■原著論文

1. Tsuruda T, Kato J, Matsui E, Hatakeyama K, Masuyama H, Imamura T, Kitamura K, Asada Y, Eto T. Adrenomedullin alleviates not only neointimal formation but also perivascular hyperplasia following arterial injury in rats. Eur J Pharmacol. 2005; 508: 201-4.

2. Furukoji E, Matsumoto M, Yamashita A, Yagi H, Sakurai Y, Marutsuka K, Hatakeyama K, Morishita K, Fujimura Y, Tamura S, Asada Y. Adenovirus-mediated transfer of human placental ectonucleoside triphosphate diphosphohydrolase to vascular smooth muscle cells suppresses platelet aggregation in vitro and arterial thrombus formation in vivo. Circulation. 2005; 111: 808-15.

3. Hatakeyama K, Hao H, Imamura T, Ishikawa T, Shibata Y, Fujimura Y, Eto T, Asada Y. Relation of CD39 to plaque instability and thrombus formation in directional atherectomy specimens from patients with stable and unstable angina pectoris. Am J Cardiol. 2005; 95: 632-5.

4. Tsuruda T, Kato J, Hatakeyama K, Masuyama H, Cao YN, Imamura T, Kitamura K, Asada Y, Eto T. Antifibrotic effect of adrenomedullin on coronary adventitia in angiotensin II-induced hypertensive rats. Cardiovasc Res. 2005; 65: 921-9.

5. Sato Y, Hatakeyama K, Yamashita A, Marutsuka K, Sumiyoshi A, Asada Y. Proportion of fibrin and platelets differs in thrombi on ruptured and eroded coronary atherosclerotic plaques in humans. Heart 2005; 91: 526-30.

6. Kosuge M, Kimura K, Kojima S, Sakamoto T, Matsui K, Ishihara M, Asada Y, Tei C, Miyazaki S, Sonoda M, Tsuchihashi K, Yamagishi M, Ikeda Y, Shirai M, Hiraoka H, Inoue T, Saito F, Ogawa H; on behalf of the Japanese Acute Coronary Syndrome Study (JACSS) Investigators. Effects of glucose abnormalities on in-hospital outcome after coronary intervention for acute myocardial infarction. Circ J. 2005; 69: 375-9.

7. Arakawa H, Qian JY, Baatar D, Karasawa K, Asada Y, Sasaguri Y, Miller ER, Witztum JL, Ueno H. Local expression of platelet-activating factor-acetylhydrolase reduces accumulation of oxidized lipoproteins and inhibits inflammation, shear stress-induced thrombosis, and neointima formation in balloon-injured carotid arteries in nonhyperlipidemic rabbits. Circulation. 2005; 111: 3302-9.

8. Tajima T, Yoshida E, Yamashita A, Ohmura S, Tomitaka Y, Sugiki M, Asada Y, Maruyama M. Hemoglobin stimulates the expression of matrix metalloproteinases, MMP-2 and MMP-9 by synovial cells: a possible cause of joint damage after intra-articular hemorrhage. J Orthop Res. 2005; 23: 891-8.

9. Cao YN, Kuwasako K, Kato J, Nishihira K, Asada Y, Eto T, Kitamura K. Overexpression of proadrenomedullin N-terminal 20 peptide blunts blood pressure rise and attenuates myocardial hypertrophy and fibrosis in hypertensive rats. FEBS Lett. 2005; 579: 4997-5001.

10. Uchikawa Y, Okano M, Sawada A, Asada Y, Kobayashi H, Wada A, Nao-i N, Ohkura M, Tanaka N, Yamamoto R. Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions. Clin Exp Pharmacol Physiol. 2005; 32: 675-80.

11. Sun H, Koike T, Ichikawa T, Hatakeyama K, Shiomi M, Zhang B, Kitajima S, Morimoto M, Watanabe T, Asada Y, Chen YE, Fan J. C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. Am J Pathol. 2005; 167: 1139-48.

