tsunetoshi Y : Highly sensitive sandwich enzyme immunoassay of human IgE with -galactosidase from Escherichia coli. Clin Chim Acta 117 : 119-207 , 1981
  13. Tawara S, Araki S, Toshimori K, Nakagawa H, Ohtaki S : Amyloid fibril protein in type I familial amyloidotic polyneuropathy in Japanese. J Lab Clin Med 98 : 811-822 , 1981
  14. Hamada K, Tanaka T, Yoshii O, Saito S, Hayakawa K, Kida N, Ohtaki S : Serum lipid and lipoprotein levels in school age population of a middle-class urban town in Japan. Acta Paediat Japan 23 : 368-376 , 1981
  15. Ohtaki S, Nakagawa H, Nakamura M, Yamazaki I : Reactions of purified hog thyroid peroxidase with H2O2, tyrosine, and methylmercaptoimidazole (goitrogen) in comparison with bovine lactoperoxidase. J Biol Chem 257 : 761-766 , 1982
  16. Yoshitake S, Endo Y, Nakagawa K, Imagawa M, Ohtaki S, Ishikawa E : A sandwich enzyme immunoassay of human growth hormone in serum using anti-human growth hormone IgG- -D-galactosidase conjugate. Clin Chim Acta 125 : 1-7 , 1982
  17. Ohtaki S, Nakagawa H, Nakamura M, Yamazaki I : One -and two- electron oxidations of tyrosine, monoiodotyrosine, and diiodotyrosine catalyzed by hog thyroid peroxidase. J Biol Chem 257 : 13398-13403 , 1982
  18. Endo Y, Ohtaki S, Kan H, Yoshitake S, Ishikawa E : A simultaneous enzyme-linked immunoassay for human thyroglobulin. Anal Lett 15 : 1301-1315 , 1982
  19. Nakagawa H, Kida N, Maeda M, Wakuta Y, Ohtaki S : An abnormal Isoenzyme of creatine kinase in the serum of a patient with metastatic carcinoma : Identity with mitochondrial creatine kinase. Clin Chem 28 : 723-725 , 1982
  20. Hamada K, Tanaka T, Yoshida O, Saito S, Hayakawa K, Kida N, Ohtaki S, Sakai Y, Mabuchi H : Pseudohomozygous type II hyperlipoproteinemia. Jap J Human Genet 27 : 259-264 , 1982
  21. Hashida S, Nakagawa K, Yoshitake S, Imagawa M, Ishikawa E, Endo Y, Ohtaki S, Ichioka Y, Nakajima K : A highly sensitive sandwich enzyme immunoassay of human growth hormone in serum using affinity-purified anti-human growth hormone Fab’-horseradish peroxidase conjugate. Anal Lett 16 : 31-44 , 1983
  22. Endo Y, Aratake Y, Yamamoto I, Nakagawa H, Kuribayashi T, Ohtaki S : Peripheral K cells in Graves’ disease and Hashimoto’s thyroiditis in relation to circulating immune complexes. Clin Endocrinol 18 : 187-194 , 1983
  23. Nakamura M, Yamazaki I, Nakagawa H, Ohtaki S : Steady state kinetics and regulation of thyroid peroxidase-catalyzed iodination. J Biol Chem 258 : 3837-3842 , 1983
  24. Nakamura M, Yamazaki I, Nakagawa H, Ohtaki S : Steady state kinetics and regulation of thyroid peroxidase-catalyzed iodination. J Biol Chem 258 : 3837-3842 , 1983
  25. Kosugi T, Takagi I, Kinjo K, Aratake Y, Ohtaki S, Mihara H : The detection of fibrinogen (or FgDP)-protamine sulphate complex in vitro and in the circulating blood. Intern J Tissue Reactions 5 : 47-54 , 1983
  26. Nakagawa H, Ohtaki S : Orientation of thyroid peroxidase in hog thyroid microsomes. J Biochem 94 : 155-162 , 1983
  27. Endo Y, Matsunaga S, Ohtaki S, Ishikawa E : A simultaneous enzyme-linked immunoassay for anti-thyroglobulin autoantibody in human serum. Anal Lett 16 : 1303-1319 , 1983
  28. Nakagawa H, Umeki K, Yamanaka K, Kida N, Ohtaki S : Macromolecular alkaline phosphatase and an immunoglobulin G that inhibited alkaline phosphatase in a patient’s serum. Clin Chem 29 : 375-378 , 1983
