{"id":50,"date":"2014-05-14T20:10:55","date_gmt":"2014-05-14T11:10:55","guid":{"rendered":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/?page_id=50"},"modified":"2026-03-04T13:23:51","modified_gmt":"2026-03-04T04:23:51","slug":"publication-4","status":"publish","type":"page","link":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/publication-4\/","title":{"rendered":"\u696d\u7e3e"},"content":{"rendered":"

2026<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Fidya, Ishizuka T, Kubota T, Kai K, Hishikawa Y.\u00a0The Crucial Role of GPR30 and Histone Crotonylation during the Inflammatory Repair Process in Ligature-Induced Periodontitis. Acta Histochem. Cytochem. <\/strong>2026, in press<\/em>.<\/p>\n

Kubota T, Kaneuji T, Ishizuka T, Kai K, Yamashita Y, Hishikawa Y. Extracellular volume fraction and tumor fibrosis as non-invasive prognostic biomarkers in tongue squamous cell carcinoma. International Journal of Oral & Maxillofacial Surgery<\/strong> 2026, in press<\/em>.<\/p>\n

\u3010\u539f\u8457\u3011\uff08\u548c\u6587\uff09<\/strong><\/p>\n

\u7af9\u5165 \u6075\u7f8e\uff0c\u7be0\u7530 \u88d5\u7f8e\uff0c\u7532\u6590 \u5065\u543e\uff0c\u6ff5\u7530 \u525b\u81e3\uff0c\u7af9\u751f\u307e\u3086\u307f\uff0c\u5150\u7389 \u88d5\u5b50\uff0c\u6728\u4e0b\u7531\u7f8e\u5b50. \u770b\u8b77\u5b66\u751f\u3078\u306e\u30b9\u30c8\u30fc\u30de\u30b1\u30a2\u6559\u80b2\u306b\u304a\u3051\u308b\u30aa\u30b9\u30c8\u30e1\u30a4\u30c8\u7591\u4f3c\u4f53\u9a13VR\u6620\u50cf\u306e\u6d3b\u7528\uff5e\u5b66\u751f\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8cea\u554f\u7d19\u8abf\u67fb\uff5e. \u65e5\u672c\u30b9\u30c8\u30fc\u30de\uff65\u6392\u6cc4\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u5b66\u4f1a\u8a8c<\/strong>\u00a02026, in press<\/em>.<\/p>\n

2025<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Kai K, Ishizuka T, Matsumoto J, Shimamawari K, Mori R, Fidya, Lkham-Erdene B, Kubota T, Ikenoue M, Higuchi K, Nanashima A, Hishikawa Y. Non-Cytotoxic Photodynamic Therapy with Talaporfin Sodium Reduces the Expression of CXCR4 and Enhances Chemotherapeutic Efficacy in Undifferentiated Gastric Cancer Cell Line HGC27.\u00a0Acta Histochem. Cytochem.<\/strong> 2025, 58(2):69-79. doi: 10.1267\/ahc.25-00002.<\/p>\n

Higuchi K, Ikenoue M, Ishizuka T, Kai K, Takahashi N, Kubota T, Shirouzu S, Lkham-Erdene B,\u00a0 <\/span>Mo Aung K, Nakai M, Sawaguchi A, Nanashima A, Hishikawa Y. SETDB1-mediated chromatin regulation in intestinal epithelial cells during intestinal ischemia-reperfusion injury. Acta Histochem. Cytochem. <\/strong>2025, 58 (1): 9-18. doi: 10.1267\/ahc.24-00061.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd \u5584\u9686, \u77f3\u585a \u5320, <\/span>\u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66. In situ<\/em> hybridization\u6cd5. \u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong>. 87-97, 2025. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237<\/p>\n

\u3010\u8cde<\/span><\/span>\u3011<\/strong><\/p>\n

2025\u5e74\u5ea6 \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a Paul K. Nakane AHC Award (Gold medal)<\/strong><\/p>\n

Choijookhuu N, Shibata Y, Ishizuka T, Xu Y, Koji T, Hishikawa Y. An advanced detection system for in situ<\/em> hybridization using a fluorescence resonance energy transfer\u2013based molecular beacon probe. Acta Histochem. Cytochem.<\/strong> 2022, 55, 119-128. doi: 10.1267\/ahc.22-00075.<\/p>\n

2025\u5e74\u5ea6 \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a Paul K. Nakane AHC Award (Silver medal)<\/strong><\/p>\n

Murakami M, Kawakami R, Niko Y, Tsuda T, Mori H, Yatsuzuka K, Imamura T, Sayama K. High-quality Fluorescence Imaging of the Human Acrosyringium Using a Transparency: Enhancing Technique and an Improved, Fluorescent Solvatochromic Pyrene Probe. Acta Histochem. Cytochem.<\/strong> 2020, 53, 131-138. doi: 10.1267\/ahc.20-00020.<\/p>\n

2025\u5e74\u5ea6\uff08\u7b2c27\u56de\uff09\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\u8ad6\u6587\u8cde\u3000<\/strong><\/p>\n

Lkham-Erdene B, Choijookhuu N, Kubota T, Uto T, Mitoma S, Shirouzu S, Ishizuka T, Kai K, Higuchi K, Mo Aung K, Batmunkh JE, Sato K, Hishikawa Y.\u00a0 Effect of hepatic lipid overload on accelerated hepatocyte proliferation promoted by HGF expression via the SphK1\/S1PR2 pathway in MCD\u2013diet mouse partial hepatectomy. Acta Histochem. Cytochem.<\/strong> 2024, 57(5): 175-188. doi: 10.1267\/ahc.24-00046.<\/p>\n

2025\u5e74\u5ea6\uff08\u7b2c22\u56de\uff09\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a \u82e5\u624b\u7814\u7a76\u8005\u5b66\u8853\u5968\u52b1\u8cde\u3000<\/strong>\u6a0b\u53e3 \u548c\u5b8f<\/p>\n

\u65e5\u672c\u89e3\u5256\u5b66\u4f1a\u7b2c81\u56de\u4e5d\u5dde\u652f\u90e8\u5b66\u8853\u96c6\u4f1a \u512a\u79c0\u8cde\u3000<\/strong>\u4e45\u4fdd\u7530 \u58fd\u6a39<\/p>\n

\u7b2c70\u56de\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a \u512a\u79c0\u30dd\u30b9\u30bf\u30fc\u8cde\u3000<\/strong>\u4e45\u4fdd\u7530 \u58fd\u6a39<\/p>\n

2024<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Lkham-Erdene B, Choijookhuu N, Kubota T, Uto T, Mitoma S, Shirouzu S, Ishizuka T, Kai K, Higuchi K, Mo Aung K, Batmunkh JE, Sato K, Hishikawa Y.\u00a0 Effect of hepatic lipid overload on accelerated hepatocyte proliferation promoted by HGF expression via the SphK1\/S1PR2 pathway in MCD\u2013diet mouse partial hepatectomy. Acta Histochem. Cytochem.<\/strong> 2024, 57(5): 175-188. doi: 10.1267\/ahc.24-00046.<\/p>\n

Kai K, Shinoda H, Takeiri E, Hamada T, Chikubu M, Kodama Y, Higuchi K, Nanashima A. Acceptance of Virtual Reality Simulation Training for Stoma Care by Healthcare Providers: A Pilot Questionnaire Study After Viewing Prototype Imagings. Cureus<\/strong> 2024 Jul 26;16(7):e65465. doi: 10.7759\/cureus.65465.<\/p>\n

Choijookhuu N, Yano K, Lkham-Erdene B, Shirouzu S, Kubota T, Fidya, Ishizuka T, Kai K, Chosa E, Hishikawa Y. HMGB2 Promotes De Novo Lipogenesis to Accelerate Hepatocyte Proliferation During Liver Regeneration. J. Histochem. Cytochem.<\/strong> 2024 Apr;72(4):245-264. doi: 10.1369\/00221554241241569.<\/p>\n

Ikenoue M, Choijookhuu N, Yano K, Fidya, Takahashi N, Ishizuka T, Shirouzu S, Yamaguma Y, Kai K, Higuchi K, Sawaguchi A, Nanashima A, Hishikawa Y. The crucial role of SETDB1 in structural and functional transformation of epithelial cells during regeneration after intestinal ischemia reperfusion injury. Histochem. Cell Biol.<\/strong> 2024 Apr;161(4):325-336. doi: 10.1007\/s00418-023-02263-9.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Kai K, Nakashima K, Kawakami H, Takeno S, Hishikawa Y, Ikenoue M, Hamada T, Imamura N, Shibata T, Noritomi T, Sasaki F, Nakamura Y, Nanashima A. Clinical Impact of the Charlson Comorbidity Index on the Efficacy of Salvage Photodynamic Therapy Using Talaporfin Sodium for Esophageal Cancer. Intern Med. <\/strong>2024 Apr 1;63(7):903-910. <\/span>\u00a0doi: 10.2169\/internalmedicine.1907-23.<\/span><\/p>\n