12. Ishihara M, Kojima S, Sakamoto T, Asada Y, Tei C, Kimura K, Miyazaki S, Sonoda M, Tsuchihashi K, Yamagishi M, Ikeda Y, Shirai M, Hiraoka H, Inoue T, Saito F, Ogawa H; Japanese Acute Coronary Syndrome Study Investigators. Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era. Am Heart J. 2005; 150: 814-20.

13. Frank RD, Schabbauer G, Holscher T, Sato Y, Tencati M, Pawlinski R, Mackman N: The synthetic pentasaccharide fondaparinux reduced coagulation, inflammation and neutrophil accumulation in kidney ischemia-reperfusion injury. J Thromb Haemost 2005; 3: 531-40.

■著書

1. 丸塚浩助、浅田祐士郎：動脈硬化と血小板・凝固線溶系、別冊医学のあゆみ血液疾患 Ver.3、pp320-3 (2005)、坂田洋一、小澤敬也　編、医歯薬出版株式会社

2. 山下　篤、浅田祐士郎：血管と内皮の構造、図説　血栓・止血・血管学、pp22-6 (2005)、一瀬白帝　編著、中外医学社

■総説

1. 浅田祐士郎：Vascular Biologyからみた血栓・線溶系の基礎と臨床（座談会）、分子心血管病 2005; 6: 1-12.

2. 丸塚浩助、畠山金太、浅田祐士郎：病理学的見地からみた血栓・線溶系の役割、分子心血管病 2005; 6: 19-26.

3. 南野直人、浅田祐士郎：アドレノメデユリンの生体内分布と産生調節、ホルモンと臨床 2005; 53: 259-8.

4. 浅田祐士郎：病理からみた危険なプラーク、心臓病 2005; 37: 112-6.

5. 浅田祐士郎：動脈血栓形成における炎症免疫反応の関与、臨床血液 2005; 46: 83-90.

6. 山下　篤、浅田祐士郎：血小板とアテローム血栓（病理学的立場）、血栓と循環 2005; 13: 10-3.

7. Marutsuka K, Hatakeyama K, Yamashita A, Asada Y. Role of thrombogenic factors in the development of atherosclerosis. J Atheroscler Thromb. 2005; 12: 1-8.

8. 畠山金太、丸塚浩助、山下　篤、浅田祐士郎：プラークの破裂とびらんの病理、血管医学 2005; 6: 97-104.

9. 丸塚浩助、浅田祐士郎、住吉昭信：MODSと播種性血管内凝固症候群 (DIC)、病理と臨床 2005; 23: 1086-92.

10. 浅田祐士郎：心血管イベントの発症機序の解明、Vision 2005; 12: 22-4.

11. 丸塚浩助、浅田祐士郎：DICの病理所見、臨床医 2005; 31: 1694-6.

12. 畠山金太、丸塚浩助、山下　篤、浅田祐士郎、住吉昭信：心と脳の動脈硬化、成人病と生活習慣病 2005; 35: 1089-96.

13. 佐藤勇一郎、浅田祐士郎：血管炎症候群、血栓と循環 2005; 13: 390-4.

■症例報告

１、Yamashita A, Marutsuka K, Moriguchi S, Shimizu T, Matsuzaki Y, Onitsuka T, Asada Y. Neuroendocrine carcinoma of the posterior mediastinum arising from a foregut cyst. Pathol Int. 2005; 55: 285-9.

2. 三橋龍馬、公文崇詞、後藤英一、黒木浩史、久保紳一郎、帖佐悦男、小牧　亘、山下　篤、浅田祐士郎、桐谷　力、藤木　徹、木屋博昭：著明な硬膜外石灰沈着をきたした長期透析患者の１例、宮崎医学会誌 2005; 29: 56-60.

3. 佐藤信也、荒武八起、盛口清香、大野招伸、日野浦雄之、岡山昭彦、浅田祐士郎、丸塚浩助：捺印細胞診ギムザ染色において多数の細胞内顆粒を認め、神経内分泌分化を示した男性乳癌の１例、日臨細胞九州会誌 2005; 36: 23-8.