  29. Hashida S, Nakagawa K, Imagawa M, Inoue S, Yoshitake S, Ishikawa E, Endo Y, Ohtaki S, Ichioka Y, Nakajima K : Use of inorganic salts to minimize serum interference in sandwich enzyme immunoassay for human growth hormone using Fab’-horseradish peroxidase conjugate. Clin Chim Acta 135 : 263-273 , 1983
  30. Ohtaki S, Nakagawa H, Kida N, Nakamura H, Tsuda K, Yokoyama S, Yamamura T, Tajima S, Yamamoto A : A Japanese family with high density lipoprotein deficiency. Atheroslerosis 49 : 79-88 , 1983
  31. Nakamura M, Yamazaki I, Nakagawa H, Ohtaki S, Ui N : Iodination and oxidation of thyroglobulin catalyzed by thyroid peroxidase. J Biol Chem 259 : 359-364 , 1984
  32. Tamura K, Aratake Y, Endo Y, Ohtaki S : Clinical significance of autorosette-forming cells in T-cell lymphoma. Leukemia Res 8 : 275-283 , 1984
  33. Nakagawa H, Ohtaki S : Simultaneous purification and characterization of two thiol proteases from hog thyroid lysosomes. Endocrinology 115 : 33-40 , 1984
  34. Endo Y, Aratake Y, Kotani T, Kuribayashi T, Tamura K, Ohtaki S : Increase in autorosette-forming lymphocytes in thyroid diseases. Endocrinol Japon 31 : 627-634 , 1984
  35. Ohtaki S, Nakagawa H, Nakamura S, Nakamura M, Yamazaki I : Characterization of hog thyroid peroxidase. J Biol Chem 260 : 441-448 1985
  36. Kotani T, Maeda M, Ohtaki S, Kobayashi S, Okuyama H : Analyses of the specificity of mouse monoclonal antibodies to syngeneic and allogeneic thyroglobulins. Clin Immunol Immunopathol 34 : 147-157 , 1985
  37. Kotani T, Maeda M, Umeki K, Ohtaki S : Epitopic difference among rat thyroglobulins. Immunol Lett 9 : 167-172 , 1985
  38. Nakagawa H, Kotani T, Ohtaki S, Nakamura M, Yamazaki I : Purification of thyroid peroxidase by monoclonal antibody-assisted immunoaffinity chromatography. Biochem Biophys Res Commun 127 : 8-14 , 1985
  39. Nakagawa H, Ohtaki S : Thyroxine (T4) release from thyroglobulin and its T4-containing peptide by thyroid thiol protease. Endocrinology 116 : 1433-1439 , 1985
  40. Nakagawa H, Kotani T, Ohtaki S, Kawano J, Aikawa E, Imagawa M, Hashida S, Ishikawa E : Characterization of a monoclonal antibody to hog thyroid peroxidase and its use for immunohistochemical localization of the peroxidase in the thyroid gland. J Biochem 97 : 1709-1718 1985
  41. Tamura K, Aratake Y, Kotani T, Seita M, Ohtaki S : Identification of complex phenotype (OKT4+ / OKT8+) on adult type T-cell leukemia cells by sequential application of indirect rosette assay with Protein A-coated ox red blood cells and immunoperoxidase technic. Am J Clin Pathol 84 : 44-48 , 1985
  42. Nakamura M, Yamazaki I, Ohtaki S : Detection of a catalytic intermediate of peroxidase in hog thyroid microsomes. Biochem Biophys Res Commun 131 : 681-686 , 1985
  43. Hashida S, Nakagawa K, Ishikawa E, Ohtaki S : Basal level of human growth hormone (hGH) in normal serum. Clin Chim Acta 151 : 185-186 , 1985
  44. Hashida S, Ishikawa E, Nakagawa K, Ohtaki S, Ichioka T, Nakajima K : Demonstration of human growth hormone in normal urine by a highly specific and sensitive sandwich enzyme immunoassay. Anal Lett 18 : 1623-1634 , 1985
  45. Nakamura M, Yamazaki I, Kotani T, Ohtaki S : Thyroid peroxidase selects the mechanism of either 1- or 2 -electron oxidation of phenols, depending on their substituents. J Biol Chem 260 : 13546-13552 , 1985
  46. Tamura K, Unoki T, Sagawa K, Aratake Y, Kitamura T, Tachibana N, Ohtaki S, Yamaguchi K, Seita M : Clinical features of OKT4+/OKT8+ adult T-cell leukemia. Leukemia Res 9 : 1353-1359 , 1985
