{"id":19,"date":"2017-07-15T21:15:09","date_gmt":"2017-07-15T12:15:09","guid":{"rendered":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/menekikansen\/?page_id=19"},"modified":"2021-12-10T16:16:23","modified_gmt":"2021-12-10T07:16:23","slug":"research","status":"publish","type":"page","link":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/menekikansen\/classroom\/research\/","title":{"rendered":"\u7814\u7a76\u7d39\u4ecb"},"content":{"rendered":"
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\u7814\u7a76\u7d39\u4ecb<\/h2>\n
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\u30ea\u30a6\u30de\u30c1\u6027\u75be\u60a3\u3068HTLV-1\u611f\u67d3\u75c7\uff08\u96e3\u75c5\u30d7\u30e9\u30c3\u30c8\u30db\u30fc\u30e0\uff09<\/h3>\n

HTLV-1\uff08\u30d2\u30c8T<\/span>\u7d30\u80de\u767d\u8840\u75c5\u30a6\u30a4\u30eb\u30b9\uff11\u578b\uff09\u306fATL\uff08<\/span>\u6210\u4ebaT<\/span>\u7d30\u80de\u767d\u8840\u75c5\uff09\u3084HAM\uff08HTLV-1<\/span>\u95a2\u9023\u810a\u9ac4\u708e\uff09\u306e\u539f\u56e0\u30a6\u30a4\u30eb\u30b9\u3067\u3059\u3002\u4e5d\u5dde\u30fb\u6c96\u7e04\u5730\u65b9\u306b\u611f\u67d3\u8005\u304c\u591a\u3044\u306e\u3067\u3059\u304c\u3001\u8fd1\u5e74\u3067\u306f\u5927\u90fd\u5e02\u570f\u3067\u3082\u611f\u67d3\u8005\u6570\u304c\u5897\u52a0\u50be\u5411\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u3001HTLV-1<\/span>\u611f\u67d3\u304c\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u708e\u75c7\u75c5\u614b\u3092\u5897\u60aa\u3055\u305b\u308b\u53ef\u80fd\u6027\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u6a5f\u5e8f\u306f\u4e0d\u660e\u3067\u3059\u3002HTLV-1<\/span>\u611f\u67d3\u3068\u708e\u75c7\u306e\u95a2\u9023\u3092\u660e\u3089\u304b\u306b\u3057\u3001\u591a\u304f\u306e\u60a3\u8005\u3055\u3093\u306b\u8ca2\u732e\u3059\u308b\u305f\u3081\u3001\u57fa\u790e\u7814\u7a76\u30fb\u81e8\u5e8a\u7814\u7a76\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n

\u57fa\u790e\u7814\u7a76\u3067\u306f2020<\/span>\u5e74\u306b\u300cHTLV-1<\/span>\u967d\u6027\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u708e\u75c7\u75c5\u614b\u306b\u304a\u3051\u308bIFN<\/span>\u30b7\u30b0\u30cd\u30c1\u30e3\u30fc\u306e\u89e3\u660e\u300d\u304c\u79d1\u7814\u8cbb\u306b\u63a1\u629e\u3055\u308c\u307e\u3057\u305f\u30022020<\/span>\u5e74\u304b\u3089\u306f\u3001AMED<\/span>\u304c\u63a8\u9032\u3059\u308b\u96e3\u75c5\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306b\u30012012<\/span>\u5e74\u304b\u3089\u904b\u55b6\u3057\u3066\u304d\u305fHTLV-1<\/span>\u967d\u6027\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u304c\u9023\u7d50\u3055\u308c\u3001\u5168\u56fd\u306e\u533b\u7642\u6a5f\u95a2\u3068\u9023\u643a\u3057\u305f\u4ed6\u65bd\u8a2d\u5171\u540c\u30ec\u30b8\u30b9\u30c8\u30ea\u7814\u7a76\u304c\u30b9\u30bf\u30fc\u30c8\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305fHTLV-1\u967d\u6027\u306e\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3067\u306f\u3001\u751f\u7269\u5b66\u7684\u88fd\u5264\u306a\u3069\u5c0e\u5165\u306e\u969b\u306b\u5b9f\u65bd\u3055\u308c\u308b\u6f5c\u5728\u6027\u7d50\u6838\u611f\u67d3\u75c7\uff08LTBI<\/span>\uff09\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\u306e\u5224\u5b9a\u4e0d\u80fd\u4f8b\u304c\u591a\u304f\u3001\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u3092\u8ad6\u6587\u3067\u767a\u8868\u3057\u3001\u9069\u5207\u306aLTBI<\/span>\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\u3064\u3044\u3066\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\u3000\u4e3b\u306a\u8ad6\u6587\uff1a<\/td>\nHashiba Y, et al. Mod Rheumatol. 2021 (in press)<\/span><\/td>\n<\/tr>\n
<\/td>\nUmekita K, et al. PLoS One. 2020;15 (5): e0233159.<\/td>\n<\/tr>\n
<\/td>\nUmekita K, et al. Front Microbiol. 2020; 11: 152.<\/td>\n<\/tr>\n
<\/td>\nIwao C, et al. Intern Med. 2020; 59(15): 1891-1897.<\/td>\n<\/tr>\n
<\/td>\nUmekita K, et al. Mod Rheumatol. 2019; 29(5): 795-801.<\/td>\n<\/tr>\n
<\/td>\nSuzuki T, et al. Arthritis Rheumatol. 2018; 70(7): 1014-1021.<\/td>\n<\/tr>\n
<\/td>\nTakajo I, et al. Intern Med. 2018; 57(14): 2071-2075.<\/td>\n<\/tr>\n
<\/td>\nHashiba Y, et al. Mod Rheumatol Case Rep. 2018; 2: 9-13.<\/td>\n<\/tr>\n
<\/td>\nUmekita K, et al. Mod Rheumatol. 2015; 25(5): 794-7.<\/td>\n<\/tr>\n
<\/td>\nUmekita K, et al. Arthritis Care Res (Hoboken). 2014; 66: 788-792.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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SFTS\u306e\u65e9\u671f\u8a3a\u65ad\u3068\u4e88\u5f8c\u6539\u5584\u306b\u8cc7\u3059\u308b\u7814\u7a76<\/h3>\n

