Original Articles (1996-2000)

  1. Kataoka, H., Meng, J-Y., Itoh, H., Hamasuna, R., Shimomura, T., Suganuma, T., Koono, M.: Localization of hepatocyte growth factor activator inhibitor type 1 in Langhans' cells of human placenta. Histochem. Cell Biol., 114:469-475 (2000)
  2. Kataoka, H., Shimomura, T., Kawaguchi, T., Hamasuna, R., Itoh, H., Kitamura, N., Miyazawa, K., Koono, M.: Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment. J. Biol. Chem., 275:40453-40462 (2000)
  3. Itoh, H., Yamauchi, M., Kataoka, H., Hamasuna, R., Kitamura, N., Koono, M.: Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genes. Eur. J. Biochem., 267:3351-3359 (2000)
  4. Kataoka, H., Hamasuna, R., Itoh, H., Kitamura, N., Koono, M.: Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma. Cancer Res., 60: 6148-6159 (2000)
  5. Nabeshima K., Inoue, T., Shimao, Y., Okada, Y., Itoh, Y., Seiki, M., Koono, M.: Front cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor. Cancer Res., 60:3364-3369 (2000)
  6. Itoh, H., Hamasuna, R., Kataoka, H., Yamauchi, M., Miyazawa, K., Kitamura, N., Koono, M.: Mouse hepatocyte growth factor activator gene: its expression not only in the liver but also in the gastrointestinal tract. Biochim. Biophys. Acta, 1491:295-302 (2000)
  7. Yanagita, T., Kobayashi, H., Yamamoto, R., Kataoka, H., Yokoo, H., Shiraishi, S., Minami, S., Koono, M., Wada, A.: Protein kinase C-Eand -Edown-regulate cell surface sodium channels via differential mechanisms in adrenal chromaffin cells. J. Neurochem., 74:1674-1684 (2000)
  8. Kinoshita, K., Taupin, D.R., Itoh, H., Podolsky, D.K.: Distinct pathways of cell migration and antiapoptotic response to epithelial injury: sturcutre-function analysis of human intestinal trefoil factor. Mol. Cell. Biol., 20:4680-4690 (2000)
  9. Ikeda, T., Murata, Y., Quilligan, E.J., Parer, J.T., Murayama, T., Koono, M.: Histologic and biochemical study of the brain, heart, kidney, and liver in asphyxia caused by occlusion of the umbilical cord in near-term fetal limbs. Am. J. Obstet. Gynecol., 182:449-457 (2000)
  10. Sameshima, T., Nabeshima, K., Toole, B.P., Yokogami, K., Okada, Y., Goya, T., Koono, M., Wakisaka, S.: Expression of EMMPRIN (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int. J. Cancer, 88:21-27 (2000)
  11. Sameshima, T., Nabeshima, K., Toole, B.P., Yokogami, K., Okada, Y., Goya, T., Koono, M., Wakisaka, S.: Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. Cancer Lett., 157:177-184 (2000)
  12. Tomita, M., Kobayashi, T., Itoh, H., Onitsuka, T., Nawa, Y.: Goblet cell hyperplasia in the airway of Nippostrongylus brasiliensis-infected rats. Respiration, 67:565-569 (2000)
  13. Kataoka, H., Itoh, H., Uchino, H., Hamasuna, R., Kitamura, N., Nabeshima, K., Koono, M.: Conserved expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin in human colorectal carcinomas. Cancer Lett., 148:127-134 (2000)
  14. Itoh, H., Kataoka, H., Tomita, M., Hamasuna, R., Nawa, Y., Kitamura, N., Koono, M.: Up-regulation of hepatocyte growth factor activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa. Am. J. Physiol. Gastrointest. Liver Physiol., 278: G635-G643 (2000)
  15. Uchino, H., Kataoka, H., Itoh, H., Hamasuna, R., Koono, M.: Overexpression of intestinal trefoil factor in human colon carcinoma cells reduces cellular growth in vitro and in vivo. Gastroenterology, 118: 60-69 (2000)
  16. Hamasuna, R., Kataoka, H., Moriyama, T., Itoh, H., Seiki, M., Koono, M.: Regulation of matrix metalloproteinase-2 (Gelatinase A/72kDa type IV collagenase) expression and activity by hepatocyte growth factor/scatter factor in a human glioma cell lines. Int. J. Cancer, 82: 274-281 (1999).
