2024
【原著】
N. Choijookhuu, K. Yano, B. Lkham-Erdene, S. Shirouzu, T. Kubota, Fidya, T. Ishizuka, K. Kai, E. Chosa, Y. Hishikawa, HMGB2 promotes de novo lipogenesis to accelerate hepatocyte proliferation during liver regeneration. J Histochem Cytochem. 2024, in press. doi: 10.1369/00221554241241569.
Ikenoue M, Choijookhuu N, Yano K, Fidya, Takahashi N, Ishizuka T, Shirouzu S, Yamaguma Y, Kai K, Higuchi K, Sawaguchi A, Nanashima A, Hishikawa Y. The crucial role of SETDB1 in structural and functional transformation of epithelial cells during regeneration after intestinal ischemia reperfusion injury. Histochem Cell Biol. 2024 Jan 13. doi: 10.1007/s00418-023-02263-9.
Kai K, Nakashima K, Kawakami H, Takeno S, Hishikawa Y, Ikenoue M, Hamada T, Imamura N, Shibata T, Noritomi T, Sasaki F, Nakamura Y, Nanashima A. Clinical Impact of the Charlson Comorbidity Index on the Efficacy of Salvage Photodynamic Therapy Using Talaporfin Sodium for Esophageal Cancer. Intern Med. 2024 Apr 1;63(7):903-910. doi: 10.2169/internalmedicine.1907-23.
Fidya, Choijookhuu N, Ikenoue M, Yano K, Yamaguma Y, Shirouzu S, Kai K, Ishizuka T, Hishikawa Y. Protective role of estrogen through G-protein coupled receptor 30 in a colitis mouse model. Histochem Cell Biol. 2024 Jan;161(1):81-93. doi: 10.1007/s00418-023-02235-z.【学位論文】
2023
【原著】
Nagai T, Sekimoto T, Kurogi S, Ohta T, Miyazaki S, Yamaguchi Y, Tajima T, Chosa E, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Sato K, Hishikawa Y, Funamoto T. Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway. Sci Rep. 2023 Sep 5;13(1):14639. doi: 10.1038/s41598-023-41837-4.【学位論文】
Uto T, Fukaya T, Mitoma S, Nishikawa Y, Tominaga M, Choijookhuu N, Hishikawa Y, Sato K. Clec4A4 Acts as a Negative Immune Checkpoint Regulator to Suppress Antitumor Immunity. Cancer Immunol Res. 2023 Sep 1;11(9):1266-1279. doi: 10.1158/2326-6066.CIR-22-0536.
Nakamura T, Sakaguchi H, Mohri H, Ninoyu Y, Goto A, Yamaguchi T, Hishikawa Y, Matsuda M, Saito N, Ueyama T. Dispensable role of Rac1 and Rac3 after cochlear hair cell specification. J Mol Med. 2023 Jul;101(7):843-854. doi: 10.1007/s00109-023-02317-4.
Fukaya T, Uto T, Mitoma S, Takagi H, Nishikawa Y, Tominaga M, Choijookhuu N, Hishikawa Y, Sato K. Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells. Cell Rep. 2023 May 30;42(5):112431. doi: 10.1016/j.celrep.2023.112431.
Kai K, Hiyoshi M, Imamura N, Hamada T, Yano K, Sato Y, Sakae T, Komi M, Nakamura T, Choijookhuu N, Hishikawa Y, Nanashima A. A Preliminary Pathological Evaluation of Extracellular Volume Fraction with Contrast-enhanced Computed Tomography as a Novel Quantitative Parameter of Pancreatic Fibrosis. Intern Med. 2023;62(8):1107-1115. doi: 10.2169/internalmedicine.0410-22.
Kai K, Hamada T, Sato Y, Hiyoshi M, Imamura N, Yano K, Ikeda T, Ichihara A, Ogata S, Choijookhuu N, Hishikawa Y, Hosokawa A, Nanashima A. Extracellular Volume Fraction Calculated Using Contrast-Enhanced Computed Tomography as a Biomarker of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome: A Preliminary Histopathological Analysis. J Oncol. 2023 Feb 14;2023:1440257. doi: 10.1155/2023/1440257.【学位論文】
【総説】
石塚 匠, Narantsog Choijookhuu, 柴田 恭明, 小路 武彦, 菱川 善隆. 蛍光共鳴エネルギー移動(FRET)現象を利用した 高感度 in situ hybridization. 顕微鏡 2023, 58(3), 117-122.
菱川 善隆, Narantsog Choijookhuu, 石塚 匠, 柴田恭明, 小路武彦. In situ hybridization法. 組織細胞化学. 177-187, 2023. 日本組織細胞化学会(編), 中西印刷
【賞】
2023年度（第25回）日本組織細胞化学会論文賞
Choijookhuu N, Shibata Y, Ishizuka T, Xu Y, Koji T, Hishikawa Y. An advanced detection system for in situ hybridization using a fluorescence resonance energy transfer–based molecular beacon probe. Acta Histochem. Cytochem. 2022, 55, 119-128. doi: 10.1267/ahc.22-00075.
2022
【原著】
Shirouzu S, Sugita N, Choijookhuu N, Yamaguma Y, Takeguchi K, Ishizuka T, Tanaka M, Fidya, Kai K, Chosa E, Yamashita Y, Koshimoto C and Hishikawa Y. Pivotal role of High-Mobility Group Box 2 in ovarian folliculogenesis and fertility. J Ovarian Res. 2022, 15, 133. doi: 10.1186/s13048-022-01071-4.【学位論文】
He Z, Ishizuka T, Hishikawa Y, Xu Y. Click chemistry for fluorescence imaging via combination of a BODIPY-based ‘turn-on’ probe and a norbornene glucosamine. Chem. Commun. 2022, 58, 12479-12482. doi:10.1039/D2CC05359D.