Fidya, Choijookhuu N, Ikenoue M, Yano K, Yamaguma Y, Shirouzu S, Kai K, Ishizuka T, Hishikawa Y. Protective role of estrogen through G-protein coupled receptor 30 in a colitis mouse model. Histochem Cell Biol.<\/strong> 2024 Jan;161(1):81-93. doi: 10.1007\/s00418-023-02235-z.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd \u5584\u9686, \u77f3\u585a \u5320, <\/span>\u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66. In situ<\/em> hybridization\u6cd5. \u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong>. 45-53, 2024. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237<\/p>\n

2023<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Nagai T, Sekimoto T, Kurogi S, Ohta T, Miyazaki S, Yamaguchi Y, Tajima T, Chosa E, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Sato K, Hishikawa Y, Funamoto T. Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway. Sci Rep.<\/strong> 2023 Sep 5;13(1):14639. doi: 10.1038\/s41598-023-41837-4.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Uto T, Fukaya T, Mitoma S, Nishikawa Y, Tominaga M, Choijookhuu N, Hishikawa Y, Sato K. Clec4A4 Acts as a Negative Immune Checkpoint Regulator to Suppress Antitumor Immunity. Cancer Immunol Res.<\/strong> 2023 Sep 1;11(9):1266-1279. doi: 10.1158\/2326-6066.CIR-22-0536.<\/p>\n

Nakamura T, Sakaguchi H, Mohri H, Ninoyu Y, Goto A, Yamaguchi T, Hishikawa Y, Matsuda M, Saito N, Ueyama T. Dispensable role of Rac1 and Rac3 after cochlear hair cell specification. J Mol Med.<\/strong> 2023 Jul;101(7):843-854. doi: 10.1007\/s00109-023-02317-4.<\/p>\n

Fukaya T, Uto T, Mitoma S, Takagi H, Nishikawa Y, Tominaga M, Choijookhuu N, Hishikawa Y, Sato K. Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells. Cell Rep.<\/strong> 2023 May 30;42(5):112431. doi: 10.1016\/j.celrep.2023.112431.<\/p>\n

Kai K, Hiyoshi M, Imamura N, Hamada T, Yano K, Sato Y, Sakae T, Komi M, Nakamura T, Choijookhuu N, Hishikawa Y, Nanashima A. A Preliminary Pathological Evaluation of Extracellular Volume Fraction with Contrast-enhanced Computed Tomography as a Novel Quantitative Parameter of Pancreatic Fibrosis. Intern Med.<\/strong> 2023;62(8):1107-1115. doi: 10.2169\/internalmedicine.0410-22.<\/p>\n

Kai K, Hamada T, Sato Y, Hiyoshi M, Imamura N, Yano K, Ikeda T, Ichihara A, Ogata S, Choijookhuu N, Hishikawa Y, Hosokawa A, Nanashima A. Extracellular Volume Fraction Calculated Using Contrast-Enhanced Computed Tomography as a Biomarker of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome: A Preliminary Histopathological Analysis. J Oncol.<\/strong> 2023 Feb 14;2023:1440257. doi: 10.1155\/2023\/1440257.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u7dcf\u8aac\u3011<\/strong><\/p>\n

\u77f3\u585a <\/span>\u5320, <\/span>Narantsog Choijookhuu, \u67f4\u7530 <\/span>\u606d\u660e, \u5c0f\u8def <\/span>\u6b66\u5f66, \u83f1\u5ddd <\/span>\u5584\u9686. <\/span>\u86cd\u5149\u5171\u9cf4\u30a8\u30cd\u30eb\u30ae\u30fc\u79fb\u52d5<\/span>(FRET)\u73fe\u8c61\u3092\u5229\u7528\u3057\u305f<\/span> \u9ad8\u611f\u5ea6<\/span> in situ<\/em> hybridization. \u9855\u5fae\u93e1<\/strong> 2023, 58(3), 117-122.<\/p>\n

\u83f1\u5ddd \u5584\u9686, Narantsog Choijookhuu, \u77f3\u585a \u5320, <\/span>\u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66. In situ<\/em> hybridization\u6cd5. \u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong>. 177-187, 2023. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237<\/p>\n

\u3010\u8cde<\/span><\/span>\u3011<\/strong><\/p>\n

2023\u5e74\u5ea6\uff08\u7b2c25\u56de\uff09\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\u8ad6\u6587\u8cde\u3000<\/strong><\/p>\n

Choijookhuu N, Shibata Y, Ishizuka T, Xu Y, Koji T, Hishikawa Y. An advanced detection system for in situ<\/em> hybridization using a fluorescence resonance energy transfer\u2013based molecular beacon probe. Acta Histochem. Cytochem.<\/strong> 2022, 55, 119-128. doi: 10.1267\/ahc.22-00075.<\/p>\n

2022<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Shirouzu S, Sugita N, Choijookhuu N, Yamaguma Y, Takeguchi K, Ishizuka T, Tanaka M, Fidya, Kai K, Chosa E, Yamashita Y, Koshimoto C and Hishikawa Y. Pivotal role of High-Mobility Group Box 2 in ovarian folliculogenesis and fertility. J Ovarian Res.<\/strong> 2022, 15, 133. doi: 10.1186\/s13048-022-01071-4.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

He Z, Ishizuka T, Hishikawa Y, Xu Y. Click chemistry for fluorescence imaging via combination of a BODIPY-based \u2018turn-on\u2019 probe and a norbornene glucosamine. Chem. Commun.<\/strong> 2022, 58, 12479-12482. doi:10.1039\/D2CC05359D.<\/p>\n

Choijookhuu N, Shibata Y, Ishizuka T, Xu Y, Koji T, Hishikawa Y. An advanced detection system for in situ<\/em> hybridization using a fluorescence resonance energy transfer\u2013based molecular beacon probe. Acta Histochem. Cytochem.<\/strong> 2022, 55, 119-128. doi: 10.1267\/ahc.22-00075.<\/p>\n

Yano K, Choijookhuu N, Ikenoue M, Fidya, Fukaya T, Sato K, Lee D, Taniguchi N, Chosa E, Nanashima A, Hishikawa Y. Spatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration. Sci. Rep.<\/strong> 2022 12:11962. doi: 10.1038\/s41598-022-16258-4.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span>
\n<\/strong><\/p>\n

Miyazaki S, Funamoto T, Sekimoto T, Kurogi S, Ohta T, Nagai T, Tajima T, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Hishikawa Y, Chosa E. EPLIN\u03b2 Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation. Acta Histochem. Cytochem.<\/strong> 2022 55(3):99-110. doi: 10.1267\/ahc.22-00027.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Yamaguma Y, Sugita N, Choijookhuu N, Yano K, Lee D, Ikenoue M, Fidya, Shirouzu S, Ishizuka T, Tanaka M, Yamashita Y, Chosa E, Taniguchi N, Hishikawa Y.\u00a0 Crucial role of high-mobility group box 2 in mouse ovarian follicular development through estrogen receptor beta. Histochem. Cell Biol<\/strong>. 2022 157:359\u2013369 doi: 10.1007\/s00418-022-02074-4.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span>
\n<\/span><\/p>\n

Hishikawa Y, Takizawa T, Koji T. In focus in HCB: new histochemical insights into mammalian gametogenesis. Histochem. Cell Biol.<\/strong> 2022 157(3):269-271. doi: 10.1007\/s00418-022-02083-3.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686, Narantsog Choijookhuu, \u77f3\u585a\u5320, \u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66.: \u304c\u3093\u306e\u5206\u5b50\u75c5\u7406\u5b66\uff08\u5e8f\u8ad6\uff09\u89e3\u6790\u6cd5 1.FISH\u30fbISH.<\/strong><\/em> \u75c5\u7406\u3068\u81e8\u5e8a\u3010\u81e8\u6642\u5897\u520a\u53f7\u3011\u30fb\u5225\u5237 2022 vol.40.<\/strong><\/em> 41-46, \u6771\u4eac\uff0f\u6587\u5149\u5802\uff0f\u672c\u90f7<\/p>\n

\u83f1\u5ddd \u5584\u9686, Narantsog Choijookhuu, \u77f3\u585a \u5320, <\/span>\u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66. In situ<\/em> hybridization\u6cd5. \u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong>. 111-120, 2022. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237<\/p>\n