  47. Tamura K, Nagamine N, Araki Y, Seita M, Okayama A, Kawano K, Tachibana N, Tsud K, Kuroki Y, Narita H, Inoue S, Suzumiya J, Sumiyoshi A, Aratake Y, Ohtaki S, Torigoe J, Kawachi J : Clinical analysis of 33 patients with adult T-cell leukemia (ATL)-diagnostic criteria and significance of high- and low-risk ATL. Intern J Cancer 37 : 335-341 , 1986
  48. Tanaka T, Kotani T, Ohtaki S, Nagai K, Tsuruta K, Mori N : Labile oligomeric structure of human placental 15-hydroxyprostaglandin dehydrogenase. Biochem Biophys Res Commun 135 : 1058-1063 , 1986
  49. Shigenaga H, Yoshii O, Togoe T, Hayakawa K, Hamada K, Kida K, Ohtaki S : Serum lipid and lipoproteins concentrations in obese children as atherogenic risk factors. Acta Paediatr Jpn 28 : 38-45 , 1986
  50. Kotani T, Umeki K, Matsunaga S, Kato E, Ohtaki S : Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting. J Clin Endocrinol Metabol 62 : 928-933 , 1986
  51. Hashida S, Ishikawa E, Nakagawa K, Ohtaki S, Shigenaga H, Hayakawa K, Mohri Z, Murakami Y, Ichioka T, Nakajima K :Level of human growth hormone (hGH) in urine determined by a highly specific and sensitive sandwich enzyme immunoassay. Anal Lett 19 : 625-638 , 1986
  52. Kotani T, Kato E, Hirai K, Kuma K, Ohtaki S : Immunoglobulin G subclasses of anti-thyroid peroxidase autoantibodies in human autoimmune thyroid diseases. Endocrinol Japon 33 : 505-510 , 1986
  53. Ohtaki S, Kotani T, Nakamura Y : Characterization of human thyroid peroxidase purified by monoclonal antibody-assisted chromatography. J Clin Endocrinol Metabol 63 : 570-576 , 1986
  54. Hashida S, Ishikawa E, Tanaka K, Shimizu N, Nakagawa K, Ohtaki S : Serum concentration of human growth hormone (hGH) after administration of the somatostatin analogue SMS 201-995 in normal subjects. Clin Chim Acta 159 : 93-95 , 1986
  55. Kotani T, Umeki K, Ohtaki S : A murine monoclonal antibody derived from the immunization of human thyroglobulin reacts equally mith L-thyroxine and reverse triiodo-L-thyronine and has unique idiotype. Endocrinol Japan 33 : 629-636 , 1986
  56. Nakamura M, Yamazaki I, Ohtaki S, Nakamura S : Characterization of one- and two-electron oxidations of glutathione coupled with lactoperoxidase and thyroid peroxidase reactions. J Biol Chem 261 : 13923-13927 , 1986
  57. Nakamura Y, Miyamoto T, Koono M, Ohtaki S : Active calcium transport by orcine thyroid microsomes. Endocrinology 119 : 2058-2065 , 1986
  58. Shimada M, Kotani T, Ohtaki S, Tateno S, Tanigawa H, Katsuki T : Primary perianal actinomycosis over a thirty year period. Jap J Surgery 16 : 302-304 , 1986
  59. Kotani T, Ohtaki S : Characterization of thyroid follicular cell apical plasma membrane peroxidase using monoclonal antibody. Endocrinol Japon 34 : 407-413 , 1987
  60. Kotani T, Aratake Y, Ishiguro R, Yamamoto I, Uemura Y, Tamura K, Ohtaki S : Influence of physical exercise on large granular lymphocytes, Leu-7 bearing mononuclear cells and natural killer activity in peripheral blood-NK cell and NK-activity after physical exercise. Acta Hematol Japon 50 : 1210-1216 , 1987
  61. Nakamura Y, Ohtaki S : Calcium release from porcine thyroid microsomes by phosphatidylinositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate. Endocrinology 120 : 2302-2307 , 1987