Choijookhuu N, Shibata Y, Ishizuka T, Xu Y, Koji T, Hishikawa Y. An advanced detection system for in situ hybridization using a fluorescence resonance energy transfer–based molecular beacon probe. Acta Histochem. Cytochem. 2022, 55, 119-128. doi: 10.1267/ahc.22-00075.
Yano K, Choijookhuu N, Ikenoue M, Fidya, Fukaya T, Sato K, Lee D, Taniguchi N, Chosa E, Nanashima A, Hishikawa Y. Spatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration. Sci. Rep. 2022 12:11962. doi: 10.1038/s41598-022-16258-4.【学位論文】
Miyazaki S, Funamoto T, Sekimoto T, Kurogi S, Ohta T, Nagai T, Tajima T, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Hishikawa Y, Chosa E. EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation. Acta Histochem. Cytochem. 2022 55(3):99-110. doi: 10.1267/ahc.22-00027.【学位論文】
Yamaguma Y, Sugita N, Choijookhuu N, Yano K, Lee D, Ikenoue M, Fidya, Shirouzu S, Ishizuka T, Tanaka M, Yamashita Y, Chosa E, Taniguchi N, Hishikawa Y. Crucial role of high-mobility group box 2 in mouse ovarian follicular development through estrogen receptor beta. Histochem. Cell Biol. 2022 157:359–369 doi: 10.1007/s00418-022-02074-4.【学位論文】
Hishikawa Y, Takizawa T, Koji T. In focus in HCB: new histochemical insights into mammalian gametogenesis. Histochem. Cell Biol. 2022 157(3):269-271. doi: 10.1007/s00418-022-02083-3.
【総説】
菱川善隆, Narantsog Choijookhuu, 石塚匠, 柴田恭明, 小路武彦.: がんの分子病理学（序論）解析法 1.FISH・ISH. 病理と臨床【臨時増刊号】・別刷 2022 vol.40. 41-46, 東京／文光堂／本郷
菱川 善隆, Narantsog Choijookhuu, 石塚 匠, 柴田恭明, 小路武彦. In situ hybridization法. 組織細胞化学. 111-120, 2022. 日本組織細胞化学会(編), 中西印刷
2021
【原著】
Sugita N, Choijookhuu N, Yano K, Lee D, Ikenoue M, Fidya, Taniguchi N, Chosa E, Hishikawa Y. Depletion of HMGB2 causes seminiferous tubule atrophy via aberrant expression of androgen and estrogen receptors in mouse testis. Biol. Reprod. 2021 105:1510-1520. doi: 10.1093/biolre/ioab187.【学位論文】
Congenital Deficiency of Conventional Dendritic Cells Promotes the Development of Atopic Dermatitis-Like Inflammation. Front Immunol. 2021 Jul 27;12:712676. doi: 10.3389/fimmu.2021.712676. eCollection 2021.
In situ strategy for biomedical target localization via nanogold nucleation and secondary growth. Commun. Biol. 2021 4:710. doi: 10.1038/s42003-021-02246-3.
【著書】
菱川善隆, 柴田恭明, 小路武彦.: in situ hybridization法の原理と応用. 組織細胞化学 2021. 107-120, 2021. 日本組織細胞化学会(編), 中西印刷
2020
【原著】
Miyanaga N, Takagi H, Uto T, Fukaya T, Nasu J, Fukui T, Nishikawa Y, Sparwasser T, Choijookhuu N, Hishikawa Y, Nakamura T, Tono T, and Sato K.: Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy. Commun. Biol. 2020 3(1):742. doi: 10.1038/s42003-020-01466-3.
Mai NNH, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, Sato K, Tuan LQ, Hishikawa Y.: Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells. Acta Histochem. Cytochem. 2020, 53 (4) 61-72 DOI: 10.1267/ahc.20-00002 【学位論文】
Fukui T, Fukaya T, Uto T, Takagi H, Nasu J, Miyanaga N, Nishikawa Y, Koseki H, Choijookhuu N, Hishikawa Y, Yamashita Y, Sato K.: Pivotal Role of CD103 in the Development of Psoriasiform Dermatitis. Sci. Rep. 2020 May 20;10(1):8371. doi: 10.1038/s41598-020-65355-9
Diep NV, Choijookhuu N, Fuke N, Myint O, Izzati UZ, Suwanruengsri M, Hishikawa Y, Yamaguchi R.: New Tropisms of Porcine Epidemic Diarrhoea Virus (PEDV) in Pigs Naturally Coinfected by Variants Bearing Large Deletions in the Spike (S) Protein and PEDVs Possessing an Intact S Protein. Transbound. Emerg. Dis. 2020 May DOI: 10.1111/tbed.13607【学位論文】
【著書】
菱川善隆, 柴田恭明, 小路武彦.: in situ hybridization法の原理と応用. 組織細胞化学 2020. 107-121, 2020. 日本組織細胞化学会(編), 中西印刷
【賞】
2020年度（第22回）日本組織細胞化学会論文賞
Kyaw MTH, Yamaguchi Y, Choijookhuu N, Yano K, Takagi H, Takahashi N, Oo PS, Sato K, Hishikawa Y.: The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells. Acta Histochem. Cytochem. 2019, 52:1-8
2020年度（第22回）日本組織細胞化学会論文賞
Oo PS, Yamaguchi Y, Sawaguchi A, Kyaw MTH, Choijookhuu N, Ali MN, Srisowanna N, Hino SI, Hishikawa Y.: Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells. Acta Histochem. Cytochem. 2018, 51:21-31
2019
【原著】
Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W.: Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a. Scientific Reports 2019, doi.org/10.1038/s41598-019-54544-w
Phyu KP, Zin PW, Aung MN, Lar MM, Hishikawa Y, Maruyama M, Yokota H, Thant KZ, Wai KT, Yano Y.: Contamination of arsenic in drinking water in Ayeyarwady delta region, Myanmar. World Journal of Pharmaceutical and Life Sciences. 2019, 5(8):42-48
Srisowanna N, Choijookhuu N, Yano K, Batmunkh B, Ikenoue M, Mai NNH, Yamaguchi Y and Hishikawa Y.: The effect of estrogen on hepatic fat accumulation during early phase of liver regeneration after partial hepatectomy in rats. Acta Histochem. Cytochem. 2019, 52 (4)1-9 doi.org/10.1267/ahc.19018【学位論文】
Mochizuki H, Phyu KP, Aung MN, Zin PW, Yano Y, Myint MZ, Thit WM, Yamamoto Y, Hishikawa Y, Thant KZ, Maruyama M, Kuroda Y.: Peripheral neuropathy induced by drinking water contaminated with low-dose arsenic in Myanmar. Environ Health Prev Med. 2019 Apr 23;24(1):23. doi: 10.1186/s12199-019-0781-0.