2021<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Sugita N, Choijookhuu N, Yano K, Lee D, Ikenoue M, Fidya, Taniguchi N, Chosa E, Hishikawa Y. Depletion of HMGB2 causes seminiferous tubule atrophy via aberrant expression of androgen and estrogen receptors in mouse testis. Biol. Reprod.<\/strong>\u00a02021 105:1510-1520. <\/span> doi: 10.1093\/biolre\/ioab187<\/span>.\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/span><\/p>\n

Nishikawa Y, Fukaya T, Fukui T, Uto T, Takagi H, Nasu J, Miyanaga N, Riethmacher D, Choijookhuu N, Hishikawa Y, Amano M, Sato K.<\/span>\u00a0Congenital Deficiency of Conventional Dendritic Cells Promotes the Development of Atopic Dermatitis-Like Inflammation. Front Immunol.<\/strong> 2021 Jul 27;12:712676. doi: 10.3389\/fimmu.2021.712676. eCollection 2021.<\/span><\/p>\n

Sawaguchi A, Kamimura T, Takahashi N, Yamashita A, Asada Y, Imazato H, Aoyama F, Wakui A, Sato T, Choijookhuu N, Hishikawa Y. <\/span>In situ<\/em> strategy for biomedical target localization via nanogold nucleation and secondary growth. Commun. Biol<\/strong>. 2021 4:710. doi: 10.1038\/s42003-021-02246-3.<\/span><\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686, \u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66.: in situ<\/em> hybridization\u6cd5\u306e\u539f\u7406\u3068\u5fdc\u7528. \u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong> 2021. 107-120, 2021. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237<\/p>\n

2020<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Miyanaga N, Takagi H, Uto T, Fukaya T, Nasu J, Fukui T, Nishikawa Y, Sparwasser T, Choijookhuu N, Hishikawa Y, Nakamura T, Tono T, and Sato K.: Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy. Commun. Biol.<\/strong> 2020 3(1):742. doi: 10.1038\/s42003-020-01466-3.<\/p>\n

Mai NNH, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, Sato K, Tuan LQ, Hishikawa Y.: Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax\/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells. Acta Histochem. Cytochem<\/strong>.<\/em> 2020, 53 (4) 61-72 DOI: 10.1267\/ahc.20-00002 \u3010\u5b66\u4f4d\u8ad6\u6587\u3011
\n<\/span><\/p>\n

Fukui T, Fukaya T, Uto T, Takagi H, Nasu J,\u00a0Miyanaga N,\u00a0Nishikawa Y,\u00a0Koseki H,\u00a0Choijookhuu N, Hishikawa Y, Yamashita Y, Sato K.: Pivotal Role of CD103 in the Development of Psoriasiform Dermatitis. Sci. Rep<\/strong>.<\/em> 2020 May 20;10(1):8371. doi: 10.1038\/s41598-020-65355-9<\/p>\n

Diep NV, Choijookhuu N, Fuke N, Myint O, Izzati UZ, Suwanruengsri M, Hishikawa Y, Yamaguchi R.:\u00a0New Tropisms of Porcine Epidemic Diarrhoea Virus (PEDV) in Pigs Naturally Coinfected by Variants Bearing Large Deletions in the Spike (S) Protein and PEDVs Possessing an Intact S Protein.\u00a0Transbound. Emerg. Dis<\/strong>.<\/em> 2020 May DOI: 10.1111\/tbed.13607\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686, \u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66.: in situ<\/em> hybridization\u6cd5\u306e\u539f\u7406\u3068\u5fdc\u7528.<\/strong><\/em> \u7d44\u7e54\u7d30\u80de\u5316\u5b66 2020. <\/strong><\/em>107-121, 2020. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237<\/p>\n

\u3010\u8cde<\/span><\/span>\u3011<\/strong><\/p>\n

2020\u5e74\u5ea6\uff08\u7b2c22\u56de\uff09\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\u8ad6\u6587\u8cde\u3000<\/strong><\/p>\n

Kyaw MTH, Yamaguchi Y, Choijookhuu N, Yano K, Takagi H, Takahashi N, Oo PS, Sato K, Hishikawa Y.: The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells. Acta Histochem. Cytochem.<\/strong> 2019, 52:1-8<\/p>\n

2020\u5e74\u5ea6\uff08\u7b2c22\u56de\uff09\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\u8ad6\u6587\u8cde\u3000<\/strong><\/p>\n

Oo PS, Yamaguchi Y, Sawaguchi A, Kyaw MTH, Choijookhuu N, <\/strong>Ali MN, Srisowanna N, Hino SI, Hishikawa Y.: Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells. Acta Histochem. Cytochem<\/strong>. 2018, 51:21-31<\/p>\n

2019<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W.:\u00a0Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a.\u00a0Scientific Reports<\/strong><\/em> 2019, doi.org\/10.1038\/s41598-019-54544-w<\/p>\n

Phyu KP, Zin PW, Aung MN, Lar MM, Hishikawa Y, Maruyama M, Yokota H, Thant KZ, Wai KT, Yano Y.: Contamination of arsenic in drinking water in Ayeyarwady delta region, Myanmar. World Journal of Pharmaceutical and Life Sciences<\/strong>. 2019, 5(8):42-48<\/p>\n

Srisowanna N, Choijookhuu N, Yano K, Batmunkh B, Ikenoue M, Mai NNH, Yamaguchi Y and Hishikawa Y.: The effect of estrogen on hepatic fat accumulation during early phase of liver regeneration after partial hepatectomy in rats. Acta Histochem. Cytochem<\/strong>. 2019, 52 (4)1-9\u00a0doi.org\/10.1267\/ahc.19018\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Mochizuki H, Phyu KP, Aung MN, Zin PW, Yano Y, Myint MZ, Thit WM, Yamamoto Y, Hishikawa Y, Thant KZ, Maruyama M, Kuroda Y.: Peripheral neuropathy induced by drinking water contaminated with low-dose arsenic in Myanmar. Environ Health Prev Med.<\/strong> 2019 Apr 23;24(1):23. doi: 10.1186\/s12199-019-0781-0.<\/p>\n

Kyaw MTH, Yamaguchi Y, Choijookhuu N, Yano K, Takagi H, Takahashi N, Oo PS, Sato K, Hishikawa Y.: The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells. Acta Histochem. Cytochem.<\/strong> 2019, 52:1-8 \u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686, \u67f4\u7530\u606d\u660e, \u5c0f\u8def\u6b66\u5f66.: in situ<\/em> hybridization\u306e\u6700\u524d\u7dda \uff0d\u6280\u8853\u306e\u6700\u524d\u7dda\u306e\u72b6\u6cc1\u3068\u7814\u7a76\u30fb\u8a3a\u65ad\u3078\u306e\u5fdc\u7528\uff0d. \u75c5\u7406\u3068\u81e8\u5e8a<\/strong>Vol. 37, No.11: 1139-1144,\u6587\u5149\u5802, 2019<\/p>\n

\u83f1\u5ddd\u5584\u9686\uff1aIn situ<\/em> hybridization (RNA) \u306e\u57fa\u790e\u3068\u5fdc\u7528<\/span><\/span>\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b66 2019.<\/strong><\/em> 83-99, 2019. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u5b66\u969b\u4f01\u753b\uff0e<\/p>\n

2018<\/span><\/strong><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Fukaya T, Fukui T, Uto T, Takagi H, Nasu J, Miyanaga N, Arimura K, Nakamura T, Koseki H, Choijookhuu N, Hishikawa Y<\/strong>, Yamashita Y, Sato K.: Pivotal role of IL-22BP in the epithelial autoregulation of IL-22 signaling in the control of skin inflammation. Frontiers. Immunol<\/strong>. 2018 Jun 21;9:1418. doi: 10.3389\/fimmu.2018.01418. eCollection 2018<\/p>\n

Lee D, Taniguchi N, Sato K, Choijookhuu N, Hishikawa Y<\/strong>, Kataoka H, Morinaga H, Lotz M Chosa E.: HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles. Sci. Rep<\/strong>. 2018, doi:10.1038\/s41598-018-28023 \u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Ali MN, Choijookhuu N,<\/strong> Takagi H, Srisowanna N, Huynh MNH, Yamaguchi Y, Oo PS, Kyaw MTH, Sato K, Yamaguchi R,\u00a0 Hishikawa Y.:<\/strong> The HDAC Inhibitor, SAHA, Prevents Colonic Inflammation by Suppressing Pro-inflammatory Cytokines and Chemokines in DSS-induced Colitis. Acta Histochem. Cytochem<\/strong>. 2018, 51:33-40\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Oo PS, Yamaguchi Y, Sawaguchi A, Kyaw MTH, Choijookhuu N, <\/strong>Ali MN, Srisowanna N, Hino SI, Hishikawa Y.: Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells. Acta Histochem. Cytochem<\/strong>.2018, 51:21-31\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Uto T, Takagi H, Fukaya T, Nasu J, Fukui T, Miyanaga N, Arimura K, Nakamura T, Choijookhuu N<\/strong>, Hishikawa Y, Katsuaki Sato.: Critical role of plasmacytoid dendritic cells in induction of oral tolerance.\u00a0Journal of Allergy and Clinical Immunology. <\/strong>2018 141:2156-2167<\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686\uff1aIn situ<\/em> hybridization \u306e\u539f\u7406\u3068\u57fa\u790e\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b66 2018.<\/strong><\/em>\u00a0135-146, 2018. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237\uff0e<\/p>\n