  62. Kimura S, Kotani T, McBride OW, Umeki K, Hirai K, Nakayama T, Ohtaki S : Human thyroid peroxidase: Complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs. Proc Natl Acad Sci USA 84 : 5555-5559 , 1987
  63. Nakamura Y, Ogihara S, Ohtaki S : Activation by ATP of calcium-dependent NADPH-oxidase generating hydrogen peroxide in thyroid plasma membranes. J Biochem 102 : 1121-1132 , 1987
  64. Tamura K, Makino S, Araki Y, Seita M, Aratake Y, Ohtaki S, Sagawa K, Miwa M : A case of CD4+/CD8- adult T-cell leukemia with good response to Interferon-beta terminating as a CD4+/CD8+ adult T-cell lymphoma. Leukemia Res 11: 665-668 , 1987
  65. Aratake Y, Tamura K, Kotani T, Ohtaki S : Application of the avidin-biotin complex method for the light microscopic analysis of lymphocyte subsets with monoclonal antibodies on air-dried smears. Acta Cytol 32 : 117-122 , 1988
  66. Kondo Y, Inoue K, Kotani T, Ohtaki S : Immunoelectron microscopy of the hormonogenic sites of thyroglobulin molecule. Mol Cellul Endocrinol 57 : 261-267 , 1988
  67. Nakamura Y, Ohtaki S, Yamazaki I : Molecular mechanism of iodide transport by thyroid plasmalemmal vesicles: cooperative sodium activation and asymmetrical affinities for the ions on the outside and inside of the vesicles. J Biochem 104 : 544-549 , 1988
  68. Kotani T, Ohtaki S : A circulating thyroid peroxidase-like substance in healthy human peripheral blood. Endocrinol Japon 35 : 849-855 , 1988
  69. Tamura K, Araki Y, Makino S, Kawachi J, Torigoe J, Suzumiya J, Aratake Y, Sumiyoshi Y, Ohtaki S, Seita M : Ph1+ malignant histiocytosis. Acta Haematol Japon 51 : 1063-1068 , 1988
  70. Kawano J, Kotani T, Umeki K, Oinuma T, Ohtaki S, Akikawa E : A monoclonal antibody to rat liver arylsulfatase C and its application in immunohistochemistry. J Histochem Cytochem 37 : 683-690 , 1989
  71. Nakamura Y, Ohtaki S, Makino R, Tanaka T, Ishimura Y : Superoxide anion is the initial product in the hydrogen peroxide formation catalyzed by NADPH oxidase in porcine thyroid plasma membrane. J Biol Chem 264 : 4759-4761 , 1989
  72. Kimura S, Hong YS, Kotani T, Ohtaki S, Kikkawa F : Structure of the human thyroid peroxidase gene : Comparison and relationship to the human myeloperoxidase gene. Biochemistry 28 : 4481-4489 , 1989
  73. Hashimoto S, Nakajima R, Yamazaki I, Kotani T, Ohtaki S, Kitagawa T : Resonance Raman characterization of hog thyroid peroxidase : An SERRS study. FEBS Lett 248 : 205-209 , 1989
  74. Kimura S, Kotani T, Ohtaki S, Aoyama Y : cDNA-directed expression of human thyroid peroxidase. FEBS Lett 250 : 377-380 , 1989
  75. Nakamura M, Yamazaki I, kotani T, Ohtaki S : Thyroglobulin-mediated one- and two-electron oxidations of GSH and ascorbate in thyroid peroxidase systems. J Biol Chem 264 : 12909-12913 , 1989
  76. Kawano J, Kotani T, Ohtaki S, Minamino N, Matsuo H, Oinuma T, Aikawa E : Characterization of rat and human steroid sulfatases. Biochim Biophys Acta 997 : 199-205 , 1989
  77. Hata J, Yamashita S, Yagihashi S, Kato H, Kabeno S, Hirai K, Kuma K, Kimura S, Umeki K, Kotani T, Ohtaki S : Stable high level expression of human thyroid peroxidase in cultured chinese hamster ovary cells. Biochem Biophys Res Commun 164 : 1268-1273 , 1989
  78. Araki Y, Makino S, Tamura K, Seita M, Aratake Y, Ohtaki S : Limited value of chemotherapy for peripheral T-cell lymphoma. J Kyushu Hematol Soc 36 : 111-121 , 1989