Kyaw MTH, Yamaguchi Y, Choijookhuu N, Yano K, Takagi H, Takahashi N, Oo PS, Sato K, Hishikawa Y.: The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells. Acta Histochem. Cytochem. 2019, 52:1-8 【学位論文】
【著書】
菱川善隆, 柴田恭明, 小路武彦.: in situ hybridizationの最前線 －技術の最前線の状況と研究・診断への応用－. 病理と臨床Vol. 37, No.11: 1139-1144,文光堂, 2019
菱川善隆：In situ hybridization (RNA) の基礎と応用．組織細胞化学 2019. 83-99, 2019. 日本組織細胞化学会(編), 学際企画．
2018
【原著】
Fukaya T, Fukui T, Uto T, Takagi H, Nasu J, Miyanaga N, Arimura K, Nakamura T, Koseki H, Choijookhuu N, Hishikawa Y, Yamashita Y, Sato K.: Pivotal role of IL-22BP in the epithelial autoregulation of IL-22 signaling in the control of skin inflammation. Frontiers. Immunol. 2018 Jun 21;9:1418. doi: 10.3389/fimmu.2018.01418. eCollection 2018
Lee D, Taniguchi N, Sato K, Choijookhuu N, Hishikawa Y, Kataoka H, Morinaga H, Lotz M Chosa E.: HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles. Sci. Rep. 2018, doi:10.1038/s41598-018-28023 【学位論文】
Ali MN, Choijookhuu N, Takagi H, Srisowanna N, Huynh MNH, Yamaguchi Y, Oo PS, Kyaw MTH, Sato K, Yamaguchi R, Hishikawa Y.: The HDAC Inhibitor, SAHA, Prevents Colonic Inflammation by Suppressing Pro-inflammatory Cytokines and Chemokines in DSS-induced Colitis. Acta Histochem. Cytochem. 2018, 51:33-40【学位論文】
Oo PS, Yamaguchi Y, Sawaguchi A, Kyaw MTH, Choijookhuu N, Ali MN, Srisowanna N, Hino SI, Hishikawa Y.: Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells. Acta Histochem. Cytochem.2018, 51:21-31【学位論文】
Uto T, Takagi H, Fukaya T, Nasu J, Fukui T, Miyanaga N, Arimura K, Nakamura T, Choijookhuu N, Hishikawa Y, Katsuaki Sato.: Critical role of plasmacytoid dendritic cells in induction of oral tolerance. Journal of Allergy and Clinical Immunology. 2018 141:2156-2167
【著書】
菱川善隆：In situ hybridization の原理と基礎．組織細胞化学 2018. 135-146, 2018. 日本組織細胞化学会(編), 中西印刷．
2017
【原著】
Matsumoto J, Suzuki K, Yasuda M, Yamaguchi Y, Hishikawa Y, Imamura N, Nanashima A.: Photodynamic therapy of human biliary cancer cell line using combination of phosporus porphyrins and light emitting diode. Bioorg. Med. Chem. 2017, 25:6536-6541
Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N.: Novel role of Rac-Mid1 signaling in medial cerebellar development. Development. 2017, 144:1863-1875
Honda A, Choijookhuu N, Izu H, Kawano Y, Inokuchi M, Honsho K, Lee AR, Nabekura H, Ohta H, Tsukiyama T, Ohinata Y, Kuroiwa A, Hishikawa Y, Saitou M, Jogahara T, Koshimoto C.: Flexible adaptation of male germ cells from female iPSCs of endangered Tokudaia osimensis. Sci Adv. 2017 May 12;3(5):e1602179. doi: 10.1126/sciadv.1602179
Honda A, Kawano Y, Izu H, Choijookhuu N, Honsho K, Nakamura T, Yabuta Y, Yamamoto T, Takashima Y, Hirose M, Sankai T, Hishikawa Y, Ogura A, Saitou M.: Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naïve Conversion. Sci Rep. Mar 28;7:45285. 2017 doi: 10.1038/srep45285
Batmunkh B, Choijookhuu N, Srisowanna N, Byambatsogt U, Oo PS, Ali MN, Yamaguchi Y, Hishikawa Y.: Estrogen accelerates cell proliferation through estrogen receptor alpha during rat liver regeneration after partial hepatectomy. Acta Histochem. Cytochem. 2017, 50:39-48 【学位論文】
Tsuchiya K, Ikeda T, Batmunkh B, Choijookhuu N, Ishizaki H, Hotokezaka M, Hishikawa Y Nanashima A.: Frequency of CD4+CD161+ T cell and interleukin-10 expression in inflammatory bowel diseases. Acta Histochem. Cytochem. 2017, 50:21-28 【学位論文】
【著書】
菱川善隆：In situ hybridization 法ー基礎編．組織細胞化学 2017. 159-169, 2017. 日本組織細胞化学会(編), 中西印刷．
2016
【原著】
Chayapong J, Madhyastha H, Madhyastha R, Nurrahmah QI, Nakajima Y, Choijookhuu N, Hishikawa Y, Maruyama M.: Arsenic trioxide induces ROS activity and DNA damage, leading to G0/G1 extension in skin fibroblasts through the ATM-ATR-associated Chk pathway. Environ Sci Pollut Res Int. 2016 Dec 24. DOI 10.1007/s11356-016-8215-7 【学位論文】
