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Functional analysis of bioactive peptides

Information for Exchange Students

 

         

 

Name of the department: Department of functional analysis of bioactive peptides,FrontierScienceResearchCenter,University ofMiyazaki

Name of the research project: The role for bioactive peptides in obesity and energy metabolism

Head of the department: Yukari Date, MD, PhD

Tutor(s): Assistant Professor; Sayaka Akieda, PhD

 

Language(s): English/Japanese

Duration of the project: one month

Period of year: all year except from Dec. 25th to Jan 6th

Acceptable number of students (per period/per year): 2/period, 2/year

 

Description of the project (including, relation to the main work of the laboratory, procedures and methods used in the project):

The incidence of obesity has been fast growing in all generations during the last decade. Obesity is generally caused by ingesting calories in excess of daily requirements and is thought to contribute to the development of metabolic syndrome.

Our research group has been investigating the mechanism of feeding behavior and/or energy homeostasis, focusing on bioactive peptides, neural circuit, cross talk mechanisms of periphery with central, or cell-cell communications. Furthermore, we also developed transgenic or nerve disrupted animals relative to obesity and are investigating novel systems concerning to energy homeostasis using them.

 

The students who join us would work on our project proceeding at the term and learn some techniques such as molecular biology, cell biology, histology, and physiological experiments.

 

  1. quantitative PCR, Western blotting, DNA microarray
  2. culture of adipocytes or macrophages
  3. feeding behavior and energy metabolism of Tg or nerve disrupted animals

 

Ami of the project:

Elucidation of mechanism involved in the maintenance of energy homeostasis through in vivo and in vitro experiments.

   

Requirements (if special knowledge is needed): No special knowledge is needed.

 

Further information from:

Yukari Date