SFTS(\u91cd\u75c7\u71b1\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u5019\u7fa4)\u306f\u3001\u30de\u30c0\u30cb\u306b\u3088\u3063\u3066SFTS\u30a6\u30a4\u30eb\u30b9\u304c\u5a92\u4ecb\u3055\u308c\u308b\u3053\u3068\u3067\u767a\u75c7\u3057\u3001\u81f4\u6b7b\u7387\u306e\u975e\u5e38\u306b\u9ad8\u3044\u75be\u60a3\u3067\u3059\u3002\u56fd\u5185\u3067\u306e\u60a3\u8005\u5831\u544a\u6570\u306f\u5bae\u5d0e\u770c\u304c\u6700\u591a\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002SFTS\u306e\u91cd\u75c7\u5316\u306e\u6a5f\u5e8f\u3082\u4e0d\u660e\u306a\u70b9\u304c\u591a\u304f\u3001\u75c5\u614b\u3092\u89e3\u660e\u3057\u9069\u5207\u304b\u3064\u8fc5\u901f\u306a\u8a3a\u65ad\u30fb\u6cbb\u7642\u306b\u3064\u306a\u3052\u308b\u3053\u3068\u304c\u6025\u52d9\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306b\u7c21\u6613\u8fc5\u901f\u8a3a\u65ad\u691c\u67fb\u6cd5\u306e\u958b\u767a\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u304c\u3001\u3088\u308a\u81e8\u5e8a\u73fe\u5834\u3067\u4f7f\u3044\u52dd\u624b\u306e\u826f\u3044\u691c\u67fb\u8a66\u85ac\u306e\u6539\u826f\u3092\u91cd\u306d\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u81e8\u5e8a\u7814\u7a76\u306b\u3082\u529b\u3092\u5165\u308c\u3066\u304a\u308a\u3001\u540c\u3058\u304f\u30de\u30c0\u30cb\u5a92\u4ecb\u611f\u67d3\u75c7\u3067\u3042\u308b\u65e5\u672c\u7d05\u6591\u71b1\u3068\u306e\u6bd4\u8f03\u3084\u6b7b\u4ea1\u4e88\u6e2c\u56e0\u5b50\u306e\u691c\u8a0e\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u6295\u4e0e\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u8ad6\u6587\u3067\u767a\u8868\u3057\u305f\u4ed6\u3001\u5bae\u5d0e\u770c\u5185\u3067\u306e\u30ec\u30b8\u30b9\u30c8\u30ea\u3082\u7acb\u3061\u4e0a\u3052\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n\n
\u3000\u4e3b\u306a\u8ad6\u6587\uff1a<\/td>\nKawaguchi T, et al. Viruses. 2021; 13(5): 78.<\/td>\n<\/tr>\n
<\/td>\nIwao K, et al. Viruses. 2021; 13(6): 1086.<\/td>\n<\/tr>\n
<\/td>\nKawaguchi T, et al. Open Forum Infect Dis. 2020; 7(11): ofaa473.<\/td>\n<\/tr>\n
<\/td>\nUmeki K, et al. J Virol Methods. 2020; 285: 113942.<\/td>\n<\/tr>\n
<\/td>\nKawaguchi T, et al. J Infect Chemother. 2016; 22(9): 633-7.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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HTLV-1\u7dcf\u5408\u5bfe\u7b56\u3078\u306e\u8ca2\u732e<\/h3>\n

AMED\u63a1\u629e\u8ab2\u984c\u3067\u3042\u308b\u300cHTLV-1\u967d\u6027\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u7dcf\u5408\u7684\u306a\u611f\u67d3\u5bfe\u7b56\u306b\u8cc7\u3059\u308b\u7814\u7a76\u300d\u3078\u53c2\u52a0\u3057\u3001HTLV-1\u611f\u67d3\u75c7\u306e\u8fc5\u901f\u8a3a\u65ad\u3084\u8a3a\u65ad\u6280\u8853\u306e\u958b\u767a\u306b\u5354\u529b\u3057\u3066\u3044\u307e\u3059\u3002\u4e16\u754c\u4e2d\u3067500-1000\u4e07\u4eba\u306e\u4eba\u3005\u304cHTLV-1\u306b\u611f\u67d3\u3057\u3066\u3044\u308b\u3068\u63a8\u5b9a\u3055\u308c\u3066\u304a\u308a\u3001WHO\u304c\u8fd1\u5e74\u65e9\u671f\u8a3a\u65ad\u3084\u611f\u67d3\u4e88\u9632\u306b\u529b\u3092\u5165\u308c\u3066\u3044\u308b\u5206\u91ce\u3067\u3042\u308a\u91cd\u8981\u306a\u8ab2\u984c\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n
\u3000\u4e3b\u306a\u8ad6\u6587\uff1a<\/td>\nUmeki K, et al. Clin Lab. 2017; 63(2): 227-233.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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\u95a2\u9023\u5b66\u4f1a<\/h4>\n