  79. Kotani T, Umeki K, Hirai K, Ohtaki S : Experirnental murine thyroiditis induced by porcine thyroid peroxidase and its transfer by the antigen-specific T cell line. Clin Exp Immunol 80 : 11-18 , 1990
  80. Nakamura Y, Kotani T, Ohtaki S : Transcellular iodide transport and iodination on the apical plasma membrane by monolayer thyroid cells cultured on collagen coated filters. J Endocrinol 126 : 275-281 , 1990
  81. Nakamura Y, Ohtaki S : Extracellular ATP-induced production of hydrogen peroxide in porcine thyroid cells. J Endocrinol 126 : 283-287 , 1990
  82. Nakamura Y, Yamazaki I, Ohtaki S : Iodothyronine-induced catalytic activity of thyroid peroxidase. J Biochem 108 : 804-810 , 1990
  83. Nakamura Y, Makino R, Tanaka T, Ishimura Y, Ohtaki S : Mechanism of H2O2 production in porcine thyroid cells : evidence for intermediary formation of superoxide anion by NADPH-dependent H2O2 generating machinery. Biochemistry 30 : 4880-4886 , 1991
  84. Kotani T, Aratake Y, Ogata Y, Umeki K, Araki Y, Hirai K, Kuma K, Ohtaki S : Expression of dipeptidyl aminopeptidase IV activity in thyroid carcinoma. Cancer Lett 57 : 203-208 , 1991
  85. Aratake Y, Kotani T, Tamura K, Araki Y, Kuribayashi T, Konoe K, Ohtaki S : Dipeptidyl aminopeptidase IV staining of cytological preparations to distinguish benign from malignant thyroid diseses. Amer J Clin Pathol 96 : 306-310 , 1991
  86. Kotani T, Kawano J, Suganuma T, Hirai K, Umeki K, Aratake Y, Konoe K, Ohtaki S : Immunohistochemical localization of dipeptidyl aminopeptidase IV in thyroid papillary carcinoma. Intern J Exp Pathol 73 : 215-222 , 1992
  87. Kotani T, Umeki K, Yagihashi S, Hirai K, Ohtaki S : Indentification of thyroiditogenic epitope on porcine thyroid peroxidase for C57BL/6 mice. J Immunol 148 : 2084-2089 , 1992
  88. Kotani T, Asada Y, Aratake Y, Umeki K, Yamamoto I, Tokudome R, Hirai K, Kuma K, Konoe K, Araki Y, Ohtaki S : Diagnostic usefulness of dipeptidyl aminopeptidase IV monoclonal antibody in paraffin-embedded thyroid follicular tumours. J Pathol 168 : 41-45 , 1992
  89. Kotani T, Umeki K, Yamamoto I, Takeuchi M, Takechi S, Nakayama T, Ohtaki S : Nucleotide sequence of the cDNA encoding mouse thyroid peroxidase. Gene 123 : 289-290 , 1993
  90. Nakamura M, Ohtaki S : Formation and reduction of ascorbate radicals by hog thyroid microsomes. Arch Biochem Biophys 305 : 84-90 , 1993
  91. Choi-Miura NH, Sakamoto T, Ohtaki S, Nakamura H, Ishizawa S, Takagi Y, Gomi K, Tomita M : Elevated complement activities of sera from patients with high density lipoprotein deficiency (Tangier disease): the presence of normal level of clusterin and the possible implication in the atherosclerosis. Clin Exp Immunol 93 : 242-247 , 1993
  92. Asada Y, Aratake Y, Kotani T, Marutsuka K, Araki Y, Ohtaki S, Sumiyoshi A : Expression of dipeptidyl aminopeptidase IV activity in human lung carcinoma. Histopathology 23 : 265-270 , 1993
  93. Sakata S, Matsuda M, Takuno H, Ogawa T, Matsui I, Sarui H, Maekawa H, Kotani T, Okuda K, Tarutani O, Miura K : Immune recognition of hormonogenic sites of human thyroglobulin: Studies of Graves’ sera and a murine monoclonal antibody with hormone antibody activity. Enodocrine J 40 : 393-398 , 1993
  94. Kotani T, Aratake Y, Kondo S, Tamura K, Ohtaki S : Expression of functional Fas antigen on adult T cell leukemia. Leuk Res 18 : 305-310 , 1994