2017 <\/span><\/strong><\/h2>\n

\u3010\u539f\u8457\u3011<\/strong><\/p>\n

Matsumoto J, Suzuki K, Yasuda M, Yamaguchi Y, Hishikawa Y, Imamura N, Nanashima A.: Photodynamic therapy of human biliary cancer cell line using combination of phosporus porphyrins and light emitting diode. Bioorg. Med. Chem.<\/strong> 2017, 25:6536-6541<\/p>\n

Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N.: Novel role of Rac-Mid1 signaling in medial cerebellar development. Development<\/span>.<\/strong> 2017, 144:1863-1875<\/p>\n

Honda A, Choijookhuu N, Izu H, Kawano Y, Inokuchi M, Honsho K, Lee AR, Nabekura H, Ohta H, Tsukiyama T, Ohinata Y, Kuroiwa A, Hishikawa Y, Saitou M, Jogahara T, Koshimoto C.: Flexible adaptation of male germ cells from female iPSCs of endangered Tokudaia osimensis<\/i>. Sci Adv<\/span>.<\/strong> 2017 May 12;3(5):e1602179. doi: 10.1126\/sciadv.1602179<\/p>\n

Honda A, Kawano Y, Izu H, Choijookhuu N, Honsho K, Nakamura T, Yabuta Y, Yamamoto T, Takashima Y, Hirose M, Sankai T, Hishikawa Y, Ogura A, Saitou M.: Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Na\u00efve Conversion. Sci Rep<\/span>.<\/strong> Mar 28;7:45285. 2017 doi: 10.1038\/srep45285<\/p>\n

Batmunkh B, Choijookhuu N, Srisowanna N, Byambatsogt U, Oo PS, Ali MN, Yamaguchi Y, Hishikawa Y.: Estrogen accelerates cell proliferation through estrogen receptor alpha during rat liver regeneration after partial hepatectomy. Acta Histochem. Cytochem.<\/strong> 2017, 50:39-48 \u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Tsuchiya K, Ikeda T, Batmunkh B, Choijookhuu N, Ishizaki H, Hotokezaka M, Hishikawa Y Nanashima A.: Frequency of CD4+CD161+ T cell and interleukin-10 expression in inflammatory bowel diseases. Acta Histochem. Cytochem.<\/strong> 2017, 50:21-28 \u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686\uff1aIn situ<\/em> hybridization \u6cd5\u30fc\u57fa\u790e\u7de8\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b66 2017.<\/strong><\/em>\u00a0159-169, 2017. \u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a(\u7de8), \u4e2d\u897f\u5370\u5237\uff0e<\/p>\n

2016 <\/strong><\/strong><\/span><\/h2>\n

\u3010<\/strong>\u539f\u8457\u3011<\/strong><\/strong><\/p>\n

Chayapong J, Madhyastha H, Madhyastha R, Nurrahmah QI, Nakajima Y, Choijookhuu N, Hishikawa Y, Maruyama M.: Arsenic trioxide induces ROS activity and DNA damage, leading to G0\/G1 extension in skin fibroblasts through the ATM-ATR-associated Chk pathway. Environ Sci Pollut Res<\/strong><\/em> Int. 2016 Dec 24. DOI 10.1007\/s11356-016-8215-7\u00a0 \u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Arimura K, Takagi H, Uto T, Fukaya T, Nakamura T, Choijookhuu N, Hishikawa Y, Yamashita Y, Sato K.: Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation. Mucosal Immunol<\/em><\/strong>. 2016, 10:957-970.\u00a0\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

Takagi H, Arimura K, Uto T, Fukaya T, Nakamura T, Choijookhuu N, Hishikawa Y, Sato K.: Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation. Sci Rep<\/strong><\/em>. 2016; 6: 24477. doi: 10.1038\/srep24477<\/p>\n

Yamaguchi Y, Madhyastha H, Madhyastha R, Choijookhuu N, Hishikawa Y, Pengjam Y, Nakajima Y, Maruyama M.: Arsenic acid inhibits proliferation of skin fibroblasts, and increases cellular senescence through ROS mediated MST1-FOXO signaling pathway. J Toxicol Sci<\/em><\/strong>.\u00a02016;\u00a041: 105-113.\u00a0\u3010\u5b66\u4f4d\u8ad6\u6587\u3011<\/span><\/p>\n

\u3010\u7dcf\u8aac\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686\uff1a\u907a\u4f1d\u5b50\u306e\u5c40\u5728\u3092\u898b\u308b\u2015 in situ<\/em> hybridization. Clinical Neuroscience<\/strong><\/em>. 2016 Vol. 34, No.6<\/p>\n

Choijookhuu N, Hino SI, Oo PS, Batmunkh B, Hishikawa Y.: The role of estrogen receptors in intestinal homeostasis and disease. Receptors Clin Investig<\/strong><\/em>. 2016 Vol 3, No 1; doi: 10.14800\/rci.1109<\/p>\n

2015<\/strong><\/strong><\/span><\/h2>\n

\u3010\u8457\u66f8\u3011<\/strong><\/p>\n

\u83f1\u5ddd\u5584\u9686\uff1aIn situ<\/em> hybridization \u6cd5\u306e\u539f\u7406\u3068\u57fa\u790e\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong><\/em> 2015.<\/strong> 77-91, 2015.\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\uff08\u7de8\uff09\uff0c\u4e2d\u897f\u5370\u5237\uff0e<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/strong><\/p>\n

Hino SI, Choijookhuu N, Hishikawa Y. \u5f62\u614b\u79d1\u5b66\u3092\u57fa\u76e4\u3068\u3057\u305f\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\u6cd5-in situ<\/em> hybridization\u6cd5\u3092\u4e2d\u5fc3\u306b. \u9855\u5fae\u93e1Vol. 50, No. 1, 2015<\/p>\n


\n\u3010<\/strong>\u539f\u8457\u3011<\/strong><\/p>\n

Muraoka I, Takatsuki M, Sakai Y, Tomonaga T, Soyama A, Hidaka M, Hishikawa Y, Koji T, Utoh R, Ohashi K, Okano T, Kanematsu T, Eguchi S.: Transplanted fibroblast cell sheets promote migration of hepatic progenitor cells in the incised host liver in allogenic rat model. J Tissue Eng Regen Med. 11:E108-115,\u00a02015.<\/p>\n

Choijookhuu N, Hino SI, Oo PS, Batmunkh B, Ali MN, Kyaw MTH, Hishikawa Y.: Ontogenetic changes in the expression of estrogen receptor\u00a0\u03b2 in mouse duodenal epithelium. Clin Res Hepatol Gastroenterol. 39, 499-507, 2015<\/p>\n

2014<\/strong><\/strong>
\n<\/span><\/span><\/h2>\n

\u3010<\/strong>\u539f\u8457\u3011<\/strong><\/p>\n

Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, Koji T, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N.: Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells. J Cell Sci. 127:2040\u20132052, 2014<\/p>\n

Nakajima K, Shibata Y, Hishikawa Y<\/span><\/strong>, Suematsu T, Mori M, Fukuhara S, Koji T, Sawase T, Ikeda T.: Coexpression of Ang1 and Tie2 in Odontoblasts of Mouse Developing and Mature Teeth-A New Insight into Dentinogenesis. Acta Histochem. Cytochem. 47: 19\u201325, 2014<\/p>\n

2013 <\/strong><\/strong><\/span><\/h2>\n

\u3010\u8457\u66f8\u3011<\/strong>
\n\u83f1\u5ddd\u5584\u9686\uff1aIn situ<\/em> hybridization \u6cd5\u306e\u539f\u7406\u3068\u57fa\u790e\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b66<\/strong><\/em>\uff1a2013. 63-76, 2013.\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\uff08\u7de8\uff09\uff0c\u4e2d\u897f\u5370\u5237\uff0e<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff1a\u5f62\u614b\u79d1\u5b66\u3092\u57fa\u76e4\u3068\u3057\u305f\u907a\u4f1d\u5b50\u30fb\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u767a\u73fe\u30fb\u6a5f\u80fd\u89e3\u6790\u6cd5\u306e\u5b9f\u969b\uff0e\u5bae\u5d0e\u533b\u4f1a\u8a8c<\/strong><\/em> 37:79-87, 2013<\/p>\n