  17. Moriyama, T., Kataoka, H., Hamasuna, R., Yoshida, E., Sameshima, T., Iseda, T., Yokogami, K., Nakano, S., Koono, M., Wakisaka, S.: Simultaneous up-regulation of urokinase-type plasminogen activator (uPA) and uPA receptor by hepatocyte growth factor/scatter factor in human glioma cells. Clin. Exp. Metastasis, 17:873-879 (1999).
  18. Seguchi, K., Kataoka, H., Uchino, H., Nabeshima, K., Koono, M.: Secretion of protease nexin-II/amyloid Eprotein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors. Biol. Chem., 380: 473-483 (1999).
  19. Kataoka, H., Suganuma, T., Shimomura, T., Itoh, H., Kitamura, N., Nabeshima, K., Koono, M.: Distribution of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in human tissues: cellular surface localization of HAI-1 in simple columnar epithelium and its modulated expression in injured and regenerative tissues. J. Histochem. Cytochem., 47: 673-682 (1999).
  20. Kataoka, H., Uchino, H., Iwamura, T, Seiki, M., Nabeshima, K., Koono, M.: Enhanced tumor growth and invasiveness in vivo by a carboxy-terminal fragment of E-proteinase inhibitor generated by matrix metalloproteinase: A possible modulatory role in natural killer cytotoxicity. Am. J. Pathol., 154: 457-468 (1999).
  21. Itoh, H., Kataoka, H., Hamasuna, R., Kitamura, N., Koono, M.: Hepatocyte growth factor activator inhibitor type 2 lacking the first Kunitz-type serine proteinase inhibitor domain is a predominant product in mouse but not in human. Biochem. Biophys. Res. Commun., 255: 740-748 (1999).
  22. Itoh, H., Inoue, N., Podolsky, D.K.: Goblet-cell specific transcription of mouse intestinal trefoil factor gene results from collaboration of complex series of positive and negative regulatory elements. Biochem. J., 341:461-472 (1999).
  23. Itoh, H., Beck, P.L., Inoue, N., Xavier, R., Podolsky, D.K.: A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells. J. Clin. Invest., 104:1539-1547 (1999).
  24. Inoue T., Nabeshima, K., Shimao, Y., Koono, M.: Hepatocyte growth factor/scatter factor (HGF/SF) is a regulator of fibronectin splicing in MDCK cells: Comparison between the effects of HGF/SF and TGF-E on fibronectin splicing at the EDA region. Biochem. Biophys. Res. Commun., 260:225-231 (1999).
  25. Shimao, Y., Nabeshima, K., Inoue, T., Koono, M.: Role of fibroblasts in HGF/SF-induced cohort migration of human colorectal carcinoma cells: Fibroblasts stimulate migration associated with increased fibronectin production via upregulated TGFR-E. Int. J. Cancer, 82:449-458 (1999).
  26. Shimao, Y., Nabeshima, K., Inoue, T., Koono, M.: TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: Selective role of PKC-ƒΏ and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotide treatment. Clin. Exp. Metastasis, 17:351-360 (1999).
  27. Sato, Y., Kataoka, H., Asada, Y., Marutsuka, K., Kamikubo, Y., Koono, M., Sumiyoshi, A.: Overexpression of tissue factor pathway inhibitor in aortic smooth muscle cells inhibits cell migration induced by tissue factor/factor VIIa complex. Thromb. Res., 94: 401-406 (1999).