  95. Mizukami Y, Nonomura A, Michigishi T, Noguchi M, Nakamura S, Arai Y, Kotani T, Ohtaki S, Matsukawa S : Immunohistochemical demonstration of thyroid peroxidase (TPO) in human thyroid tissues from various thyroid diseases. Anticancer Res 14 : 1329-1334 , 1994)
  96. Kondo S, Mishiro N, Umeki K, Kotani T, Setoguchi M, Shingu S, Ohtaki S : Human T-lymphotropic virus type I (HTLV-I) DNA in an HTLV-I-endemic area. Transfusion 34 : 449-450 , 1994
  97. Endo Y, Onogi S, Umeki K, Yamamoto I, Kotani T, Ohtaki S, Fujita T : Regional localization of the gene for thyroid peroxidase to human chromosome 2p25 and mouse chromosome 12BC. Genomics 25 : 760-761 , 1995
  98. Tomlinson S, Jansen AM, Koudinov A, Ghiso JA, Choi-Miura NH, Rifkin MR, Ohtaki S, Nussenzweig V : High-density-lipoprotein-independent killing of Trypanosoma brucei by human serum. Mol Biochem Parasitol 70 : 131-138 , 1995
  99. Kotani T, Aratake Y, Hirai K, Fukazawa Y, Sato H, Ohtaki S : Apoptosis in thyroid tissue from patients with Hashimoto’s thyroiditis. Autoimmunity 20 :231-236 , 1995
  100. Tanaka T, Umeki K, Yamamoto I, Sakamoto F, Noguchi S. and Ohtaki S. : CD26 (dipeptidyl peptidase IV/DPPIV) as a novel molecular marker for differentiated thyroid carcinoma. Intern J Cancer 64 : 326-331 , 1995
  101. Tanaka T, Umeki K, Yamamoto I, Kotani T, Sakamoto F, Noguchi S, Ohtaki S : c-Kit proto-oncogene is more likely to lose expression in differentiated thyroid carcinoma than three thyroid-specific genes: thyroid peroxidase, thyroglobulin, and thyroid stimulating hormone receptor. Endocrine J 42 : 723-728 , 1995
  102. Kondo S, Kotani T, Tsumori S, Nakahara S, Aratake Y, Kobayashi M, Takahashi M, Inoue S, Ohtaki S : Identification of biclonal (duplex) leukaemic cells expressing either CD4+/CD8- or CD4-/CD8+ from a patient with adult T-cell leukaemia/lymphoma. Brit J Haematol 89 : 669-671 , 1995
  103. Umeki K, Tanaka T, Yamamoto I, Aratake Y, Kotani T, Sakamoto F, Noguchi S, Ohtaki S : Differential expression of dipeptidyl peptidase IV (CD26) and thyroid peroxidase in neoplastic thyroid tissues. Endocrine J 43 : 53-60 , 1996
  104. Suzuki M, Uno H, Yamashita K, Toyama T, Kubuki Y, Maeda K, Matsuoka H, Ohtaki S, Tsubouchi H : Clinical significance of CD45RO expression on peripheral blood mononuclear cells in HTLV-I-infected individuals. Brit J Haematol 92 : 401-409 , 1996
  105. Kondo S, Kotani T, Tamura K, Aratake Y, Uno H, Tsubouchi H, Inoue S, Niho Y, Ohtaki S : Expression of CD26/dipeptidyl peptidase IV in adult T-cell leukemia/lymphoma (ATLL). Leuk Res 20 : 357-363 , 1996
  106. Tanaka T, Umeki K, Yamamoto I, Sugiyama S, Noguchi S, Ohtaki S : Immunohistochemical loss of thyroid peroxidase in papillary thyroid carcinoma : Strong suppression of peroxidase gene expression. J Pathol 179 : 89-94 , 1996
  107. Kotani T, Aratake Y, Hirai K, Hirai I, Ohtaki S : High expression of heat shock protein 60 in follicular cells of Hashimoto’s thyroiditis. Autoimmunity 25 : 1-8 , 1996
  108. Nomura H, Sawada Y, Fujinaga K, Ohtaki S : Cloning and characterization of rat p27Kip1, a cyclin-dependent kinase inhibitor. Gene 191 : 211-218 , 1997
  109. Sawada Y, Nomura H, Endo Y, Umeki K, Fujita T, Ohtaki S, Fujinaga K : Cloning and characterization of the rat p130, a member of the retinoblastoma gene family. Biochim Biophys Acta 1361 : 20-28 , 1997
  110. Tanaka T, Umesaki N, Mizuno K, Chang L, Miyama M, Ohtaki S, Ogita S : Enhancement of apoptotic susceptibility in human endometrial epithelial cell line HHUA by transforming growth factor- 1. Horm Metab Res 30 : 61-65 , 1998
