Obstetrics and Gynecology

Information for Exchange Students



Name of the department: Department of Obstetrics and Gynecology, Center for Perinatal Center, Faculty of Medicine, University of Miyazaki

Name of the research project: Clinical and basic studies on perinatal medicine and gynecologic oncology

Head of the department: Professor Hiroshi Sameshima, MD, PhD

Tutor(s): Professor Hiroshi Sameshima, MD, PhD

Associate Professor Masatoki Kaneko, MD, PhD

Associate Professor Seishi Furukawa, MD, PhD


Language(s): English/Japanese

Duration of the project: 1 – 4 weeks

Period of year: all year except Christmas holidays and summer holidays

Acceptable number of students (per period/per year): 1-2/period, 8/year


Description of the project (including, relation to the main work of the laboratory, procedures and methods used in the project):

1. Perinatal medicine. This project provides you with both clinical and basic researches. Clinical studies include 1) a population-based study on perinatal deaths and neurological damages, 2) clinical exposure in our neonatal intensive care unit to extremely premature infants, infants with severe cardiac anomalies, and other high-risk infants, 3) clinical exposure to high-risk pregnancies, especially diabetes, hypertension, thyroid malfunction, and obstetric complications such as preterm labor and premature rupture of the membranes, and 4) interpretation and management of various FHR monitoring patterns according to the fetal pathophysiology.

Basic studies are focusing on neurological damage in the developing brain in rats, which includes 1) impacts of hypoxia and inflammation, 2) impacts of prematurity, and 3) treatments with free radical scavengers, magnesium, neurotropic factors, acethylcholine, and so on.



2. Gynecologic oncology. This project offers clinical and pathological studies on uterine cancer, ovarian cancer, vulva cancer, and other gynecologic carcinomas. Surgical exposure in the OR will be offered for some students. Basic and advanced chemotherapy regimens are also open to the students, and their side effects will be studied.


The students who join our clinical studies would also learn some methods for statistical analyses, and those who join laboratory studies would learn some techniques for fetal and neonatal physiology.


Aims for the project:

         Perinatal medicine is relatively a new medical field to deal with both mother, fetus, and newborn as a unit. Perinatal exposures to environmental stimuli would change future phenotype, as known as fetal programming, that is a very attractive theory to explore. Students would learn clinical and basic approaches to this important issue.

        Gynecologic oncology is of great importance since their incidence has been increasing recently. Uterine cervical cancer is caused by viral infection, uterine corpus cancer is mainly by hormonal imbalance, and ovarian cancer is also attractive to study its oncogenesis.


Requirements (if special knowledge is needed): No special knowledge is needed, but students who are interested in clinical and basic research fields are highly recommended.


Further information from:

Contact to our foreign affair officers in Faculty of Medicine, University of Miyazaki.