Arimura K, Takagi H, Uto T, Fukaya T, Nakamura T, Choijookhuu N, Hishikawa Y, Yamashita Y, Sato K.: Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation Mucosal Immunol. 2016, 10:957-970. 【学位論文】
Takagi H, Arimura K, Uto T, Fukaya T, Nakamura T, Choijookhuu N, Hishikawa Y, Sato K.: Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation. Sci Rep. 2016; 6: 24477. doi: 10.1038/srep24477
Yamaguchi Y, Madhyastha H, Madhyastha R, Choijookhuu N, Hishikawa Y, Pengjam Y, Nakajima Y, Maruyama M.: Arsenic acid inhibits proliferation of skin fibroblasts, and increases cellular senescence through ROS mediated MST1-FOXO signaling pathway. J Toxicol Sci. 2016; 41: 105-113. 【学位論文】
【総説】
菱川善隆：遺伝子の局在を見る― in situ hybridization. Clinical Neuroscience. 2016 Vol. 34, No.6
Choijookhuu N, Hino SI, Oo PS, Batmunkh B, Hishikawa Y.: The role of estrogen receptors in intestinal homeostasis and disease. Receptors Clin Investig. 2016 Vol 3, No 1; doi: 10.14800/rci.1109
2015
【著書】
菱川善隆：In situ hybridization 法の原理と基礎．組織細胞化学 2015. 77-91, 2015.日本組織細胞化学会（編），中西印刷．
【総説】
Hino SI, Choijookhuu N, Hishikawa Y. 形態科学を基盤とした遺伝子発現解析法-in situ hybridization法を中心に. 顕微鏡Vol. 50, No. 1, 2015
【原著】
Muraoka I, Takatsuki M, Sakai Y, Tomonaga T, Soyama A, Hidaka M, Hishikawa Y, Koji T, Utoh R, Ohashi K, Okano T, Kanematsu T, Eguchi S.: Transplanted fibroblast cell sheets promote migration of hepatic progenitor cells in the incised host liver in allogenic rat model. J Tissue Eng Regen Med. 11:E108-115, 2015.
Choijookhuu N, Hino SI, Oo PS, Batmunkh B, Ali MN, Kyaw MTH, Hishikawa Y.: Ontogenetic changes in the expression of estrogen receptor β in mouse duodenal epithelium. Clin Res Hepatol Gastroenterol. 39, 499-507, 2015
2014
【原著】
Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, Koji T, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N.: Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells. J Cell Sci. 127:2040–2052, 2014
Nakajima K, Shibata Y, Hishikawa Y, Suematsu T, Mori M, Fukuhara S, Koji T, Sawase T, Ikeda T.: Coexpression of Ang1 and Tie2 in Odontoblasts of Mouse Developing and Mature Teeth-A New Insight into Dentinogenesis. Acta Histochem. Cytochem. 47: 19–25, 2014
2013
【著書】
菱川善隆：In situ hybridization 法の原理と基礎．組織細胞化学：2013. 63-76, 2013.日本組織細胞化学会（編），中西印刷．
【総説】
菱川善隆：形態科学を基盤とした遺伝子・タンパク質の発現・機能解析法の実際．宮崎医会誌 37:79-87, 2013
2012
【原著】
An S, Soe K, Akamatsu M, Hishikawa Y, Koji T.: Accelerated proliferation of hepatocytes in rats with iron overload after partial hepatectomy. Histochem Cell Biol.138: 773-786, 2012.
Choijookhuu N, Sato Y, Nishino T, Endo D, Hishikawa Y, Koji T.: Estrogen-dependent regulation of sodium/hydrogen exchanger-3 (NHE3) expression via estrogen receptor β in proximal colon of pregnant mice. Histochem Cell Biol.137:575-587,2012.
Kitamura M, Nishino T, Obata Y, Furusu A, Hishikawa Y, Koji T, Kohno S.: Epigallocatechin gallate suppresses peritoneal fibrosis in mice. Chemico-Biological Interactions 195: 95-104, 2012.
2011
【原著】
Song N, Liu J, An S, Nishino T, Hishikawa Y, Koji T.: Immunohistochemical analysis of histone H3 modifications in germ cells during mouse spermatogenesis. Acta Histochem. Cytochem. 44:183-190, 2011.
【著書】
菱川善隆：１章 形態学的検出法．２節 光学顕微鏡－免疫組織化学．実験医学別冊 細胞死実験プロトコール：30-41, 2011．刀祢重信，小路武彦（編），羊土社．
菱川善隆，小路武彦：17．In situ hybridization．病気の分子形態学：66-69, 2011．日本臨床分子形態学会（編），学際企画．
2010
【原著】
Yamamoto-Fukuda T, Hishikawa Y, Shibata Y, Kobayashi T, Takahashi H, Koji T.: Pathogenesis of middle ear cholesteatoma; a new model of experimentally induced cholesteatoma in mongolian gerbils. Am. J. Pathol. 176:2602-2606, 2010.