2012 <\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

An S, Soe K, Akamatsu M, Hishikawa Y, Koji T.: Accelerated proliferation of hepatocytes in rats with iron overload after partial hepatectomy. Histochem Cell Biol.<\/em><\/strong>138: 773-786, 2012.<\/p>\n

Choijookhuu N, Sato Y, Nishino T, Endo D, Hishikawa Y, Koji T.: Estrogen-dependent regulation of sodium\/hydrogen exchanger-3 (NHE3) expression via estrogen receptor \u03b2 in proximal colon of pregnant mice. Histochem Cell Biol.<\/em><\/strong>137:575-587,2012.<\/p>\n

Kitamura M, Nishino T, Obata Y, Furusu A, Hishikawa Y, Koji T, Kohno S.: Epigallocatechin gallate suppresses peritoneal fibrosis in mice. Chemico-Biological Interactions<\/em><\/strong> 195: 95-104, 2012.<\/p>\n

2011 <\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Song N, Liu J, An S, Nishino T, Hishikawa Y, Koji T.: Immunohistochemical analysis of histone H3 modifications in germ cells during mouse spermatogenesis. Acta Histochem. Cytochem<\/em><\/strong>. 44:183-190, 2011.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff1a\uff11\u7ae0 \u5f62\u614b\u5b66\u7684\u691c\u51fa\u6cd5\uff0e\uff12\u7bc0 \u5149\u5b66\u9855\u5fae\u93e1\uff0d\u514d\u75ab\u7d44\u7e54\u5316\u5b66\uff0e\u5b9f\u9a13\u533b\u5b66\u5225\u518a \u7d30\u80de\u6b7b\u5b9f\u9a13\u30d7\u30ed\u30c8\u30b3\u30fc\u30eb<\/strong><\/em>\uff1a30-41, 2011\uff0e\u5200\u7962\u91cd\u4fe1\uff0c\u5c0f\u8def\u6b66\u5f66\uff08\u7de8\uff09\uff0c\u7f8a\u571f\u793e\uff0e<\/p>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a17\uff0eIn situ<\/em> hybridization\uff0e\u75c5\u6c17\u306e\u5206\u5b50\u5f62\u614b\u5b66<\/strong><\/em>\uff1a66-69, 2011\uff0e\u65e5\u672c\u81e8\u5e8a\u5206\u5b50\u5f62\u614b\u5b66\u4f1a\uff08\u7de8\uff09\uff0c\u5b66\u969b\u4f01\u753b\uff0e<\/p>\n

2010 <\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Yamamoto-Fukuda T, Hishikawa Y, Shibata Y, Kobayashi T, Takahashi H, Koji T.: Pathogenesis of middle ear cholesteatoma; a new model of experimentally induced cholesteatoma in mongolian gerbils. Am. J. Pathol.<\/em><\/strong> 176:2602-2606, 2010.<\/p>\n

Abo T, Nagayasu T, Hishikawa Y, Tagawa T, Nanashima A, Yamayoshi T, Matsumoto K, An S, Koji T.: Expression of keratinocyte growth factor and its receptor in rat tracheal cartilage: Possible involvement in wound healing of the damaged cartilage. Acta Histochem. Cytochem.<\/strong><\/em> 43:89-98, 2010.<\/p>\n

Kakugawa T, Mukae H, Hishikawa Y, Ishii H, Sakamoto N, Ishimatsu Y, Fujii T, Koji T, Kohno S.: Localization of HSP47 mRNA in murine bleomycin-induced pulmonary fibrosis. Virchows Archiv.<\/strong><\/em> 456:309-315, 2010.<\/p>\n

Yamamoto-Fukuda T, Takahashi H, Terakado M, Hishikawa Y, Koji T.: Expression of keratinocyte growth factor and its receptor in noncholesteatomatous and cholesteatomatous chronic otitis media. Otol. Neurotol.<\/strong><\/em> 31:745-751, 2010.<\/p>\n

Tokunaga T, Naruke Y, Shigematsu S, Kohno T, Yasui K, Ma Y, Chua KJ, Katayama I, Nakamura T, Hishikawa Y, Koji T, Yatabe Y, Nagayasu T, Fujita T, Matsuyama T, Hayashi H.: Aberrant expression of interferon regulatory factor 3 in human lung cancer. Biochem. Biophys. Res. Commun.<\/strong><\/em> 397:202-207, 2010.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1aB. In situ<\/em> \u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3 In situ\u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\u306e\u57fa\u790e\u3068\u5fdc\u7528\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b662010<\/strong><\/em>\uff1a47-60, 2010\uff0e\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\uff08\u7de8\uff09\uff0c\u5b66\u969b\u4f01\u753b.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

\u5c0f\u8def\u6b66\u5f66\uff0c\u83f1\u5ddd\u5584\u9686\uff1a\u75c5\u7406\u5b66\u7684\u907a\u4f1d\u5b50\u89e3\u6790\uff08in situ<\/em> hybridization, in situ<\/em> PCR, \u304a\u3088\u3073HELMET\uff09\uff0e\u65e5\u672c\u81e8\u5e8a<\/strong><\/em> 68\uff08\u5897\u520a\u53f78\uff09:219-226, 2010.<\/p>\n

2009<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Matsumoto K, Nagayasu T, Hishikawa Y, Tagawa T, Yamayoshi T, Abo T, Tobinaga S, Furukawa K, Koji T.: Keratinocyte growth factor accelerates compensatory growth in the remaining lung after trilobectomy in rats. J. Thorac. Cardiovasc. Surg.<\/strong><\/em> 137:1499-1507, 2009.<\/p>\n

Shirendeb U, Hishikawa Y, Moriyama S, Win N, Thu MMM, Mar KS, Khatanbaatar G, Masuzaki H, Koji T.: Human papillomavirus infection and its possible correlation with p63 expression in cervical cancer in Japan, Mongolia, and Myanmar. Acta Histochem. Cytochem.<\/strong><\/em> 42:181-190, 2009.<\/p>\n

Hishikawa Y, An S, Yamamoto-Fukuda T, Shibata Y, Koji T.: Improvement of in situ<\/em> PCR by optimization of PCR cycle number and proteinase K concentration: Localization of X chromosome-linked phosphoglycerate kinase-1 gene in mouse reproductive organs. Acta Histochem. Cytochem.<\/strong><\/em> 42:15-21, 2009.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff1a\u7b2c8\u7ae0 \u7cbe\u5de3\u306e\u75c5\u7406\u5b66\uff0e\u6c38\u9060\u306e\u4e0d\u6b7b\uff0d\u7cbe\u5b50\u5f62\u6210\u7d30\u80de\u306e\u751f\u7269\u5b66<\/strong><\/em>\uff1a97-116, 2009\uff0e\u5c0f\u8def\u6b66\u5f66\uff08\u7de8\uff09\uff0c\u30b5\u30a4\u30a8\u30f3\u30b9\u793e.<\/p>\n

2008<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Yamamoto-Fukuda T, Terakado M, Hishikawa Y, Koji T, Takahashi H.: Topical application of 5-fluorouracil on attic cholesteatoma results in downregulation of keratinocyte growth factor and reduction of proliferative activity. Eur. Arch. Otorhinolaryngol.<\/strong><\/em> 265:1173-1178, 2008.<\/p>\n

Koji T, Kondo S, Hishikawa Y, An S, Sato Y.: In situ<\/em> detection of methylated DNA by histo endonuclease-linked detection of methylated DNA sites: a new principle of analysis of DNA methylation. Histochem. Cell Biol.<\/strong><\/em> 130:917-925, 2008.<\/p>\n

Nagai K, Jinnai I, Hata T, Usui T, Sasaki D, Tsukasaki K, Sugahara K, Hishikawa Y, Yamada Y, Tanaka Y, Koji T, Mano H, Kamihira S, Tomonaga M.: Adhesion-dependent growth of primary adult T cell leukemia cells with down-regulation of HTLV-1 p40Tax protein: a novel in vitro model of the growth of acute ATL cells. Int. J. Hematol.<\/strong><\/em> 88:551-564, 2008.<\/p>\n

Nakagawa T, Kajitani T, Togo S, Masuko N, Ohdan H, Hishikawa Y, Koji T, Matsuyama T, Ikura T, Muramatsu M, Ito T.: Deubiquitylation of histone H2A activates transcriptional initiation via trans<\/em>-histone cross-talk with H3K4 di- and trimethylation. Gene Dev.<\/strong><\/em> 22:37-49, 2008.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1aB. In situ<\/em> \u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\u6cd5\uff0eIn situ\u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\u306e\u57fa\u790e\u3068\u5fdc\u7528\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b662008<\/strong><\/em>\uff1a35-49, 2008\uff0e\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\uff08\u7de8\uff09\uff0c\u5b66\u969b\u4f01\u753b.<\/p>\n

