Wada Laboratory

Structural Biology

Introduction

Our research focuses on the molecular mechanisms of systems involving dynamic structural changes in proteins. With X-ray crystallography as our core technique, we utilize molecular biology, biochemistry, and spectroscopy to visualize complex molecular mechanisms.

Our research policy is to "never compromise by relying solely on predictions based on structural information, but to insist thoroughly on experimental verification." Although many of our projects are still works in progress...

  • News
  • At the 109th Congress of the Japanese Society of Legal Medicine (June 11–13, 2025): Our student, Ms. Miu Tachibana, received the Excellent Student Presentation Award!! 👏👏

    At the Japanese Biochemical Society Kyushu Branch Meeting (June 13–14, 2025): Our students—Mr. Marukawa, Mr. Uchida, and Mr. Mizumoto—presented posters. Mr. Uchida received the Best Poster Award!! 👏👏

    Research topics of Wada Laboratory

  • Iron-Sulfur Cluster Biosynthesis System
  • Proteins containing cofactors known as Fe-S clusters are ubiquitous in the biological world and are responsible for universal metabolic processes such as respiration and photosynthesis.....

     
  • Glutathione Degrading Enzymes
  • Glutathione (GSH; γ-Glu-Cys-Gly), an essential antioxidant for living organisms, possesses a specific peptide bond (γ-glutamyl linkage) via the glutamate side chain.....

  • Red Tide Viruses
  • We aim to elucidate the host recognition mechanisms of natural marine viruses that control the collapse of harmful algal blooms (red tides).....

  • Synthesis and Degradation of Photosynthetic Pigments
  • In photosynthetic organisms such as red algae and cyanobacteria, tetrapyrrole pigments exist in photosynthetic or light-harvesting apparatuses. Efficient photosynthesis is only possible when these function correctly.....

  • Photosensor Proteins
  • Cyanobacteria are the earliest photosynthetic organisms and possess phycobilisomes as light-harvesting antennae. Many cyanobacteria.....

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