Abo T, Nagayasu T, Hishikawa Y, Tagawa T, Nanashima A, Yamayoshi T, Matsumoto K, An S, Koji T.: Expression of keratinocyte growth factor and its receptor in rat tracheal cartilage: Possible involvement in wound healing of the damaged cartilage. Acta Histochem. Cytochem. 43:89-98, 2010.
Kakugawa T, Mukae H, Hishikawa Y, Ishii H, Sakamoto N, Ishimatsu Y, Fujii T, Koji T, Kohno S.: Localization of HSP47 mRNA in murine bleomycin-induced pulmonary fibrosis. Virchows Archiv. 456:309-315, 2010.
Yamamoto-Fukuda T, Takahashi H, Terakado M, Hishikawa Y, Koji T.: Expression of keratinocyte growth factor and its receptor in noncholesteatomatous and cholesteatomatous chronic otitis media. Otol. Neurotol. 31:745-751, 2010.
Tokunaga T, Naruke Y, Shigematsu S, Kohno T, Yasui K, Ma Y, Chua KJ, Katayama I, Nakamura T, Hishikawa Y, Koji T, Yatabe Y, Nagayasu T, Fujita T, Matsuyama T, Hayashi H.: Aberrant expression of interferon regulatory factor 3 in human lung cancer. Biochem. Biophys. Res. Commun. 397:202-207, 2010.
【著書】
菱川善隆，小路武彦：B. In situ ハイブリダイゼーション In situハイブリダイゼーションの基礎と応用．組織細胞化学2010：47-60, 2010．日本組織細胞化学会（編），学際企画.
【総説】
小路武彦，菱川善隆：病理学的遺伝子解析（in situ hybridization, in situ PCR, およびHELMET）．日本臨床 68（増刊号8）:219-226, 2010.
2009
【原著】
Matsumoto K, Nagayasu T, Hishikawa Y, Tagawa T, Yamayoshi T, Abo T, Tobinaga S, Furukawa K, Koji T.: Keratinocyte growth factor accelerates compensatory growth in the remaining lung after trilobectomy in rats. J. Thorac. Cardiovasc. Surg. 137:1499-1507, 2009.
Shirendeb U, Hishikawa Y, Moriyama S, Win N, Thu MMM, Mar KS, Khatanbaatar G, Masuzaki H, Koji T.: Human papillomavirus infection and its possible correlation with p63 expression in cervical cancer in Japan, Mongolia, and Myanmar. Acta Histochem. Cytochem. 42:181-190, 2009.
Hishikawa Y, An S, Yamamoto-Fukuda T, Shibata Y, Koji T.: Improvement of in situ PCR by optimization of PCR cycle number and proteinase K concentration: Localization of X chromosome-linked phosphoglycerate kinase-1 gene in mouse reproductive organs. Acta Histochem. Cytochem. 42:15-21, 2009.
【著書】
菱川善隆：第8章 精巣の病理学．永遠の不死－精子形成細胞の生物学：97-116, 2009．小路武彦（編），サイエンス社.
2008
【原著】
Yamamoto-Fukuda T, Terakado M, Hishikawa Y, Koji T, Takahashi H.: Topical application of 5-fluorouracil on attic cholesteatoma results in downregulation of keratinocyte growth factor and reduction of proliferative activity. Eur. Arch. Otorhinolaryngol. 265:1173-1178, 2008.
Koji T, Kondo S, Hishikawa Y, An S, Sato Y.: In situ detection of methylated DNA by histo endonuclease-linked detection of methylated DNA sites: a new principle of analysis of DNA methylation. Histochem. Cell Biol. 130:917-925, 2008.
Nagai K, Jinnai I, Hata T, Usui T, Sasaki D, Tsukasaki K, Sugahara K, Hishikawa Y, Yamada Y, Tanaka Y, Koji T, Mano H, Kamihira S, Tomonaga M.: Adhesion-dependent growth of primary adult T cell leukemia cells with down-regulation of HTLV-1 p40Tax protein: a novel in vitro model of the growth of acute ATL cells. Int. J. Hematol. 88:551-564, 2008.
Nakagawa T, Kajitani T, Togo S, Masuko N, Ohdan H, Hishikawa Y, Koji T, Matsuyama T, Ikura T, Muramatsu M, Ito T.: Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation. Gene Dev. 22:37-49, 2008.
【著書】
菱川善隆，小路武彦：B. In situ ハイブリダイゼーション法．In situハイブリダイゼーションの基礎と応用．組織細胞化学2008：35-49, 2008．日本組織細胞化学会（編），学際企画.
2007
【原著】
Jimbo R, Sawase T, Shibata Y, Hirata K, Hishikawa Y, Tanaka Y, Bessho K, Ikeda T, Atsuta M.: Enhanced osseointegration by the chemotactic activity of plasma fibronectin for cellular fibronectin positive cells. Biomaterials 28:3469-3477, 2007.
An S, Hishikawa Y, Liu J, Koji T.: Lung injury after ischemia-reperfusion of small intestine in rats involves apoptosis of type II alveolar epithelial cells mediated by TNF-α and activation of Bid pathway. Apoptosis 12:1989-2001, 2007.
Mochizuki K, Ohno Y, Kanematsu T, Sakurai-Yamashita Y, Niwa M, Hishikawa Y, Koji T.: Possible protection of sinusoidal endothelial cells by endothelin B receptor during hepatic warm ischemia-reperfusion. Surg. Today 37:460-467, 2007.
