宮崎大学フロンティア科学総合研究センター 生理活性物質研究部門 生理活性物質探索病態解析分野

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研究業績

発表論文：2005年～2010年

掲載日：2011年03月24日

英文原著

  1. Kuwasako K, Kitamura K, Nagata S, Hikosaka T, Kato J. Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2. Biochem Biophys Res Commun 2010; 392: 380-385
  2. Nomura I, Kato J, Tokashiki M, Kitamura K. Increased plasma levels of the mature and intermediate forms of adrenomedullin in obesity. Regul Pept 2009; 158: 127-131
  3. Kuwasako K, Kitamura K, Nagata S, Kato J. Flow cytometric analysis of the calcitonin receptor-like receptor domains responsible for cell-surface translocation of receptor activity-modifying proteins. Biochem Biophys Res Commun 2009; 384: 249-254
  4. Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. Am J Physiol Heart Circ Physiol 2009; 296: H1184-1192
  5. Nomura I, Kato J, Kitamura K. Association between body mass index and chronic kidney disease: a population-based, cross-sectional study of a Japanese community. Vasc Health Risk Manag 2009; 5: 315-320
  6. Masuyama H, Tsuruda T, Sekita Y, Hatakeyama K, Imamura T, Kato J, Asada Y, Stasch JP, Kitamura K. Pressure-independent effects of pharmacological stimulation of soluble guanylate cyclase on fibrosis in pressure-overloaded rat heart. Hypertens Res 2009; 32: 597-603
  7. Ashizuka S, Inagaki-Ohara K, Kuwasako K, Kato J, Inatsu H, Kitamura K. Adrenomedullin treatment reduces intestinal inflammation and maintains epithelial barrier function in mice administered dextran sulphate sodium. Microbiol Immunol 2009; 53: 573-581
  8. Kuwasako K, Kitamura K, Nagata S, Kato J. Functions of the extracellular histidine residues of receptor activity-modifying proteins vary within adrenomedullin receptors. Biochem Biophys Res Commun 2008; 377: 109-113
  9. Tsuruda T, Kato J, Hatakeyama K, Kojima K, Yano M, Yano Y, Nakamura K, Nakamura-Uchiyama F, Matsushima Y, Imamura T, Onitsuka T, Asada Y, Nawa Y, Eto T, Kitamura K. Adventitial mast cells contribute to pathogenesis in the progression of abdominal aortic aneurysm. Circ Res 2008; 102: 1368-1877
  10. Jessup JA, Trask AJ, Chappell MC, Nagata S, Kato J, Kitamura K, Ferrario CM. Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats. Am J Physiol Heart Circ Physiol 2008; 294: H2614-H2618
  11. Tsuruda T, Kato J, Sumi T, Mishima K, Masuyama H, Nakao H, Imamura T, Eto T, Kitamura K. Combined use of brain natriuretic peptide and C-reactive protein for predicting cardiovascular risk in outpatients with type 2 diabetes mellitus. Vasc Health Risk Manag 2007; 3: 1-7
  12. Kato J, Kitamura K, Eto T. Plasma adrenomedullin level and development of hypertension. J Hum Hypertens 2006; 20: 566-570
  13. Nagata S, Kato J, Sasaki K, Minamino N, Eto T, Kitamura K. Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system. Biochem Biophys Res Commun 2006; 350: 1026-1031
  14. Tsuruda T, Kato J, Hatakeyama K, Yamashita A, Nakamura K, Imamura T, Kitamura K, Onitsuka T, Asada Y, Eto T. Adrenomedullin in mast cells of abdominal aortic aneurysm. Cardiovasc Res 2006; 70: 158-164
  15. Masuyama H, Tsuruda T, Kato J, Imamura T, Asada Y, Stasch JP, Kitamura K, Eto T. Soluble guanylate cyclase stimulation on cardiovascular remodeling in angiotensin II-induced hypertensive rats. Hypertension 2006; 48: 972-978
  16. Kuwasako K, Cao YN, Chu CP, Iwatsubo S, Eto T, Kitamura K. Functions of the cytoplasmic tails of the human receptor activity-modifying protein components of calcitonin gene-related peptide and adrenomedullin receptors. J Biol Chem 2006; 281: 7205-7213
  17. Kato J, Etoh T, Kitamura K, Eto T. Atrial and brain natriuretic peptides as markers of cardiac load and volume retention in primary aldosteronism. Am J Hypertens 2005; 18: 354-357
  18. Tsuruda T, Kato J, Hatakeyama K, Masuyama H, Cao YN, Imamura T, Kitamura K, Asada Y, Eto T. Antifibrotic effect of adrenomedullin on coronary adventitia in angiotensin II-induced hypertensive rats. Cardiovasc Res 2005; 65: 921-929
  19. Tsuruda T, Kato J, Matsui E, Hatakeyama K, Masuyama H, Imamura T, Kitamura K, Asada Y, Eto T. Adrenomedullin alleviates not only neointimal formation but also perivascular hyperplasia following arterial injury in rats. Eur J Pharmacol 2005; 508: 201-204
  20. Ashizuka S, Ishikawa N, Kato J, Yamaga J, Inatsu H, Eto T, Kitamura K. Effect of adrenomedullin administration on acetic acid-induced colitis in rats. Peptides 2005; 26: 2610-2615
  21. Cao YN, Kuwasako K, Kato J, Yanagita T, Tsuruda T, Kawano J, Nagoshi Y, Chen AF, Wada A, Suganuma T, Eto T, Kitamura K. Beyond vasodilation: the antioxidant effect of adrenomedullin in Dahl salt-sensitive rat aorta. Biochem Biophys Res Commun 2005; 332: 866-872
  22. Cao YN, Kuwasako K, Kato J, Nishihira K, Asada Y, Eto T, Kitamura K: Overexpression of proadrenomedullin N-terminal 20 peptide blunts blood pressure rise and attenuates myocardial hypertrophy and fibrosis in hypertensive rats. FEBS Lett 2005; 579: 4997-5001
  23. Onitsuka H, Imamura T, Yamaga J, Kuwasako K, Kitamura K, Eto T. Angiotensin II stimulates cardiac adrenomedullin production and causes accumulation of mature adrenomedullin independently of hemodynamic stress in vivo. Horm Metab Res 2005; 37: 281-285

