Internal medicine 3 (reserch)

Information for Exchange Students



Name of the department: Neurology, Respirology, Endocrinology, and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki

Name of the research project: Elucidation of the central regulation of feeding

Head of the department: Professor Masamitsu Nakazato, MD, PhD

Tutor(s): Professor Masamitsu Nakazato, MD, PhD

        Assistant Professor Koji Toshinai, PhD

Language(s): English/Japanese

Duration of the project: One month

Period of year: all year except from Dec. 25th to Jan. 6th

Acceptable number of students (per period/per year): 1/period, 2/year



Description of the project (including, relation to the main work of the laboratory, procedures and methods used in the project): Peptide hormones or neuropeptides function as cell-to-cell signaling molecules to mediate a variety of physiological phenomena. We have been working on functional analysis of biologically active peptides, especially in the field of feeding regulation and energy homeostasis. A large array of hypothalamic neuropeptides participates in the central regulation of feeding and energy expenditure. We investigate feeding regulation to clarify the functional roles of bioactive peptides using biochemical, genetical, anatomical and pharmacological techniques.

The student(s) who joins our laboratory would work on the project proceeding at the term and learn techniques including biochemistry and molecular biology as follows.

1. Handling and behavioral analysis of experimental animals.

2. Analyses of gene expression and protein expression.

3. Analyses of animal models of diseases and transgenic animals.


Aim of the project:

         Our group has established biochemical, genetical, anatomical and pharmacological techniques to clarify the functional roles of bioactive peptides in vivo. We undertook a systematic approach to elucidate the functional roles of neuropeptides in appetite regulation and energy homeostasis.


Requirements (if special knowledge is needed): No special knowledge is needed, but students who are interested in the research field are highly recommended.


Further information from:

Koji Toshinai