  28. Uehara, H., Kawano H., Kataoka, H., Sameshima, T., Moriyama, T., Nakano, S., Wakisaka, S.: Mutational analysis of human p53 gene in human gliomas by Cleavase fragment length polymorphism. Neuropathology, 19: 267-272 (1999).
  29. Tomita, M., Itoh, H., Kobayashi, T., Onitsuka, T., Nawa, Y.: Expression of mast cell proteases in rat lung during helminth infection: Mast cells express both rat mast cell protease II and tryptase in helminth infected lung. Int. Arch. Allergy Immunol., 120:303-309 (1999).
  30. Ide, H., Itoh, H., Yoshida, E., Kobayashi, T., Tomita, M., Maruyama, H., Osada, Y., Nakahata, T., Nawa, Y.: Immunohistochemical demonstration of inter-ƒΏ-trypsin inhibitor light chanin (bikunin) in huma mast cells. Cell Tissue Res., 297:149-154 (1999).
  31. Nabeshima, K., Shimao, Y., Inoue, T., Itoh, H., Kataoka, H., Koono, M.: Hepatocyte growth factor/scatter factor (HGF/SF) induce not only scattering but also cohort migration of human colorectal adenocarcinoma cells. Int. J. Cancer, 78: 750-759 (1998).
  32. Moriyama, T., Kataoka, H., Hamasuna, R., Yokogami, K., Uehara, H., Kawano, H., Goya, T., Tsubouchi, H., Koono, M., Wakisaka, S.: Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. Biochem. Biophys. Res. Commun., 249: 73-77 (1998).
  33. Nabeshima, K., Inoue,T., Shimao,Y., Kataoka,H., Koono,M.: TPA-induced cohort migration of well differentiated human rectal adenocarcinoma cells: Cells move in a RGD-dependent manner on fibronectin produced by cells, and phosphorylation of E-cadherin/catenin complex is induced independent of cell-extracellular matrix interactions. Virchows Archiv., 433:243-253 (1998).
  34. Hatakeyama, K., Asada, Y., Marutsuka, K., Kataoka, H., Sato, Y., Sumiyoshi, A.: Expression of tissue factor in the rabbit aorta after balloon injury. Atherosclerosis, 139: 265-271 (1998).
  35. Inoue,T., Nabeshima,K., Shimao,Y., Kataoka, H., Koono, M.: Cell density- dependent regulation of fibronectin splicing at the EDA region in fibroblasts: Cell density also modulates the responses of fibroblasts to TGF- and cancer cell-conditioned medium. Cancer Lett., 129: 45-54 (1998).
  36. Kataoka, H., Uchino, H., Denda, K., Kitamura, N., Itoh, H., Tsubouchi, H., Nabeshima, K., Koono, M.: Evaluation of hepatocyte growth factor activator inhibitor expression in normal and malignant colonic mucosa. Cancer Lett., 128: 219-227 (1998).
  37. Moriyama,T., Kataoka,H., Kawano,H., Yokogami,K.,Nakano,S., Goya,T., Uchino,H., Koono,M., Wakisaka,S.: Comparative analysis of expression of hepatocyte growth factor and its receptor, c-met, in gliomas, meningiomas and shwannomas in humans. Cancer Lett., 124: 149-155 (1998).
  38. Yokogami, K., Kawano, H., Uchinokura, S., Moriyama, T., Uehara, H., Sameshima, T., Goya, T., Wakisaka, S., Nabeshima, K., Nagamachi, S., Jinnouchi, S.: Characteristics pattern of Tl-201 chloride and 99mMIBI uptake in a pineocytoma. Clin. Nucl. Med., 23:771-773 (1998).
  39. Uhino, H., Kataoka, H., Itoh, H., Koono, M.: Expression of intestinal trefoil factor mRNA is down-regulated during progression of colorectal carcinomas. J. Clin. Pathol., 50: 932-934 (1997).