英文総説・著書

  1. Kato J, Kitamura K, Eto T. Roles of adrenomedullin in hypertension and hypertensive organ damage. Curr Hypertens Rev 2006; 2: 283-295
  2. Kato J, Tsuruda T, Kita T, Kitamura K, Eto T. Adrenomedullin: a protective factor for blood vessels. Arterioscler Thromb Vasc Biol 2005: 25: 2480-2487
  3. Kato J, Eto T. Role of adrenomedullin in cardiovascular diseases. Nishikimi T (ed), Adrenomedullin in Cardiovascular Disease, Springer, New York, 131-154, 2005

邦文総説・著書

  1. 加藤丈司．アドレノメデュリン．日本臨牀．67(Suppl 6): 208-211, 2009
  2. 加藤丈司．JSH 2009：高血圧治療ガイドライン改訂のポイント．宮崎県内科医会誌 75: 2-5, 2009
  3. 桑迫健二、加藤丈司、北村和雄.　アドレノメデュリン遺伝子．日本臨牀．67(Suppl 6): 400-404, 2009
  4. 加藤丈司、芦塚伸也、鶴田敏博、桑迫健二、北村和雄．アドレノメデュリンの基礎と新たな可能性．循環器科 64: 448-455, 2008
  5. 加藤丈司．高齢者高血圧における脳卒中予防のための降圧薬選択．モダンフィジシャン 28: 1544-1545, 2008
  6. 加藤丈司．降圧治療におけるACE阻害薬とARBの併用の是非．モダンフィジシャン 28: 1671, 2008
  7. 永田さやか、加藤丈司、北村和雄．プロアンジオテンシン-12．分子心血管病．9(3): 288-292, 2008
  8. 永田さやか、加藤丈司、北村和雄．アンジオテンシン関連の新たな内在性ペプチド：プロアンジオテンシン-12．循環器科．64(5): 496-502, 2008
  9. 加藤丈司． 外来における降圧薬選択：Ca拮抗薬かARBか．Medical Practice 24: 1452, 2007
  10. 加藤丈司、北村和雄、江藤胤尚．高血圧の生化学検査　アドレノメデュリン．血圧 13: 225-227, 2006
  11. 加藤丈司、江藤胤尚． 低血圧．杉本恒明、矢崎義雄編、内科学 (第九版）、朝倉書店、東京、638-640, 2007
  12. 加藤丈司、北村和雄．循環器疾患とアドレノメデュリン．寒川賢治、南野直人編、ペプチドと創薬、メディカルドゥ、大阪、116-119, 2007
  13. 加藤丈司、江藤胤尚．降圧薬投与開始は単剤か併用か．日本臨牀 64(Suppl 6): 254-257, 2006
  14. 加藤丈司、江藤胤尚．高血圧治療薬．新薬展望 2006、医薬ジャーナル社、大阪、257-263, 2006
  15. 桑迫健二、北村和雄.　カルシトニン遺伝子関連ペプチド(CGRP).　CLINICAL CALCIUM 16: 21-28, 2006
  16. 加藤丈司、北村和雄、江藤胤尚．心血管に対するストレスと降圧因子アドレノメデュリン．適応医学 9: 30-36, 2005
  17. 加藤丈司、北村和雄、江藤胤尚．生理活性物質と血圧調節異常：アドレノメデュリンと血圧調節異常．Molecular Medicine 42: 234-237, 2005
  18. 加藤丈司、北村和雄．アドレノメデュリンの測定と血中濃度．ホルモンと臨床 53: 269-274, 2005
  19. 加藤丈司、江藤胤尚．JSH 2004に基づく高血圧の実地診療の実際．Medical Practice 22: 1846-1854, 2005
  20. 桑迫健二、北村和雄.　アドレノメデュリン受容体の薬理学的特徴および病態生理学的意義.　分子心血管病 6: 25-32, 2005
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