2007<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Jimbo R, Sawase T, Shibata Y, Hirata K, Hishikawa Y, Tanaka Y, Bessho K, Ikeda T, Atsuta M.: Enhanced osseointegration by the chemotactic activity of plasma fibronectin for cellular fibronectin positive cells. Biomaterials<\/strong><\/em> 28:3469-3477, 2007.<\/p>\n

An S, Hishikawa Y, Liu J, Koji T.: Lung injury after ischemia-reperfusion of small intestine in rats involves apoptosis of type II alveolar epithelial cells mediated by TNF-\u03b1 and activation of Bid pathway. Apoptosis<\/strong><\/em> 12:1989-2001, 2007.<\/p>\n

Mochizuki K, Ohno Y, Kanematsu T, Sakurai-Yamashita Y, Niwa M, Hishikawa Y, Koji T.: Possible protection of sinusoidal endothelial cells by endothelin B receptor during hepatic warm ischemia-reperfusion. Surg. Today<\/strong><\/em> 37:460-467, 2007.<\/p>\n

Matsuo Y, Nomata K, Eguchi J, Aoki D, Hayashi T, Hishikawa Y, Kanetake H, Shibata Y, Koji T.: Immunohistochemical analysis of connexin43 expression in infertile human testes. Acta Histochem. Cytochem.<\/strong><\/em> 40:69-75, 2007.<\/p>\n

Soe K, Hishikawa Y, Fukuzawa Y, Win N, Yin KS, Win KM, Myint AA, Koji T.: Possible correlation between iron deposition and enhanced proliferating activity in hepatitis C virus-positive hepatocellular carcinoma in Myanmar (Burma). J. Gastroenterol.<\/strong><\/em> 42:225-235, 2007.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u5c0f\u8def\u6b66\u5f66\uff0c\u6c5f\u5cf6\u90a6\u660e\uff0c\u83f1\u5ddd\u5584\u9686\uff1a\u7b2c12\u7ae0 \u30d2\u30c8\u306e\u767a\u751f\u30fb\u907a\u4f1d\u30fb\u8001\u5316\uff0e\u30d3\u30b8\u30e5\u30a2\u30eb\u89e3\u5256\u751f\u7406\u5b66<\/strong><\/em>\uff1a365-384, 2007\uff0e\u85e4\u672c \u6df3\uff08\u76e3\u4fee\uff09\uff0c\u30cc\u30fc\u30f4\u30a7\u30eb\u30d2\u30ed\u30ab\u30ef.<\/p>\n

2006<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Ulziibat S, Ejima K, Shibata Y, Hishikawa Y, Kitajima M, Fujishita A, Ishimaru T, Koji T.: Identification of estrogen receptor \u03b2-positive intraepithelial lymphocytes and their possible roles in normal and tubal pregnancy oviducts. Hum. Reprod.<\/strong><\/em> 21:2281-2289, 2006.<\/p>\n

Mapendano CK, Kishino T, Miyazaki K, Kondo S, Yoshiura K, Hishikawa Y, Koji T, Niikawa N, Ohta T.: Expression of the Snurf-Snrpn IC transcript in the oocyte and its putative role in the imprinting establishment of the mouse 7C imprinting domain. J. Hum. Genet.<\/strong><\/em> 51:236-243, 2006.<\/p>\n

Shukuwa K, Izumi S, Hishikawa Y, Ejima K, Inoue S, Muramatsu M, Ouchi Y, Kitaoka T, Koji T.: Diethylstilbestrol increases the density of prolactin cells in male mouse pituitary by inducing proliferation of prolactin cells and transdifferentiation of gonadotropic cells. Histochem. Cell Biol.<\/strong><\/em> 126:111-123, 2006.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u67f4\u7530\u606d\u660e\uff0c\u83f1\u5ddd\u5584\u9686\uff0c\u6c60\u7530 \u901a\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a\u7b2c5\u7ae0 mRNA\u691c\u51fa\u306e\u305f\u3081\u306ein situ\u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\uff0e\u67d3\u8272\u30fb\u30d0\u30a4\u30aa\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b9f\u9a13\u30cf\u30f3\u30c9\u30d6\u30c3\u30af<\/strong><\/em>\uff1a111-120, 2006\uff0e\u9ad8\u7530\u90a6\u662d\uff0c\u9f4b\u85e4\u5c1a\u4eae\uff0c\u5ddd\u4e0a\u901f\u4eba\uff08\u7de8\uff09\uff0c\u7f8a\u571f\u793e.<\/p>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a\u7b2c6\u7ae0 \u30b5\u30a6\u30b9\u30a6\u30a7\u30b9\u30bf\u30f3\u7d44\u7e54\u5316\u5b66\uff0e\u67d3\u8272\u30fb\u30d0\u30a4\u30aa\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b9f\u9a13\u30cf\u30f3\u30c9\u30d6\u30c3\u30af<\/strong><\/em>\uff1a189-194, 2006\uff0e\u9ad8\u7530\u90a6\u662d\uff0c\u9f4b\u85e4\u5c1a\u4eae\uff0c\u5ddd\u4e0a\u901f\u4eba\uff08\u7de8\uff09\uff0c\u7f8a\u571f\u793e.<\/p>\n

2005 <\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Iwanaga H, Matsumoto T, Enomoto H, Okano K, Hishikawa Y, Shindo H, Koji T.: Enhanced expression of insulin-like growth factor-binding proteins in human osteoarthritic cartilage detected by immunohistochemistry and in situ<\/em> hybridization. Osteoarthr. Cartilage<\/strong><\/em> 13:439-448, 2005.<\/p>\n

An S, Hishikawa Y, Koji T.: Induction of cell death in rat small intestine by ischemia reperfusion: differential roles of Fas\/Fas ligand and Bcl-2\/Bax systems depending upon cell types. Histochem. Cell Biol.<\/strong><\/em> 123:249-261, 2005.<\/p>\n

Shirota K, Tateishi K, Koji T, Hishikawa Y, Hachisuga T, Kuroki M, Kawarabayashi T.: Early human preantral follicles have relaxin and relaxin receptor (LGR7), and relaxin promotes their development. J. Clin. Endocrinol. Metab.<\/strong><\/em> 90:516-521, 2005.<\/p>\n

Hira E, Ono T, Dhar DK, El-Assal ON, Hishikawa Y, Yamanoi A, Nagasue N.: Overexpression of macrophage migration inhibitory factor induces angiogenesis and deteriorates prognosis after radical resection for hepatocellular carcinoma. Cancer<\/strong><\/em> 103:588-598, 2005.<\/p>\n

Fukushima C, Matsuse H, Hishikawa Y, Kondo Y, Machida I, Saeki S, Kawano T, Tomari S, Obase Y, Shimoda T, Koji T, Kohno S.: Pranlukast, a leukotriene receptor antagonist, inhibits interleukin-5 production via a mechanism distinct from leukotriene receptor antagonism. Int. Arch. Allergy Immunol.<\/strong><\/em> 136:165-172, 2005.<\/p>\n

Sun F, Kawasaki E, Akazawa S, Hishikawa Y, Sugahara K, Kamihira S, Koji T, Eguchi K.: Apoptosis and its pathway in early post-implantation embryos of diabetic rats. Diabetes Res. Clin. Pract.<\/strong><\/em> 67:110-118, 2005.<\/p>\n

2004 <\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Aoki D, Yamamoto-Fukuda T, Hishikawa Y, Nakamura M, Sakai H, Kanetake H, Koji T.: Coexpression of keratinocyte growth factor and its receptor in normal and prostate cancer tissues: possible formation of autonomous andromedin loop. Acta Histochem. Cytochem.<\/strong><\/em> 37:379-389, 2004.<\/p>\n

Hishikawa Y, Tamaru N, Ejima K, Hayashi T, Koji T.: Expression of keratinocyte growth factor and its receptor in human breast cancer: its inhibitory role in the induction of apoptosis possibly through the overexpression of Bcl-2. Arch. Histol. Cytol.<\/strong><\/em> 67:455-464, 2004.<\/p>\n

Tamaru N, Hishikawa Y, Ejima K, Nagasue N, Inoue S, Muramatsu M, Hayashi T, Koji T.: Estrogen receptor-associated expression of keratinocyte growth factor and its possible role in the inhibition of apoptosis in human breast cancer. Lab. Invest.<\/strong><\/em> 84:1460-1471, 2004.<\/p>\n

Kawano N, Koji T, Hishikawa Y, Murase K, Murata I, Kohno S.: Identification and localization of estrogen receptor \u03b1- and \u03b2-positive cells in adult male and female mouse intestine at various estrogen levels. Histochem. Cell Biol.<\/strong><\/em> 121:399-405, 2004.<\/p>\n