Matsuo Y, Nomata K, Eguchi J, Aoki D, Hayashi T, Hishikawa Y, Kanetake H, Shibata Y, Koji T.: Immunohistochemical analysis of connexin43 expression in infertile human testes. Acta Histochem. Cytochem. 40:69-75, 2007.
Soe K, Hishikawa Y, Fukuzawa Y, Win N, Yin KS, Win KM, Myint AA, Koji T.: Possible correlation between iron deposition and enhanced proliferating activity in hepatitis C virus-positive hepatocellular carcinoma in Myanmar (Burma). J. Gastroenterol. 42:225-235, 2007.
【著書】
小路武彦，江島邦明，菱川善隆：第12章 ヒトの発生・遺伝・老化．ビジュアル解剖生理学：365-384, 2007．藤本 淳（監修），ヌーヴェルヒロカワ.
2006
【原著】
Ulziibat S, Ejima K, Shibata Y, Hishikawa Y, Kitajima M, Fujishita A, Ishimaru T, Koji T.: Identification of estrogen receptor β-positive intraepithelial lymphocytes and their possible roles in normal and tubal pregnancy oviducts. Hum. Reprod. 21:2281-2289, 2006.
Mapendano CK, Kishino T, Miyazaki K, Kondo S, Yoshiura K, Hishikawa Y, Koji T, Niikawa N, Ohta T.: Expression of the Snurf-Snrpn IC transcript in the oocyte and its putative role in the imprinting establishment of the mouse 7C imprinting domain. J. Hum. Genet. 51:236-243, 2006.
Shukuwa K, Izumi S, Hishikawa Y, Ejima K, Inoue S, Muramatsu M, Ouchi Y, Kitaoka T, Koji T.: Diethylstilbestrol increases the density of prolactin cells in male mouse pituitary by inducing proliferation of prolactin cells and transdifferentiation of gonadotropic cells. Histochem. Cell Biol. 126:111-123, 2006.
【著書】
柴田恭明，菱川善隆，池田 通，小路武彦：第5章 mRNA検出のためのin situハイブリダイゼーション．染色・バイオイメージング実験ハンドブック：111-120, 2006．高田邦昭，齋藤尚亮，川上速人（編），羊土社.
菱川善隆，小路武彦：第6章 サウスウェスタン組織化学．染色・バイオイメージング実験ハンドブック：189-194, 2006．高田邦昭，齋藤尚亮，川上速人（編），羊土社.
2005
【原著】
Iwanaga H, Matsumoto T, Enomoto H, Okano K, Hishikawa Y, Shindo H, Koji T.: Enhanced expression of insulin-like growth factor-binding proteins in human osteoarthritic cartilage detected by immunohistochemistry and in situ hybridization. Osteoarthr. Cartilage 13:439-448, 2005.
An S, Hishikawa Y, Koji T.: Induction of cell death in rat small intestine by ischemia reperfusion: differential roles of Fas/Fas ligand and Bcl-2/Bax systems depending upon cell types. Histochem. Cell Biol. 123:249-261, 2005.
Shirota K, Tateishi K, Koji T, Hishikawa Y, Hachisuga T, Kuroki M, Kawarabayashi T.: Early human preantral follicles have relaxin and relaxin receptor (LGR7), and relaxin promotes their development. J. Clin. Endocrinol. Metab. 90:516-521, 2005.
Hira E, Ono T, Dhar DK, El-Assal ON, Hishikawa Y, Yamanoi A, Nagasue N.: Overexpression of macrophage migration inhibitory factor induces angiogenesis and deteriorates prognosis after radical resection for hepatocellular carcinoma. Cancer 103:588-598, 2005.
Fukushima C, Matsuse H, Hishikawa Y, Kondo Y, Machida I, Saeki S, Kawano T, Tomari S, Obase Y, Shimoda T, Koji T, Kohno S.: Pranlukast, a leukotriene receptor antagonist, inhibits interleukin-5 production via a mechanism distinct from leukotriene receptor antagonism. Int. Arch. Allergy Immunol. 136:165-172, 2005.
Sun F, Kawasaki E, Akazawa S, Hishikawa Y, Sugahara K, Kamihira S, Koji T, Eguchi K.: Apoptosis and its pathway in early post-implantation embryos of diabetic rats. Diabetes Res. Clin. Pract. 67:110-118, 2005.
2004
【原著】
Aoki D, Yamamoto-Fukuda T, Hishikawa Y, Nakamura M, Sakai H, Kanetake H, Koji T.: Coexpression of keratinocyte growth factor and its receptor in normal and prostate cancer tissues: possible formation of autonomous andromedin loop. Acta Histochem. Cytochem. 37:379-389, 2004.
Hishikawa Y, Tamaru N, Ejima K, Hayashi T, Koji T.: Expression of keratinocyte growth factor and its receptor in human breast cancer: its inhibitory role in the induction of apoptosis possibly through the overexpression of Bcl-2. Arch. Histol. Cytol. 67:455-464, 2004.
Tamaru N, Hishikawa Y, Ejima K, Nagasue N, Inoue S, Muramatsu M, Hayashi T, Koji T.: Estrogen receptor-associated expression of keratinocyte growth factor and its possible role in the inhibition of apoptosis in human breast cancer. Lab. Invest. 84:1460-1471, 2004.
Kawano N, Koji T, Hishikawa Y, Murase K, Murata I, Kohno S.: Identification and localization of estrogen receptor α- and β-positive cells in adult male and female mouse intestine at various estrogen levels. Histochem. Cell Biol. 121:399-405, 2004.
