2020年
Bittel DC, Kibiryeva N, Kenmochi N, Patil P, Uechi T, Rongish B, Filla M, Marshall J, Artman M, Johnson R, O’BrienJr JE.
The role of alternative mRNA splicing in heart development.
In: Nakanishi T., Baldwin H., Fineman J., Yamagishi H. (eds) Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension. Springer, pp. 339-351, 2020
Basu A, Yoshihama M, Uechi T, Kenmochi N.
Prokaryotic ribosomal RNA stimulates zebrafish embryonic innate immune system.
BMC Res. Notes, 13, 6, 2020
2019年
Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W.
Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a.
Sci. Rep. 9(1), 18130, 2019
Uechi T, Kenmochi N.
Zebrafish models of Diamond-Blackfan anemia: A tool for understanding the disease pathogenesis and drug discovery.
Pharmaceuticals, 12(4), 151, 2019
McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D
A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS.
eLife, 8, e48847, 2019
Matsui H, Kenmochi N, Namikawa K
Age- and α-synuclein-dependent degeneration of dopamine and noradrenaline neurons in the annual killifish Nothobranchius furzeri.
Cell Rep. 26(7), 1727-1733, 2019
The RNAcentral Consortium
RNAcentral: a hub of information for non-coding RNA sequences
Nucleic Acids Res. 47(D1), D221-D229, 2019
Kurogi K, Yoshihama M, Williams FE, Kenmochi N, Sakakibara Y, Suiko M, Liu MC
Identification of zebrafish steroid sulfatase and comparative analysis of the enzymatic properties with human steroid sulfatase.
J. Steroid Biochem. Mol. Biol. 185, 110-117, 2019
2018年
Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E
De novo mutations activating germline TP53 in a novel inherited bone marrow failure syndrome.
Am. J. Hum. Genet. 103(3), 440-447, 2018
Chakraborty A, Uechi T, Nakajima Y, Gazda HT, O’Donohue MF, Gleizes PE, Kenmochi N
Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models.
Biochem. Biophys. Res. Commun. 495(2), 1839-1845, 2018
2017年
Kurogi K, Yoshihama M, Horton A, Schiefer IT, Krasowski MD, Hagey LR, Williams FE, Sakakibara Y, Kenmochi N, Suiko M, Liu MC
Identification and characterization of 5α-cyprinol-sulfating cytosolic sulfotransferases (Sults) in the zebrafish (Danio rerio).
J. Steroid. Biochem. Mol. Biol. 174, 120-127, 2017
Bao HL, Ishizuka T, Sakamoto T, Fujimoto K, Uechi T, Kenmochi N, Xu Y
Characterization of human telomere RNA G-quadruplex structures in vitro and in living cells using 19F NMR spectroscopy
Nucleic Acids Res. 45(9), 5501-5511, 2017
Ikeda F, Yoshida K, Toki T, Uechi T, Ishida S, Nakajima Y, Sasahara Y, Okuno Y, Kanezaki R, Terui K, Kamio T, Kobayashi A, Fujita T, Sato-Otsubo A, Shiraishi Y, Tanaka H, Chiba K, Muramatsu H, Kanno H, Ohga S, Ohara A, Kojima S, Kenmochi N, Miyano S, Ogawa S, Ito E
Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.
Haematologica, 102:e93-e96. 2017
Ikeda T, Nakahara A, Nagano R, Utoyama M, Obara M, Moritake H, Uechi T, Mitsui J, Ishiura H, Yoshimura J, Doi K, Kenmochi N, Morishita S, Nishino I, Tsuji S, Nunoi H
TBCD may be a causal gene in progressive neurodegenerative encephalopathy with atypical infantile spinal muscular atrophy.
J. Hum. Genet. 62, 473-480, 2017
The RNAcentral Consortium
RNAcentral: a comprehensive database of non-coding RNA sequences.
Nucleic Acids Res., 45:D128-D134. 2017
2016年
上地珠代, 剣持直哉
第2章 動物実験の対象：ゼブラフィッシュ, 第3章 動物の飼育管理・基本的手技：魚類（ゼブラフィッシュ）, 第4章 動物実験手法：ゼブラフィッシュを用いた疾患モデルの作製・解析
大・中・小動物実験プロトコル. 宮崎大学動物実験プロトコール編集委員会, 2016
剣持直哉, 吉浜麻生
第4章 snoRNA
ノンコーディングRNA－RNA分子の全体像を俯瞰する. 化学同人, 38-49, 2016
2015年
Patil P, Kibiryeva N, Uechi T, Marshall J, Artman M, O’Brien JE, Kenmochi N and Bittel DC
scaRNAs regulate splicing and vertebrate heart development.
Biochem. Biophys. Acta, 1852(8):1619-1629. 2015
Patil P, Uechi T, Kenmochi N
Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia
RNA Biology, 12(4):426-434. 2015
Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, Goi K, Matsubara K, Koike K, Ishiguro A, Okamoto Y, Watanabe K, Kanno H, Kojima S, Miyano S, Kenmochi N, Ogawa S, Ito E.
Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.
Br J Haematol, 168(6):854-864. 2015
2014年
Yamamoto T, Yamamori K, Kenmochi N, Aikawa M
A detection method for snoRNA modification domain by fully indexable dictionary retrieving
Artif Life Robotics, 19:209-214. 2014
Yadav VG, Chakraborty A, Uechi T, Kenmochi N
Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish
Int J Biochem Cell Biol, 49: 1-7. 2014
2013年
剣持直哉
リボソーム病ーリボソーム合成の異常と疾患ー
生化学：リボソームの機能調節と疾患. 85(10): 909-915. 2013
Yoshihama M, Nakao A, Kenmochi N
snOPY: a small nucleolar RNA orthological gene database
BMC Research Notes, 6: 426. 2013
山森一人，薛晨，岩切淳一，剣持直哉，吉原郁夫
構造モデルに基づく塩基配列からのboxC/D型snoRNA遺伝子検出法
情報処理学会論文誌：数理モデル化と応用 6(1): 79-89. 2013
Yamamori K, Matsuo T, Iwakiri J, Kenmochi N, Yoshihara I
A detection method for intronic snoRNA genes using extended- weight-updating SOM with appearance probability of bases
Artificial Life and Robotics, 17(3-4): 405-411. 2013
2012年
上地珠代, 剣持直哉
第1章リボソーム：リボソームタンパク質と翻訳制御
生体の科学：細胞の分子構造と機能－核以外の細胞小器官. 医学書院, 63(5): 362-363. 2012
Chakraborty A, Kenmochi N
Ribosomes and ribosomal proteins: More than just ‘housekeeping’
In: eLS 2012, John Wiley & Sons Ltd: Chichester httｐ://www.els.net/ [DOI:10.1002/9780470015902.a0005055.pub2]
剣持直哉
第18章ゲノム：イントロン
進化学事典. 共立出版, 576-579. 2012
Iwakiri J, Tateishi H, Chakraborty A, Patil P, Kenmochi N
Dissecting the protein-RNA interface: the role of protein surface shapes and RNA secondary structures in protein-RNA recognition
Nucleic Acids Res, 40(8): 3299-3306. 2012
Higa-Nakamine S, Suzuki T, Uechi T, Chakraborty A, Nakajima Y, Nakamura M, Hirano N, Suzuki T, Kenmochi N
Loss of ribosomal RNA modification causes developmental defects in zebrafish
Nucleic Acids Res, 40(1): 391-398. 2012
2011年
剣持直哉
【RNA異常による疾患】リボソーム病とp53経路
医学のあゆみ：RNA医学・医療-あらたな診断・治療を拓く. 医歯薬出版株式会社, 238(5):476-480. 2011
Chakraborty A, Uechi T, Kenmochi N
Guarding the ‘translation apparatus’: defective ribosome biogenesis and the p53 signaling pathway
WIREs RNA, 2(4): 507-522. 2011
Torihara H, Uechi T, Chakraborty A, Shinya M, Sakai N, Kenmochi N
Erythropoiesis failure due to RPS19 deficiency is independent of an activated p53 response in a zebrafish model of Diamond-Blackfan anaemia
Br J Haematol. 152(5): 648-654. 2011
Ikeda M, Andoo A, Shimono M, Takamatsu N, Taki A, Muta K, Matsushita W, Uechi T, Matsuzaki T, Kenmochi N, Takata K, Sasaki S, Ito K, Ishibashi K
The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function
J. Biol. Chem, 286(5): 3342-3350. 2011
2010年
剣持直哉
【4章】真核生物のsmall RNA
機能性RNAの分子生物学 The molecular biology of non-coding RNA. クバプロ, 111-150. 2010
2009年
比嘉三代美, 剣持直哉
ゼブラフィッシュにおけるRNA修飾の機能解析
蛋白質核酸酵素：mRNAプログラム. 54(16): 2092-2097. 2009
上地珠代, 剣持直哉
リボソーム病：翻訳装置のシステム障害
遺伝子医学MOOK：最新RNAと疾患研究. 15: 79-84. 2009
Chakraborty A, Uechi T, Higa S, Torihara H, Kenmochi N
Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apoptotic Response
PLoS ONE 4(1): e4152. 2009
2008年
Uechi T, Nakajima Y, Chakraborty A, Torihara H, Higa S, Kenmochi N
Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia.
Hum Mol Genet. 17(20): 3204-3211. 2008
剣持直哉
イントロン内在型機能性RNA遺伝子の進化
生体の科学：特集 現代医学・生物学の仮説・学説. 59(5): 386-387. 2008
2007年
Marygold S, Roote J, Reuter G, Lambertsson A, Ashburner M, Millburn M, Harrison P, Yu Z, Kenmochi N, Kaufman TC, Leevers SJ, Cook KR.
The ribosomal protein genes and Minute loci of Drosophila melanogaster.
Genome Biol. 8: R216. 2007
Nguyen HD, Yoshihama M, Kenmochi N.
The evolution of spliceosomal introns in alveolates.