  111. Nomura H , Sawada Y, Ohtaki S : Interaction of p27 with E1A and its effect on CDK kinase activity. Biochem Biophys Res Commun 248 : 228-234 , 1998
  112. Kotani T, Ogata Y, Yamamoto I, Aratake Y, Kawano J, Suganuma T, Ohtaki S : Characterization of gastric Na+/I- symporter of the rat. Clin Immunol Immunopathol 89 : 271- 278 , 1998
  113. Shimada M, Kotani T, Sameshima H , Nagamine Y, Kodama Y, Ikenoue T, Kenri T, Sakaki T, Ohtaki S : Two patients with premature labour associated with Mycoplasma hominis infection. J Med Microbiol 47 : 179-182 , 1998
  114. Matsuura E, Kang Y, Kitakawa H, Ogata A, Kotani T, Ohtaki S, Nishi S : Modulation of T cell function by alpha-fetoprotein (AFP) : an in vivo study on porcine thyroid peroxidase-induced experimental autoimmune thyroidtis in transgenic mice producing human alfa-fetoprotein. Tumor Biology 20 : 162-171, 1999
  115. Hirai K, Kotani T, Aratake Y, Ohtaki S, Kuma K : Dipeptidyl peptidase IV (DPP IV/CD26) staining predicts distant metastasis of ‘benign’ thyroid tumor. Pathology International 49 : 264-265, 1999
  116. Kotani T, Umeki K, Yamamoto I, Maesaka H, Tachibana K, Ohtaki S : A novel mutation in the human thyroid peroxidase gene resulting in a total iodide organification defect. J Endocrinol 160 : 267-273 , 1999
  117. Kuwabara M, Onitsuka T, Nakamura K, Shimada M, Ohtaki S, Mikami Y : Mediastinitis due to Gordona sputi after CABG. J Cardiovasc Surg 40 : 675-677 , 1999
  118. Sawada Y, Miura Y, Umeki K, Tamaoki T, Fujinaga K, Ohtaki S : Cloning and characterization of a novel RNA-binding protein SRL300 with RS domains. Biochim Biophys Acta 1492 : 191-195 , 2000
  119. Suehiro K, Mizuguchi J, Nishiyama K, Iwanaga S, Farrell DH, Ohtaki S : Fibrinogen binds to integrin 5 1 via the carboxyl-terminal RGD site of -chain. J Biochem 128 : 705-710 , 2000
  120. Kawano J, Kotani T, Ogata Y, Ohtaki S, Takecki S, Nakayama T, Sawaguchi A, Nagaike R, Oinuma T, Suganuma T : CALNUC (nucleobindin) is localized in the Golgi apparatus in insect cells. Eur J Cell Biol 79 : 208-217 , 2000
  121. Kotani T, Umeki K, Yamamoto I, Ohtaki S, Adachi M, Tachibana K : Iodide organification defects resulting from cosegregation of mutated and null thyroid peroxidase alleles. Mol Cell Endocrinol 182 : 61-68 , 2001
  122. Kawano J, Nakayama T, Takami Y, Kotani T, Sawaguchi A, Nagaike R, Oinuma T,Suganuma T : A monoclonal antibody against insect CALNUC recognizes the prooncoprotein EWS specifically in mammalian cells. Immunohistochemical and biochemical studies of the antigen in rat tissues. Histochem Cell Biol 115 : 421-428 , 2001
  123. Umeki K, Kotani T, Kawano J, Suganuma T, Yamamoto I, Aratake Y, Furujo M, Ichiba Y : Two novel missense mutations in the thyroid peroxidase gene, R665W and G771R, result in a localization defect and cause congenital hypothyroidism. Eur J Endocrinol 146 : 491-498 , 2002
  124. Kawano J, Nakayama T, Kotani T, Matsubayashi H, Ymamato M, Suganuma T : Identification and characterization of an insect homologue of the vertebrate Golgi apparatus protein 1 (MG-160/cysteine-rich fibroblast growth factor receptor/E-selectin ligand-1/latent transforming growth factor- complex protein-1) with a Golgi-specific monoclonal antibody. Histochem Cell Biol 117 : 381-389 , 2002
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掲載日：2012年10月30日