Yamayoshi T, Nagayasu T, Matsumoto K, Abo T, Hishikawa Y, Koji T.: Expression of keratinocyte growth factor\/fibroblast growth factor-7 and its receptor in human lung cancer: correlation with tumour proliferative activity and patient prognosis. J. Pathol.<\/strong><\/em> 204:110-118, 2004.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1aIV\uff0eSouthwestern Histochemistry\u306e\u7406\u8ad6\u3068\u5b9f\u969b\u7684\u5fdc\u7528\uff0e\u7d44\u7e54\u7d30\u80de\u5316\u5b662004<\/strong><\/em>\uff1a111-118, 2004\uff0e\u65e5\u672c\u7d44\u7e54\u7d30\u80de\u5316\u5b66\u4f1a\uff08\u7de8\uff09\uff0c\u5b66\u969b\u4f01\u753b.<\/p>\n

2003<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Tsurusaki T, Aoki D, Kanetake H, Inoue S, Muramatsu M, Hishikawa Y, Koji T.: Zone-dependent expression of estrogen receptors \u03b1 and \u03b2 in human benign prostatic hyperplasia. J. Clin. Endocrinol. Metab.<\/strong><\/em> 88:1333-1340, 2003.<\/p>\n

Ueda S, Yamanoi A, Hishikawa Y, Dhar DK, Tachibana M, Nagasue N.: Transforming growth factor-\u03b2 1 released from the spleen exerts a growth inhibitory effect on liver regeneration in rats. Lab. Invest.<\/strong><\/em> 83:1595-1603, 2003.<\/p>\n

Nonaka MI, Hishikawa Y, Moriyama N, Koji T, Ogata RT, Kudo A, Kawakami H, Nonaka M.: Complement C4b-binding protein as a novel murine epididymal secretory protein. Biol. Reprod.<\/strong><\/em> 69:1931-1939, 2003.<\/p>\n

Okada K, Nakashima M, Komuta K, Hashimoto S, Okudaira S, Baba N, Hishikawa Y, Koji T, Kanematsu T, Watanabe T.: Expression of tumor-associated membrane antigen, RCAS1, in human colorectal carcinomas and possible role in apoptosis of tumor-infiltrating lymphocytes. Mod. Path.<\/strong><\/em> 16: 679-685, 2003.<\/p>\n

Imaizumi Y, Murota H, Kanda S, Hishikawa Y, Koji T, Taguchi T, Tanaka Y, Yamada Y, Ikeda S, Kohno T, Yamamoto K, Mori N, Tomonaga M, Matsuyama T.: Expression of the c-Met proto-oncogene and its possible involvement in liver invasion in adult T-cell leukemia. Clin. Cancer Res.<\/strong><\/em> 9:181-187, 2003.<\/p>\n

Yamamoto-Fukuda T, Aoki D, Hishikawa Y, Kobayashi T, Takahashi H, Koji T.: Possible involvement of keratinocyte growth factor and its receptor in enhanced epithelial-cell proliferation and acquired recurrence of middle-ear cholesteatoma. Lab. Invest.<\/strong><\/em> 83:123-136, 2003.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

Koji T, Izumi S, Hishikawa Y.: Molecular histochemistry of rRNAs by nonradioactive in situ<\/em> hibyridization at light- and electron-microscopic levels. In: Advancement of Life Science<\/strong><\/em>:141-146, 2003. Setsu, Roan(eds). Amvo Publishing Company.<\/p>\n

Hishikawa Y, Izumi S, Koji T.: Southwestern histochemical analysis of estrogen responsive element in paraffin-embedded tissue sections of mouse ovary. In: Advancement of Life Science<\/strong><\/em>:147-152, 2003. Setsu, Roan(eds). Amvo Publishing Company.<\/p>\n

Izumi S, Takano K, Hishikawa Y, Koji T.: In situ<\/em> hybridization of prolactin mRNA in rat pituitary sections: Backscattered electron mode analysis using light microscopic specimen on glass slides. In: Advancement of Life Science<\/strong><\/em>:153-158, 2003. Setsu, Roan(eds). Amvo Publishing Company.<\/p>\n

An S, Hishikawa Y, Koji T.: Induction of apoptosis in the crypts of rat small intestine by ischemia-reperfusion. In: Advancement of Life Science<\/strong><\/em>:159-164, 2003. Setsu, Roan(eds). Amvo Publishing Company.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1aIn situ<\/em> hybridization\u306b\u3088\u308b\u30b2\u30ce\u30e0\u8ee2\u5199\u7269\u306e\u5c40\u5728\u8a3c\u660e\u3068\u5b9a\u91cf\u7684\u89e3\u6790\uff0e\u7d30\u80de<\/strong><\/em> 35\uff1a489-493, 2003.<\/p>\n

Koji T, Hishikawa Y.: Germ cell apoptosis and its molecular trigger in mouse testes. Arch. Histol. Cytol.<\/strong><\/em> 66:1-16, 2003.<\/p>\n

Hishikawa Y, Damavandi E, Izumi S, Koji T.: Molecular histochemical analysis of estrogen receptor \u03b1 and \u03b2 expressions in the mouse ovary: In situ<\/em> hybridization and Southwestern histochemistry. Med. Electron Microsc.<\/em><\/strong> 36:67-73, 2003.<\/p>\n

2002<\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Damavandi E, Hishikawa Y, Izumi S, Shin M, Koji T.: Involvement of Bax redistribution in the induction of germ cell apoptosis in neonatal mouse testes. Acta Histochem. Cytochem.<\/strong><\/em> 35:449-459, 2002.<\/p>\n

Kondo T, Goto S, Ihara Y, Urata Y, Ikeda S, Hishikawa Y, Izumi S, Shin M, Koji T.: Diethylstilbestrol attenuates antioxidant activities in testis from male mice. Free Radic. Res.<\/strong><\/em> 36:957-966, 2002.<\/p>\n

Shibata Y, Hishikawa Y, Izumi S, Fujita S, Yamaguchi A, Koji T.: Involvement of Fas\/Fas ligand in the induction of apoptosis in chronic sialadenitis of minor salivary glands including Sj\u00f6gren’s Syndrome. Hum. Cell<\/strong><\/em> 15:52-60, 2002.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

Shin M, Hishikawa Y, Izumi S, Koji T.: Southwestern histochemistry as a molecular histochemical tool for analysis of expression of transcription factors: Application to paraffin embedded tissue sections. Med. Electron Microsc.<\/strong><\/em> 35:217-224, 2002.<\/p>\n

\u672b\u677e\u8cb4\u53f2\uff0c\u548c\u6cc9\u4f38\u4e00\uff0c\u9032 \u6b63\u5fd7\uff0c\u83f1\u5ddd\u5584\u9686\uff0c\u7530\u53e3 \u5c1a\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a\u96fb\u9855ISH\u306b\u3088\u308b\u6838\u5185RNA\u306e\u5c40\u5728\u691c\u8a0e\uff0e\u96fb\u5b50\u9855\u5fae\u93e1<\/strong><\/em> 37:92-95, 2002.<\/p>\n

\u548c\u6cc9\u4f38\u4e00\uff0c\u83f1\u5ddd\u5584\u9686\uff0c\u9032 \u6b63\u5fd7\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u5f62\u614b\u5b66\u7684\u7279\u5fb4\uff0e\u6700\u65b0\u533b\u5b66<\/strong><\/em> 57:2454-2459, 2002.<\/p>\n

2001<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Koji T, Hishikawa Y, Ando H, Nakanishi Y, Kobayashi N.: Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis. Biol. Reprod.<\/strong><\/em> 64:946-954, 2001.<\/p>\n

Hishikawa Y, Kohno H, Ueda S, Kimoto T, Dhar DK, Kubota H, Tachibana M, Koji T, Nagasue N.: Expression of metallothionein in colorectal cancers and synchronous liver metastases. Oncology<\/strong><\/em> 61:162-167, 2001.<\/p>\n

Sawada T, Koji T, Hishikawa Y, Kishimoto K, Nagayasu T, Takahashi T, Oka T, Ayabe H.: Partial tolerance of subcutaneously transplanted xenogeneic tumour cell graft by Fas-mediated immunosuppression. Immunology<\/strong><\/em> 103:81-89, 2001.<\/p>\n

Izumi S, Shin M, Hishikawa Y, Koji T.: Immunoelectron microscopic identification of tRNA on ribosome particles in rat liver and placenta. J. Electr. Microsc. Technol. Med. Biol.<\/strong><\/em> 15:72-75, 2001.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1ain situ<\/em> PCR\u6cd5\uff0e\u7d30\u80de<\/strong><\/em> 33:196-199, 2001.<\/p>\n