  40. Nabeshima, K., Shimao, Y., Sato, S., Kataoka, H., Moriyama, T., Kawano, H., Wakisaka, S., Koono, M.: Expression of c-Met correlates with grade of malignancy in human astrocytic tumors: An immunohistochemical study. Histopathology, 31: 436-443 (1997).
  41. Kataoka, H., Uchino, H., Asada, Y., Hatakeyama, K., Nabeshima, K., Sumiyoshi, A., Koono, M.: Analysis of tissue factor and tissue factor pathway inhibitor expression in human colorectal carcinoma cell lines and metastatic sublines to the liver. Int. J. Cancer, 72: 878-884 (1997).
  42. Hatakeyama, S., Gao Y. H., Ohara-Nemoto, Y., Kataoka, H., Satoh, M.: Expression of bone morphogenic proteins of human neoplastic epithelial cells. Biochem. Mol. Biol. Int., 42: 497-505 (1997).
  43. Moriyama,T., Kataoka,H., Seguchi,K., Nabeshima,K., Kawano,H., Goya,T., Wakisaka,S., Ohgami,A., Suzumiya,J., Kikuchi, M., Koono,M.: Establishment and characterization of a new human glioblastoma cell line (MGM-1) with highly motile phenotype. Hum. Cell, 10:105-110 (1997).
  44. Kataoka, H., Meng, J-Y. Uchino, H., Nabeshima, K., Kihira, Y., Matsuo, Y., Koono, M.: Modulation of matrix metalloproteinase-7 (matrilysin) secretion in co-culture of human colon carcinoma cells with fibroblasts from orthotopic and ectopic organs. Oncol. Res., 9:101-109 (1997).
  45. Nabeshima, K., Asada, Y., Inoue, T., Kataoka, H., Shimao, Y., Sumiyoshi, A., Koono, M.: Modulation of E-cadherin expression in TPA- induced cell motility: Well-differentiated human adenocarcinoma cells move as coherent sheets associated with phosphorylation of E-cadherin-catenin complex. Lab. Invest., 76:139-151 (1997).
  46. Murayama, T., Zuber, C., Seelentag, W.K.F., Li, W-P., Kemmner, W., Heitz, P.U., Roth, J.: Colon carcinoma glycoproteins carrying ƒΏ2,6-linked sialic acid reactive with Sambucus nigra agglutinin are not constitutively expressed in normal human colon mucosa and are distinct from sialyl-TN antigen. Int. J. Cancer, 70:575-581 (1997).
  47. Itoh, H., Tomita, M., Uchino, H., Kobayashi, T., Kataoka, H., Sekiya, R., Nawa, Y.: cDNA cloning of rat pS2 peptide and expression of trefoil peptides in acetic acid-induced colitis. Biochem. J., 318:939-944 (1996).
  48. Inoue, T., Nabeshima, K., Kataoka, H., Koono, M.: Feasibility of archival non-buffered formalin-fixed and paraffin-embedded tissues for PCR amplification: An analysis of resected gastric carcinoma. Pathol. Int., 46:997-1004 (1996).
  49. Inoue, T., Nabeshima, K., Shimao, Y., Kataoka, H., Koono, M.: Modulation of fibronectin synthesis by cancer cell-fibroblast interaction: Cancer cells stimulate fibronectin production and affect alternative splicing of fibronectin pre-mRNA at EDA region in fibroblasts. Int. J. Oncol., 9: 721-730 (1996).
  50. Decastro, R., Zhang, H., Guo, H., Kataoka, H., Gordon, M.K., Toole, B.P., Biswas, C.: Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer. J. Invest. Dermatol., 106:1260-1265 (1996).
  51. Moriyama, T., Kataoka, H., Seguchi, K., Tsubouchi, H., Koono, M.: Effects of heptocyte growth factor (HGF) on glioma cells in vitro ; HGF acts as a motility factor in glioma cells. Int. J. Cancer, 66:678-685 (1996).