Yamayoshi T, Nagayasu T, Matsumoto K, Abo T, Hishikawa Y, Koji T.: Expression of keratinocyte growth factor/fibroblast growth factor-7 and its receptor in human lung cancer: correlation with tumour proliferative activity and patient prognosis. J. Pathol. 204:110-118, 2004.
【著書】
菱川善隆，小路武彦：IV．Southwestern Histochemistryの理論と実際的応用．組織細胞化学2004：111-118, 2004．日本組織細胞化学会（編），学際企画.
2003
【原著】
Tsurusaki T, Aoki D, Kanetake H, Inoue S, Muramatsu M, Hishikawa Y, Koji T.: Zone-dependent expression of estrogen receptors α and β in human benign prostatic hyperplasia. J. Clin. Endocrinol. Metab. 88:1333-1340, 2003.
Ueda S, Yamanoi A, Hishikawa Y, Dhar DK, Tachibana M, Nagasue N.: Transforming growth factor-β 1 released from the spleen exerts a growth inhibitory effect on liver regeneration in rats. Lab. Invest. 83:1595-1603, 2003.
Nonaka MI, Hishikawa Y, Moriyama N, Koji T, Ogata RT, Kudo A, Kawakami H, Nonaka M.: Complement C4b-binding protein as a novel murine epididymal secretory protein. Biol. Reprod. 69:1931-1939, 2003.
Okada K, Nakashima M, Komuta K, Hashimoto S, Okudaira S, Baba N, Hishikawa Y, Koji T, Kanematsu T, Watanabe T.: Expression of tumor-associated membrane antigen, RCAS1, in human colorectal carcinomas and possible role in apoptosis of tumor-infiltrating lymphocytes. Mod. Path. 16: 679-685, 2003.
Imaizumi Y, Murota H, Kanda S, Hishikawa Y, Koji T, Taguchi T, Tanaka Y, Yamada Y, Ikeda S, Kohno T, Yamamoto K, Mori N, Tomonaga M, Matsuyama T.: Expression of the c-Met proto-oncogene and its possible involvement in liver invasion in adult T-cell leukemia. Clin. Cancer Res. 9:181-187, 2003.
Yamamoto-Fukuda T, Aoki D, Hishikawa Y, Kobayashi T, Takahashi H, Koji T.: Possible involvement of keratinocyte growth factor and its receptor in enhanced epithelial-cell proliferation and acquired recurrence of middle-ear cholesteatoma. Lab. Invest. 83:123-136, 2003.
【著書】
Koji T, Izumi S, Hishikawa Y.: Molecular histochemistry of rRNAs by nonradioactive in situ hibyridization at light- and electron-microscopic levels. In: Advancement of Life Science:141-146, 2003. Setsu, Roan(eds). Amvo Publishing Company.
Hishikawa Y, Izumi S, Koji T.: Southwestern histochemical analysis of estrogen responsive element in paraffin-embedded tissue sections of mouse ovary. In: Advancement of Life Science:147-152, 2003. Setsu, Roan(eds). Amvo Publishing Company.
Izumi S, Takano K, Hishikawa Y, Koji T.: In situ hybridization of prolactin mRNA in rat pituitary sections: Backscattered electron mode analysis using light microscopic specimen on glass slides. In: Advancement of Life Science:153-158, 2003. Setsu, Roan(eds). Amvo Publishing Company.
An S, Hishikawa Y, Koji T.: Induction of apoptosis in the crypts of rat small intestine by ischemia-reperfusion. In: Advancement of Life Science:159-164, 2003. Setsu, Roan(eds). Amvo Publishing Company.
【総説】
菱川善隆，小路武彦：In situ hybridizationによるゲノム転写物の局在証明と定量的解析．細胞 35：489-493, 2003.
Koji T, Hishikawa Y.: Germ cell apoptosis and its molecular trigger in mouse testes. Arch. Histol. Cytol. 66:1-16, 2003.
Hishikawa Y, Damavandi E, Izumi S, Koji T.: Molecular histochemical analysis of estrogen receptor α and β expressions in the mouse ovary: In situ hybridization and Southwestern histochemistry. Med. Electron Microsc. 36:67-73, 2003.
2002
【原著】
Damavandi E, Hishikawa Y, Izumi S, Shin M, Koji T.: Involvement of Bax redistribution in the induction of germ cell apoptosis in neonatal mouse testes. Acta Histochem. Cytochem. 35:449-459, 2002.
Kondo T, Goto S, Ihara Y, Urata Y, Ikeda S, Hishikawa Y, Izumi S, Shin M, Koji T.: Diethylstilbestrol attenuates antioxidant activities in testis from male mice. Free Radic. Res. 36:957-966, 2002.
Shibata Y, Hishikawa Y, Izumi S, Fujita S, Yamaguchi A, Koji T.: Involvement of Fas/Fas ligand in the induction of apoptosis in chronic sialadenitis of minor salivary glands including Sjögren’s Syndrome. Hum. Cell 15:52-60, 2002.
【総説】
Shin M, Hishikawa Y, Izumi S, Koji T.: Southwestern histochemistry as a molecular histochemical tool for analysis of expression of transcription factors: Application to paraffin embedded tissue sections. Med. Electron Microsc. 35:217-224, 2002.
末松貴史，和泉伸一，進 正志，菱川善隆，田口 尚，小路武彦：電顕ISHによる核内RNAの局在検討．電子顕微鏡 37:92-95, 2002.
和泉伸一，菱川善隆，進 正志，小路武彦：アポトーシスの形態学的特徴．最新医学 57:2454-2459, 2002.
2001
【原著】
Koji T, Hishikawa Y, Ando H, Nakanishi Y, Kobayashi N.: Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis. Biol. Reprod. 64:946-954, 2001.
