{"id":136,"date":"2014-11-15T10:55:10","date_gmt":"2014-11-15T01:55:10","guid":{"rendered":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english-proto\/?p=136"},"modified":"2016-06-01T11:05:21","modified_gmt":"2016-06-01T02:05:21","slug":"physics","status":"publish","type":"post","link":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/laboratories\/physics\/","title":{"rendered":"Chemistry"},"content":{"rendered":"

Combing chemistry and biology, the long-term objective of our research is to investigate DNA and RNA conformational changes associated with biological events for further understanding the life phenomenon and benefit to human.<\/p>\n

Project<\/h3>\n
    \n
  1. Understanding the structures and function of human telomere DNA and RNA by chemical approaches<\/li>\n
  2. Developing various chemical methods to targeting human telomeres and telomerase for the treatment of cancer\"\"<\/a><\/li>\n<\/ol>\n

    Lab technique<\/h3>\n
    Chemistry<\/span>
    \n<\/strong><\/strong><\/p>\n
      \n
    • Synthesis: artificial nucleic acid or functional molecule<\/li>\n<\/ul>\n<\/div>\n
      Biotechnology<\/strong><\/span><\/div>\n
      \n
        \n
      • Gel electrophoresis<\/li>\n
      • Polymerase chain reaction (PCR)<\/li>\n
      • DNA array<\/li>\n
      • Molecular Cloning<\/li>\n
      • DNA sequencing<\/li>\n
      • Southern, Northern, Western blotting<\/li>\n<\/ul>\n<\/div>\n

        Publication<\/h3>\n
          \n
        1. Sci. Rep.<\/strong>\u00a05, 13693, 2015.<\/strong><\/em><\/li>\n
        2. Bioorg. Med. Chem.<\/strong>\u00a022, 4419, 2014.<\/strong><\/em><\/li>\n
        3. J. Am. Chem. Soc.<\/strong>\u00a0135, 14,\u00a02013.<\/strong><\/em><\/li>\n
        4. J. Am. Chem. Soc.<\/strong>\u00a0135, 18786, 2013.<\/strong><\/em><\/li>\n
        5. Angew. Chem. Int. Ed.<\/strong>\u00a052, 13681, 2013.<\/strong><\/em><\/li>\n
        6. J. Biol. Chem.<\/strong>\u00a0287, \u00a041787, 2012.<\/strong><\/em><\/li>\n
        7. Angew. Chem. Int. Ed.<\/strong>\u00a051, 13681, 2012.<\/strong><\/em><\/li>\n
        8. Nature Communications,<\/strong>\u00a02(1), 2011.<\/strong><\/em><\/li>\n
        9. J. Am. Chem. Soc.<\/strong>\u00a0133, 19153, 2011.<\/strong><\/em><\/li>\n
        10. Proc. Natl. Acad. Sci. USA. <\/strong>107, 14579, 2010.<\/strong><\/em><\/li>\n
        11. Nature Protocols<\/strong> 2, 78, 2007.<\/strong><\/em><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

          Combing chemistry and biology, the long-term objective of our research is to investigate DNA and RNA conformat […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false},"categories":[1],"tags":[],"_links":{"self":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/posts\/136"}],"collection":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/comments?post=136"}],"version-history":[{"count":14,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/posts\/136\/revisions"}],"predecessor-version":[{"id":138,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/posts\/136\/revisions\/138"}],"wp:attachment":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/media?parent=136"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/categories?post=136"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/english\/wp-json\/wp\/v2\/tags?post=136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}