Izumi S, Shin M, Hishikawa Y, Koji T.: Localization in situ<\/em> of specific RNA by light and electron microscopy. Ital. J. Anat. Embryol.<\/strong><\/em> 106:45-50, 2001.<\/p>\n

2000<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Yamamoto-Fukuda T, Shibata Y, Hishikawa Y, Shin M, Yamaguchi A, Kobayashi T, Koji T.: Effects of various decalcification protocols on detection of DNA strand breaks by terminal dUTP nick end labelling. Histochem. J.<\/strong><\/em> 32:697-702, 2000.<\/p>\n

Sutoh I, Kohno H, Nakashima Y, Hishikawa Y, Tabara H, Tachibana M, Kubota H, Nagasue N.: Concurrent expressions of metallothionein, glutathione-S-transferase-\u03c0 and P-glycoprotein in colorectal cancers. Dis. Colon Rectum<\/strong><\/em> 43:221-232, 2000.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a In situ<\/em> hybridization 3. mRNA in situ<\/em> hybridization\u306e\u57fa\u672c\u7684\u6280\u6cd5 2)\u653e\u5c04\u6027\u30d7\u30ed\u30fc\u30d6\u3068\u975e\u653e\u5c04\u6027\u30d7\u30ed\u30fc\u30d6\u306e\u6bd4\u8f03\uff0e\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u3068in situ <\/strong><\/em>hybridization<\/strong>\u306e\u3059\u3079\u3066 \u75c5\u7406\u3068\u81e8\u5e8aVol. 18. \u81e8\u6642\u5897\u520a\u53f7<\/strong><\/em>\uff1a252-257, 2000. \u9577\u6751\u7fa9\u4e4b\uff0c\u7b39\u91ce\u516c\u4f38\uff08\u7de8\uff09\uff0c\u6587\u5149\u5802.<\/p>\n

Hishikawa Y, Murakami M, Kasahara M, Nagasue N.:Chapter 11 In situ<\/em> hybridization for RNA: Nonradioactive probe: Oligo-DNA probe: T-T dimer. In: Molecular Histochemical Techniques<\/strong><\/em>:153-171, 2000. Koji(ed), Springer.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

\u548c\u6cc9\u4f38\u4e00\uff0c\u9032 \u6b63\u5fd7\uff0c\u83f1\u5ddd\u5584\u9686\uff0c\u5c0f\u8def\u6b66\u5f66\uff1a\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u304a\u3088\u3073\u30b5\u30a6\u30b9\u30a6\u30a7\u30b9\u30bf\u30f3\u7d44\u7e54\u5316\u5b66\u306e\u96fb\u9855\u6280\u8853\uff0e\u533b\u5b66\u751f\u7269\u5b66\u96fb\u5b50\u9855\u5fae\u93e1\u6280\u8853\u5b66\u4f1a\u8a8c<\/strong><\/em> 15:64-69, 2000.<\/p>\n

1999<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Tachibana M, Tabara H, Kotoh T, Kinugasa S, Dhar DK, Hishikawa Y, Masunaga R, Kubota H, Nagasue N.: Prognostic significance of perioperative blood transfusions in resectable thoracic esophageal cancer. Am. J. Gastroenterol.<\/strong><\/em> 94:757-765, 1999.<\/p>\n

Hishikawa Y, Koji T, Dhar DK, Kinugasa S, Yamaguchi M, Nagasue N.: Metallothionein expression correlates with metastatic and proliferative potential in squamous cell carcinoma of the oesophagus. Br. J. Cancer<\/strong><\/em> 81:712-720, 1999.<\/p>\n

Monden N, Abe S, Hishikawa Y, Yoshimura H, Kinugasa S, Dhar DK, Tachibana M, Nagasue N.: The role of P-glycoprotein in human gastric cancer xenografts in response to chemotherapy. Int. J. Surg. Investig.<\/strong><\/em> 1:3-10, 1999.<\/p>\n

1998<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Kinugasa S, Abe S, Tachibana M, Hishikawa Y, Yoshimura H, Monden N, Dhar DK, Nagasue N.: Overexpression of transforming growth factor-\u03b21 in scirrhous carcinoma of the stomach correlates with decreased survival. Oncology<\/strong><\/em> 55:582-587, 1998.<\/p>\n

\u3010\u8457\u66f8\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686\uff1a\u7b2c\u4e8c\u7ae0 IV. \u30d1\u30e9\u30d5\u30a3\u30f3\u5207\u7247\u306ein situ<\/em> hybridization\uff0eIn situ <\/strong><\/em>hybridization<\/strong>\u6280\u6cd5<\/strong><\/em>\uff1a164-171, 1998\uff0e\u5c0f\u8def\u6b66\u5f66\uff08\u7de8\uff09\uff0c\u5b66\u969b\u4f01\u753b.<\/p>\n

1997<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Monden N, Abe S, Sutoh I, Hishikawa Y, Kinugasa S, Nagasue N.: Prognostic significance of the expressions of metallothionein, glutathione-S-transferase-\u03c0, and P-glycoprotein in curatively resected gastric cancer. Oncology<\/strong><\/em> 54:391-399, 1997.<\/p>\n

Hishikawa Y, Abe S, Kinugasa S, Yoshimura H, Monden N, Igarashi M, Tachibana M, Nagasue N.: Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer. Oncology<\/strong><\/em> 54: 342-347, 1997.<\/p>\n

Yamaguchi M, Yu L, Hishikawa Y, Yamanoi A, Kubota H, Nagasue N.: Growth kinetic study of human hepatocellular carcinoma using proliferating cell nuclear antigen and Lewis Y antigen: their correlation with transforming growth factor-\u03b1 and \u03b2 1. Oncology<\/strong><\/em> 54:245-251, 1997.<\/p>\n

1996<\/strong><\/strong><\/span><\/h2>\n

\u3010\u539f\u8457\u3011<\/h3>\n

Kinugasa S, Tachibana M, Hishikawa Y, Abe S, Yoshimura H, Monden N, Dhar DK, Nagasue N.: Prognostic significance of proliferating cell nuclear antigen (PCNA) in squamous cell carcinoma of the esophagus. Jpn. J. Clin. Oncol.<\/strong><\/em> 26:405-410, 1996.<\/p>\n

1993<\/strong><\/strong><\/span><\/h2>\n

\u3010\u75c7\u4f8b\u5831\u544a\u3011<\/h3>\n

\u83f1\u5ddd\u5584\u9686, \u4e94\u5341\u5d50\u96c5\u5f66, \u677e\u5c3e \u9032, \u4e2d\u6751\u8f1d\u4e45: \u98df\u9053\u30a2\u30ab\u30e9\u30b7\u30a2\u306b\u5408\u4f75\u3057\u305f\u5f8c\u5929\u6027\u5168\u7d50\u8178hypoganglionosis\u306e\u4e00\u4f8b -\u9175\u7d20\u6297\u4f53\u6cd5\u306b\u3088\u308b\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u7684\u691c\u8a0e-. \u65e5\u672c\u5c0f\u5150\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c<\/strong><\/em> 29:1273-1276, 1993.<\/p>\n

\u3010\u7dcf\u8aac\u3011<\/h3>\n

\u4e45\u4fdd\u7530\u535a\u6587, \u4e94\u5341\u5d50\u96c5\u5f66, \u6df1\u6fa4\u516c\u6717, \u83f1\u5ddd\u5584\u9686, \u677e\u5c3e \u9032, \u672b\u6c38\u76f4\u6587, \u4e2d\u6751\u8f1d\u4e45\uff1a\u4e73\u764c\u306b\u5bfe\u3059\u308b\u4e73\u623f\u6e29\u5b58\u624b\u885328\u4f8b\u306e\u7d4c\u9a13\uff0e\u4e73\u764c\u306e\u81e8\u5e8a<\/strong><\/em> 8:270-274, 1993.<\/p>\n","protected":false},"excerpt":{"rendered":"

2026 \u3010\u539f\u8457\u3011 Fidya, Ishizuka T, Kubota T, Kai K, Hishikawa Y.\u00a0The Crucial Role of GPR30 and Histone Crotonylation … <\/p>\n

\u7d9a\u304d\u3092\u8aad\u3080 »<\/a><\/p>\n","protected":false},"author":31,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false},"_links":{"self":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/pages\/50"}],"collection":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/users\/31"}],"replies":[{"embeddable":true,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/comments?post=50"}],"version-history":[{"count":170,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/pages\/50\/revisions"}],"predecessor-version":[{"id":2391,"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/pages\/50\/revisions\/2391"}],"wp:attachment":[{"href":"http:\/\/www.med.miyazaki-u.ac.jp\/home\/anatomy1\/wp-json\/wp\/v2\/media?parent=50"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}