Hishikawa Y, Kohno H, Ueda S, Kimoto T, Dhar DK, Kubota H, Tachibana M, Koji T, Nagasue N.: Expression of metallothionein in colorectal cancers and synchronous liver metastases. Oncology 61:162-167, 2001.
Sawada T, Koji T, Hishikawa Y, Kishimoto K, Nagayasu T, Takahashi T, Oka T, Ayabe H.: Partial tolerance of subcutaneously transplanted xenogeneic tumour cell graft by Fas-mediated immunosuppression. Immunology 103:81-89, 2001.
Izumi S, Shin M, Hishikawa Y, Koji T.: Immunoelectron microscopic identification of tRNA on ribosome particles in rat liver and placenta. J. Electr. Microsc. Technol. Med. Biol. 15:72-75, 2001.
【総説】
菱川善隆，小路武彦：in situ PCR法．細胞 33:196-199, 2001.
Izumi S, Shin M, Hishikawa Y, Koji T.: Localization in situ of specific RNA by light and electron microscopy. Ital. J. Anat. Embryol. 106:45-50, 2001.
2000
【原著】
Yamamoto-Fukuda T, Shibata Y, Hishikawa Y, Shin M, Yamaguchi A, Kobayashi T, Koji T.: Effects of various decalcification protocols on detection of DNA strand breaks by terminal dUTP nick end labelling. Histochem. J. 32:697-702, 2000.
Sutoh I, Kohno H, Nakashima Y, Hishikawa Y, Tabara H, Tachibana M, Kubota H, Nagasue N.: Concurrent expressions of metallothionein, glutathione-S-transferase-π and P-glycoprotein in colorectal cancers. Dis. Colon Rectum 43:221-232, 2000.
【著書】
菱川善隆，小路武彦： In situ hybridization 3. mRNA in situ hybridizationの基本的技法 2)放射性プローブと非放射性プローブの比較．免疫組織化学とin situ hybridizationのすべて 病理と臨床Vol. 18. 臨時増刊号：252-257, 2000. 長村義之，笹野公伸（編），文光堂.
Hishikawa Y, Murakami M, Kasahara M, Nagasue N.:Chapter 11 In situ hybridization for RNA: Nonradioactive probe: Oligo-DNA probe: T-T dimer. In: Molecular Histochemical Techniques:153-171, 2000. Koji(ed), Springer.
【総説】
和泉伸一，進 正志，菱川善隆，小路武彦：免疫組織化学およびサウスウェスタン組織化学の電顕技術．医学生物学電子顕微鏡技術学会誌 15:64-69, 2000.
1999
【原著】
Tachibana M, Tabara H, Kotoh T, Kinugasa S, Dhar DK, Hishikawa Y, Masunaga R, Kubota H, Nagasue N.: Prognostic significance of perioperative blood transfusions in resectable thoracic esophageal cancer. Am. J. Gastroenterol. 94:757-765, 1999.
Hishikawa Y, Koji T, Dhar DK, Kinugasa S, Yamaguchi M, Nagasue N.: Metallothionein expression correlates with metastatic and proliferative potential in squamous cell carcinoma of the oesophagus. Br. J. Cancer 81:712-720, 1999.
Monden N, Abe S, Hishikawa Y, Yoshimura H, Kinugasa S, Dhar DK, Tachibana M, Nagasue N.: The role of P-glycoprotein in human gastric cancer xenografts in response to chemotherapy. Int. J. Surg. Investig. 1:3-10, 1999.
1998
【原著】
Kinugasa S, Abe S, Tachibana M, Hishikawa Y, Yoshimura H, Monden N, Dhar DK, Nagasue N.: Overexpression of transforming growth factor-β1 in scirrhous carcinoma of the stomach correlates with decreased survival. Oncology 55:582-587, 1998.
【著書】
菱川善隆：第二章 IV. パラフィン切片のin situ hybridization．In situ hybridization技法：164-171, 1998．小路武彦（編），学際企画.
1997
【原著】
Monden N, Abe S, Sutoh I, Hishikawa Y, Kinugasa S, Nagasue N.: Prognostic significance of the expressions of metallothionein, glutathione-S-transferase-π, and P-glycoprotein in curatively resected gastric cancer. Oncology 54:391-399, 1997.
Hishikawa Y, Abe S, Kinugasa S, Yoshimura H, Monden N, Igarashi M, Tachibana M, Nagasue N.: Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer. Oncology 54: 342-347, 1997.
Yamaguchi M, Yu L, Hishikawa Y, Yamanoi A, Kubota H, Nagasue N.: Growth kinetic study of human hepatocellular carcinoma using proliferating cell nuclear antigen and Lewis Y antigen: their correlation with transforming growth factor-α and β 1. Oncology 54:245-251, 1997.
1996
【原著】
Kinugasa S, Tachibana M, Hishikawa Y, Abe S, Yoshimura H, Monden N, Dhar DK, Nagasue N.: Prognostic significance of proliferating cell nuclear antigen (PCNA) in squamous cell carcinoma of the esophagus. Jpn. J. Clin. Oncol. 26:405-410, 1996.
1993
【症例報告】
菱川善隆, 五十嵐雅彦, 松尾 進, 中村輝久: 食道アカラシアに合併した後天性全結腸hypoganglionosisの一例 -酵素抗体法による免疫組織化学的検討-. 日本小児外科学会雑誌 29:1273-1276, 1993.
【総説】
久保田博文, 五十嵐雅彦, 深澤公朗, 菱川善隆, 松尾 進, 末永直文, 中村輝久：乳癌に対する乳房温存手術28例の経験．乳癌の臨床 8:270-274, 1993.