Mol Biol Evol. 24(5): 1093-1096. 2007
Nguyen HD, Yoshihara I, Yamamori K, Yasunaga M.
Implementation of an effective hybrid GA for large-scale traveling salesman problems.
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics 37(1): 92-99. 2007
Yoshihama M, Nguyen HD, Kenmochi N.
Intron dynamics in ribosomal protein genes.
PLoS ONE 2(1): e141. 2007
2006年
Uechi T, Nakajima Y, Nakao A, Torihara H, Chakraborty A, Inoue K, Kenmochi N.
Ribosomal protein gene knockdown causes developmental defects in zebrafish.
PLoS ONE 1(1): e37. 2006
剣持直哉
イントロンの進化
生体の科学：生物進化の分子マップ, 57: 347-349. 2006
Nguyen HD, Yoshihama M, Kenmochi N.
Phase distribution of spliceosomal introns: implications for intron origin.
BMC Evol. Biol. 6: 69. 2006
剣持直哉
ゲノム情報に基づくsnoRNAの解析：ゼブラフィッシュを用いたアプローチ
機能性Non-coding RNA. 83-98. 2006
Yoshihama M, Nakao A, Nguyen HD, Kenmochi N.
Analysis of ribosomal protein gene structures: implications for intron evolution.
PLoS Genet. 2(3): e25. 2006
Ishii K, Washio T, Uechi T, Yoshihama M, Kenmochi N, Tomita M.
Characteristics and clustering of human ribosomal protein genes.
BMC Genomics. 7(1): 37. 2006
Maeda N, Toku S, Kenmochi N, Tanaka T.
A novel nucleolar protein interacts with ribosomal protein S19.
Biochem Biophys Res Commun. 339(1): 41-46. 2006
2005年
Nguyen HD, Yoshihama M, Kenmochi N.
New maximum likelihood estimators for eukaryotic intron evolution.
PLoS Comput Biol. 1(7): e79. 2005
2004年
Nakao A, Yoshihama M, Kenmochi N.
RPG: the Ribosomal Protein Gene database.
Nucleic Acids Res. 32(Database issue): D168-170. 2004
剣持直哉
リボソームと疾患
実験医学 増刊, 22: 200-205. 2004
2003年
Kenmochi N.
Ribosomes and Ribosomal Proteins.
In:Cooper DN (ed.) Nature Encyclopedia of the Human Genome.
Nature Publishing Group, London, 5: 77-82. 2003
剣持直哉
リボソーム病：新たな疾患としての可能性を探る
蛋白質核酸酵素 増刊号, 48: 508-516. 2003
2002年
Uechi T, Maeda N, Tanaka T, Kenmochi N.
Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes.
Nucleic Acids Res. 30(24): 5369-5375. 2002
Higa S, Maeda N, Kenmochi N, Tanaka T.
Location of 2(‘)-O-methyl nucleotides in 26S rRNA and methylation guide snoRNAs in Caenorhabditis elegans.
Biochem Biophys Res Commun. 297(5): 1344-1349. 2002
Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, Maeda N, Minoshima S, Tanaka T, Shimizu N, Kenmochi N.
The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.
Genome Res. 12(3): 379-390. 2002
2001年
Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T.
The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.
Genomics. 77(1-2): 65-70. 2001
Uechi T, Tanaka T, Kenmochi N.
A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.
Genomics. 72(3): 223-230. 2001
2000年
Ion A, Crosby AH, Kremer H, Kenmochi N, Van Reen M, Fenske C, Van Der Burgt I, Brunner HG, Montgomery K, Kucherlapati RS, Patton MA, Page C, Mariman E, Jeffery S.
Detailed mapping, mutation analysis, and intragenic polymorphism identification in candidate Noonan syndrome genes MYL2, DCN, EPS8, and RPL6.
J Med Genet. 37(11): 884-886. 2000
Kenmochi N, Yoshihama M, Higa S, Tanaka T.
The human ribosomal protein L6 gene in a critical region for Noonan syndrome.
J Hum Genet. 45(5): 290-293. 2000
剣持直哉
リボソームの分子解剖：超分子システムの遺伝子解析
バイオサイエンスとインダストリー. 58: 27-30. 2000
1999年
Higa S, Yoshihama M, Tanaka T, Kenmochi N.
Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome.
Gene. 240(2): 371-377. 1999
Kenmochi N.
Ribosomal abnormalities and human diseases.
Seikagaku. 71(3): 205-210. Review. 1999
1998年
Kenmochi N, Ashworth LK, Lennon G, Higa S, Tanaka T.
High-resolution mapping of ribosomal protein genes to human chromosome 19.
DNA Res. 5(4): 229-233. 1998
Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC.
A map of 75 human ribosomal protein genes.
Genome Res. 8(5): 509-523. 1998
1996年
Kenmochi N, Higa S, Yoshihama M, Tanaka T.
U14 snoRNAs are encoded in introns of human ribosomal protein S13 gene.
Biochem Biophys Res Commun. 228(2): 371-374. 1996